Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Marilyn G. Farquhar"'
Autor:
Lingxia Qiao, Saptarshi Sinha, Amer Ali Abd El‐Hafeez, I‐Chung Lo, Krishna K Midde, Tony Ngo, Nicolas Aznar, Inmaculada Lopez‐Sanchez, Vijay Gupta, Marilyn G Farquhar, Padmini Rangamani, Pradipta Ghosh
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 4, Pp n/a-n/a (2023)
Abstract Cancers represent complex autonomous systems, displaying self‐sufficiency in growth signaling. Autonomous growth is fueled by a cancer cell's ability to “secrete‐and‐sense” growth factors (GFs): a poorly understood phenomenon. Usin
Externí odkaz:
https://doaj.org/article/fa7b3bde97544f3e97560e5c2c0d0fc4
Autor:
Nicolas Aznar, Arjun Patel, Cristina C Rohena, Ying Dunkel, Linda P Joosen, Vanessa Taupin, Irina Kufareva, Marilyn G Farquhar, Pradipta Ghosh
Publikováno v:
eLife, Vol 5 (2016)
Loss of epithelial polarity impacts organ development and function; it is also oncogenic. AMPK, a key sensor of metabolic stress stabilizes cell-cell junctions and maintains epithelial polarity; its activation by Metformin protects the epithelial bar
Externí odkaz:
https://doaj.org/article/242bdc21d8c94924921c7a66668db1a9
Autor:
Krishna Midde, I-Chung Lo, Pradipta Ghosh, Inmaculada Lopez-Sanchez, Saptarshi Sinha, Tony Ngo, Amer Ali Abd El-Hafeez, Vijay Gupta, Padmini Rangamani, Nicolas Aznar, Marilyn G. Farquhar, Lingxia Qiao
Cancers represent complex autonomous systems, displaying self-sufficiency in growth signaling. Autonomous growth is fueled by a cancer cell’s ability to ‘secrete-and-sense’ growth factors: a poorly understood phenomenon. Using an integrated sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f2cb155359294917a4e9bd25b2a6e2f
https://doi.org/10.1101/2021.03.18.436048
https://doi.org/10.1101/2021.03.18.436048
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49227 (2012)
Lysophosphatidic acid (LPA) mediates diverse cellular responses through the activation of at least six LPA receptors--LPA(1-6,) but the interacting proteins and signaling pathways that mediate the specificity of these receptors are largely unknown. W
Externí odkaz:
https://doaj.org/article/fe6bf662327a4288a7b4a1fe0a144925
Publikováno v:
The Journal of biological chemistry, vol 290, iss 11
Activation of trimeric G proteins has been traditionally viewed as the exclusive job of G protein-coupled receptors (GPCRs). This view has been challenged by the discovery of non-receptor activators of trimeric G proteins. Among them, GIV (a.k.a. Gir
Autor:
Cristina C. Rohena, Pradipta Ghosh, Linda P. Joosen, Marilyn G. Farquhar, Vanessa Taupin, Irina Kufareva, Ying Dunkel, Nicolas Aznar, Arjun Patel
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2016, 5, ⟨10.7554/eLife.20795⟩
eLife, Vol 5 (2016)
eLife, eLife Sciences Publication, 2016, 5, ⟨10.7554/eLife.20795⟩
eLife, Vol 5 (2016)
Loss of epithelial polarity impacts organ development and function; it is also oncogenic. AMPK, a key sensor of metabolic stress stabilizes cell-cell junctions and maintains epithelial polarity; its activation by Metformin protects the epithelial bar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75404412a39a46c0449bbb14304dc62c
https://hal.archives-ouvertes.fr/hal-03059632
https://hal.archives-ouvertes.fr/hal-03059632
Publikováno v:
The Journal of Cell Biology
ARH is required for the trafficking of megalin from early endosomes to the endocytic recycling compartment, where megalin undergoes intramembrane proteolysis, releasing a tail fragment that represses megalin transcription.
Receptors internalized
Receptors internalized
Autor:
Marilyn G. Farquhar
Publikováno v:
Annual Review of Cell and Developmental Biology. 28:1-28
In this perspective, I review the scientific career of George E. Palade, the man many consider to be the father of cell biology. Palade's scientific contributions spanned more than 50 years (from the late 1940s to 2001) and were amazingly diverse and
Autor:
Cristina C. Rohena, Pradipta Ghosh, Ying Dunkel, Vanessa Taupin, Nicolas Aznar, Arjun Patel, Marilyn G. Farquhar, Irina Kufareva, Linda P. Joosen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::462c6c14589704e1ca84ef6ef2313190
https://doi.org/10.7554/elife.20795.025
https://doi.org/10.7554/elife.20795.025
Autor:
I-Chung Lo, Nicolas Aznar, Pradipta Ghosh, Krishna Midde, Jason Ear, Vijay Gupta, Marilyn G. Farquhar, Inmaculada Lopez-Sanchez, Deepali Bhandari, Ingrid R. Niesman, Juan B. Blanco-Canosa, Mark von Zastrow, Mikel Garcia-Marcos, Anthony Leyme
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 39
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (39), pp.E5721-E5730. ⟨10.1073/pnas.1609502113⟩
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (39), pp.E5721-E5730. ⟨10.1073/pnas.1609502113⟩
We previously showed that guanine nucleotide-binding (G) protein α subunit (Gα)-interacting vesicle-associated protein (GIV), a guanine-nucleotide exchange factor (GEF), transactivates Gα activity-inhibiting polypeptide 1 (Gαi) proteins in respon