Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marilyn G. Pray-Grant"'
Autor:
Kristyna Kupkova, Savera J. Shetty, Marilyn G. Pray-Grant, Patrick A. Grant, Rashidul Haque, William A. Petri, David T. Auble
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-20 (2023)
Abstract Background Stunting is a global health problem affecting hundreds of millions of children worldwide and contributing to 45% of deaths in children under the age of five. Current therapeutic interventions have limited efficacy. Understanding t
Externí odkaz:
https://doaj.org/article/d2d3e2d7b9f44296856666ff5702d2fd
Publikováno v:
Mol Cell
Ants acquire distinct morphological and behavioral phenotypes arising from a common genome, underscoring the importance of epigenetic regulation. In Camponotus floridanus, “Major” workers defend the colony, but can be epigenetically reprogrammed
Autor:
Michael S, Torok, Marilyn G, Pray-Grant, Benjamin M, Grant, Meagan E, Josephs, Patrick A, Grant
Publikováno v:
J Mol Genet (Isleworth)
The post-translational acetylation of the histone components of chromatin mediates numerous DNA-templated events, including transcriptional activation, DNA repair, and genomic replication. The conserved SAGA (Spt-Ada-Gcn5 Acetyltranferase) and SLIK (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5e1ba9b7315898b4ff6de6bb8a2e2738
https://europepmc.org/articles/PMC7437354/
https://europepmc.org/articles/PMC7437354/
Publikováno v:
The FASEB Journal. 32
Publikováno v:
Proceedings of the National Academy of Sciences. 102:8478-8482
Histone acetyltransferases have been shown to participate in many essential cellular processes, particularly those associated with activation of transcription. SAGA (Spt-Ada-Gcn5 acetyltransferase) and SLIK (SAGA-like) are two highly homologous multi
Publikováno v:
Nature. 433:434-438
The specific post-translational modifications to histones influence many nuclear processes including gene regulation, DNA repair and replication. Recent studies have identified effector proteins that recognize patterns of histone modification and tra
Autor:
Patrick A. Grant, Jerry L. Workman, Amine Nourani, Marilyn G. Pray-Grant, LeAnn J. Howe, Jacques Côté
Publikováno v:
Journal of Biological Chemistry. 278:19171-19175
The inhibitor-of-growth (ING) family of proteins was founded by human ING1, a tumor suppressor interacting with p53 in vivo and required for its function in transcription/apoptosis. There are five different ING genes in humans, three of which have be
Autor:
Joseph C. Reese, John R. Yates, Marilyn G. Pray-Grant, David Schieltz, Patrick A. Grant, Jerry L. Workman, David J. Steger
Publikováno v:
Cell. 94:45-53
A number of transcriptional coactivator proteins have been identified as histone acetyltransferase (HAT) proteins, providing a direct molecular basis for the coupling of histone acetylation and transcriptional activation. The yeast Spt-Ada-Gcn5-acety
Publikováno v:
Molecular Pharmacology. 53:691-700
The role of protein kinase C (PKC) in the human aryl hydrocarbon receptor (hAhR) signal transduction pathway was examined in cell lines stably transfected with pGUDLUC6.1, in which luc+ is solely controlled by four dioxin-responsive elements (DREs).
Publikováno v:
Molecular and Cellular Biology. 18:978-988
Prior to ligand activation, the unactivated aryl hydrocarbon receptor (AhR) exists in a heterotetrameric 9S core complex consisting of the AhR ligand-binding subunit, a dimer of hsp90, and an unknown subunit. Here we report the purification of an app