Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Marilyn L. Getchell"'
Autor:
Nico van Rooijen, Marilyn L. Getchell, Aaron S. Borders, Thomas V. Getchell, Donald A. Cohen, Jordan T. Etscheidt
Publikováno v:
The Journal of Comparative Neurology. 501:206-218
Apoptosis of olfactory sensory neurons (OSNs) induced by olfactory bulbectomy (OBX) leads to the activation of resident macrophages within the olfactory epithelium (OE). These macrophages phagocytose degenerating OSNs and secrete chemokines, which re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622893d191ea0304f9f33977f43b2498
https://doi.org/10.1002/cne.21252
https://doi.org/10.1002/cne.21252
Autor:
Marilyn L. Getchell, H. Fai Poon, Thomas V. Getchell, D. Allan Butterfield, Radhika A. Vaishnav
Publikováno v:
Neurobiology of Aging. 27:1010-1019
The brain is susceptible to oxidative stress, which is associated with age-related brain dysfunction, because of its high content of peroxidizable unsaturated fatty acids, high oxygen consumption per unit weight, high content of key components for ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2db2331b337e92b6db0a0d5afbbc63a
https://doi.org/10.1016/j.neurobiolaging.2005.05.006
https://doi.org/10.1016/j.neurobiolaging.2005.05.006
Autor:
Kevin Kwong, Arnold J. Stromberg, Thomas V. Getchell, Marilyn L. Getchell, Christopher P. Saunders
Publikováno v:
Physiology & Behavior. 87:848-856
We have investigated olfactory-mediated pre-ingestive behavior in leptin (ob/ob) and leptin receptor (db/db) mutant mice compared to age- and gender-matched wild-type (wt) mice. Olfactory-mediated behavior was tested using a buried food paradigm 5 ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d78e9ee86abadc832b24f4f55a4d03b
https://doi.org/10.1016/j.physbeh.2005.11.016
https://doi.org/10.1016/j.physbeh.2005.11.016
Autor:
Marilyn L. Getchell, D. Allan Butterfield, Radhika A. Vaishnav, H. Fai Poon, Thomas V. Getchell
Publikováno v:
Journal of Neurochemistry. 94:380-392
Decline in olfactory ability has been associated with aging as well as neurodegenerative disorders. The aim of this study was to gain fundamental insight into molecular events associated with the aging olfactory system. We report a comparative proteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::921f6f7145f7b1daa42e065242794f80
https://doi.org/10.1111/j.1471-4159.2005.03215.x
https://doi.org/10.1111/j.1471-4159.2005.03215.x
Autor:
Marilyn L. Getchell, Radhika A. Vaishnav, Kevin Kwong, Arnold J. Stromberg, Hua Liu, Thomas V. Getchell
Publikováno v:
Journal of Neuroscience Research. 80:309-329
Neurogenesis in the olfactory epithelium (OE) is induced by olfactory bulbectomy (OBX), which effectively axotomizes olfactory sensory neurons (OSNs) and removes their synaptic targets, resulting in apoptosis. We used Affymetrix high-density oligonuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391574d5de4b4cf599ff5e5b6f79b5b3
https://doi.org/10.1002/jnr.20411
https://doi.org/10.1002/jnr.20411
Publikováno v:
Neurobiology of Aging. 24:663-673
Olfactory sensory function is impaired in patients with the diagnosis of probable Alzheimer's disease (AD) compared to elderly controls, and the olfactory epithelium (OE) of AD patients exhibits several pathological changes characteristic of the AD b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0a6cc3a586b23c266deb60ded10c35
https://doi.org/10.1016/s0197-4580(02)00195-1
https://doi.org/10.1016/s0197-4580(02)00195-1
Publikováno v:
The Journal of Comparative Neurology. 435:60-77
Removal of the synaptic targets of olfactory receptor neurons by olfactory bulb ablation results in apoptosis of olfactory receptor neurons and up-regulation of proliferation of their progenitors. This study focuses on the expression of the neuropoie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b3bac1ffb755d72f3f9f693f1b8c2a
https://doi.org/10.1002/cne.1193
https://doi.org/10.1002/cne.1193
Publikováno v:
Cell and Tissue Research. 299:185-192
Transgenic mice in which overexpression of the transforming growth factor alpha (TGF-alpha) gene was directed by the keratin-14 promoter were used to study the regulation of cell cycle progression and proliferation in vivo in the olfactory epithelium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64452ffe2cf0670d9b09ecf78150c4f
https://doi.org/10.1007/s004410050016
https://doi.org/10.1007/s004410050016
Publikováno v:
The Journal of Comparative Neurology. 381:31-40
Superoxide dismutases (SODs) protect cells from damage by oxygen free radicals. Manganese (Mn) SOD is preferentially induced in terminally differentiating cells; induction of copper-zinc (CuZn) SOD is more closely associated with postnatal exposure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5d5f578f0868e2b24d1b6d07628e183
https://doi.org/10.1002/(sici)1096-9861(19970428)381:1<31::aid-cne3>3.0.co
https://doi.org/10.1002/(sici)1096-9861(19970428)381:1<31::aid-cne3>3.0.co
Publikováno v:
Brain Research. 707:303-307
The density of protein gene product 9.5- and tyrosine hydroxylase-immunoreactive nerve fibers innervating circumvallate papillae of the tongue was substantially increased in transgenic mice that overexpressed nerve growth factor (NGF) when compared w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c698874c7b87e2a642e9fe8805fa4fdf
https://doi.org/10.1016/0006-8993(95)01336-9
https://doi.org/10.1016/0006-8993(95)01336-9