Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Marilyn J. Woolkalis"'
Autor:
Kalyankar Mahadev, Satish P. RamachandraRao, Taishan Hu, Marilyn J. Woolkalis, Senthuran Siva, Yanqing Zhu, Barry J. Goldstein, Kumar Sharma, Cathryn Valancius, Irene Toh
Publikováno v:
American Journal of Physiology-Renal Physiology. 289:F816-F825
Cytoskeletal alterations in endothelial cells have been linked to nitric oxide generation and cell-cell interactions. Transforming growth factor (TGF)-beta has been described to affect cytoskeletal rearrangement in numerous cell types; however, the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df81e14cac6ac5b74ae6eea9289d57b
https://doi.org/10.1152/ajprenal.00024.2005
https://doi.org/10.1152/ajprenal.00024.2005
Publikováno v:
Journal of Biological Chemistry. 279:36142-36147
Tissue factor is critically important for initiating the activation of coagulation zymogens leading to the generation of thrombin. Quiescent endothelial cells do not express tissue factor on their surface, but many stimuli including cytokines and coa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1699ef055939abdf2aa1074b01e33607
https://doi.org/10.1074/jbc.m405039200
https://doi.org/10.1074/jbc.m405039200
Publikováno v:
Developmental Dynamics. 223:273-284
We show that alpha 6 integrin function was required for normal lens cell differentiation by using an antisense construct to suppress alpha 6 integrin expression. To elucidate the mechanism by which this integrin functions in the regulation of the len
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a9cd859125d31c28210158e80eff3f
https://doi.org/10.1002/dvdy.10050
https://doi.org/10.1002/dvdy.10050
Autor:
Donna S. Woulfe, Peter J. O'Brien, Nicolas Prevost, Marina Molino, Lawrence F. Brass, M.Katherine Hollinger, Marilyn J. Woolkalis
Publikováno v:
Journal of Biological Chemistry. 275:13502-13509
The recent identification of two new thrombin receptors, PAR3 and PAR4, led us to re-examine the basis for endothelial cell responses to thrombin. Human umbilical vein endothelial cells (HUVEC) are known to express PAR1 and the trypsin/tryptase recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddf72510dac7da86859c2995ed19061a
https://doi.org/10.1074/jbc.275.18.13502
https://doi.org/10.1074/jbc.275.18.13502
Autor:
Giulia Taraboletti, Lawrence F. Brass, Marina Molino, James A. Hoxie, Elliot S. Barnathan, Richard Horuk, Beth S. Haggarty, Nicolas Prevost, Joseph Hesselgesser, Marilyn J. Woolkalis, Domenico Praticò
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1500:227-240
It has been shown that deletion of the chemokine receptor, CXCR4, causes disordered angiogenesis in mouse models. In the present studies, we examined the distribution and trafficking of CXCR4 in human endothelial cells, tested their responses to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534e4fffc61bc3bc1bfdbc38782506cf
https://doi.org/10.1016/s0925-4439(99)00110-6
https://doi.org/10.1016/s0925-4439(99)00110-6
Autor:
Albana Cumashi, Robert Numerof, Marina Molino, Mark Dreyer, Norman Schechter, James A. Hoxie, James D. Clark, Elliot S. Barnathan, Marilyn J. Woolkalis, Lawrence F. Brass
Publikováno v:
Journal of Biological Chemistry. 272:4043-4049
Tryptase is a serine protease secreted by mast cells that is able to activate other cells. In the present studies we have tested whether these responses could be mediated by thrombin receptors or PAR-2, two G-protein-coupled receptors that are activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1635baf6da9556386cff5f4cc41f08
https://doi.org/10.1074/jbc.272.7.4043
https://doi.org/10.1074/jbc.272.7.4043
Publikováno v:
Shock. 4:361-367
Endotoxin stimulates synthesis of endothelin which can cause pulmonary and systemic vasoconstriction and bronchoconstriction. Prolonged endotoxemia in sheep results in dramatic increases in pulmonary and systemic vascular resistances in nonsurvivors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b4bf809481d6a9668d7f38cb87803a
https://doi.org/10.1097/00024382-199511000-00009
https://doi.org/10.1097/00024382-199511000-00009
Publikováno v:
Trends in Cardiovascular Medicine. 5:123-128
In the past several years, the identification of the human thrombin receptor has permitted considerable progress to be made in the understanding of the ways in which thrombin activates cells. To date, only a single receptor for thrombin has been iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd5bfd1c89194c55e472ec0bdaee27f4
https://doi.org/10.1016/1050-1738(95)00051-a
https://doi.org/10.1016/1050-1738(95)00051-a
Publikováno v:
Journal of Biological Chemistry. 270:9868-9875
Activated thrombin receptors on human umbilical vein endothelial cells rapidly undergo homologous desensitization, leaving the cells unable to respond to thrombin. The present studies examine the fate of activated thrombin receptors on endothelial ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382cac747da1d98f3399b8fba6242d3d
https://doi.org/10.1074/jbc.270.17.9868
https://doi.org/10.1074/jbc.270.17.9868