Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Marilyn G, Wiebe"'
Publikováno v:
AMB Express, Vol 12, Iss 1, Pp 1-9 (2022)
Key points Trichoderma D-221704 produced 53 g L−1 mucic acid in fed batch culture at pH 4.0 Yeast extract was beneficial, but not essential for good mucic acid production The ambr®250 gave good, reproducible fed-batch cultivations with Trichoderma
Externí odkaz:
https://doaj.org/article/d6a2bd1fba40476bb71046a6ab7e7b4f
Autor:
Mariana Gonzalez-Hernandez, Franziska Karola Kaiser, Imke Steffen, Malgorzata Ciurkiewicz, Geert van Amerongen, Ronen Tchelet, Mark Emalfarb, Markku Saloheimo, Marilyn G. Wiebe, Marika Vitikainen, Irina C. Albulescu, Berend-Jan Bosch, Wolfgang Baumgärtner, Bart L. Haagmans, Albert D. M. E. Osterhaus
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe emergency use of vaccines has been the most efficient way to control the coronavirus disease 19 (COVID-19) pandemic. However, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern has reduce
Externí odkaz:
https://doaj.org/article/7fffac3c6eae4c2f8eddf91dd7e3b855
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-16 (2020)
Abstract Background Two marine fungi, a Trichoderma sp. and a Coniochaeta sp., which can grow on d-galacturonic acid and pectin, were selected as hosts to engineer for mucic acid production, assessing the suitability of marine fungi for production of
Externí odkaz:
https://doaj.org/article/00123566811e46b8b50afcfa4fdb1fd6
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0236822 (2020)
Various marine fungi have been shown to produce interesting, bioactive compounds, but scaling up the production of these compounds can be challenging, particularly because little is generally known about how the producing organisms grow. Here we asse
Externí odkaz:
https://doaj.org/article/f9687303240642c985df0524c132ce78
Autor:
Gabor Keresztes, Mark Baer, Mark R. Alfenito, Theo C. Verwoerd, Andriy Kovalchuk, Marilyn G. Wiebe, Tor Kristian Andersen, Markku Saloheimo, Ronen Tchelet, Richard Kensinger, Gunnveig Grødeland, Mark Emalfarb
Publikováno v:
Vaccines, Vol 10, Iss 2, p 148 (2022)
(1) Influenza viruses constantly change and evade prior immune responses, forcing seasonal re-vaccinations with updated vaccines. Current FDA-approved vaccine manufacturing technologies are too slow and/or expensive to quickly adapt to mid-season cha
Externí odkaz:
https://doaj.org/article/c17043cd61fe4ba9908412126993a4c3
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-11 (2017)
Abstract Background Bioconversion of d-galacturonic acid to galactaric (mucic) acid has previously been carried out in small scale (50–1000 mL) cultures, which produce tens of grams of galactaric acid. To obtain larger amounts of biologically produ
Externí odkaz:
https://doaj.org/article/8fdf03abf03a4d45a85295542202e52b
Autor:
Kari Koivuranta, Sandra Castillo, Paula Jouhten, Laura Ruohonen, Merja Penttilä, Marilyn G. Wiebe
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Mitochondrial pyruvate dehydrogenase (PDH) is important in the production of lipids in oleaginous yeast, but other yeast may bypass the mitochondria (PDH bypass), converting pyruvate in the cytosol to acetaldehyde, then acetate and acetyl CoA which i
Externí odkaz:
https://doaj.org/article/7c2490b42794452981930723f4cb28a3
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195329 (2018)
Euglena gracilis, a photosynthetic protist, produces protein, unsaturated fatty acids, wax esters, and a unique β-1,3-glucan called paramylon, along with other valuable compounds. The cell composition of E. gracilis was investigated in this study to
Externí odkaz:
https://doaj.org/article/9da488f84c6a4437ab0bc0a3019efd49
Autor:
Mie Bech Lukassen, Wagma Saei, Teis Esben Sondergaard, Anu Tamminen, Abhishek Kumar, Frank Kempken, Marilyn G. Wiebe, Jens Laurids Sørensen
Publikováno v:
Marine Drugs, Vol 13, Iss 7, Pp 4331-4343 (2015)
Scopularide A is a promising potent anticancer lipopeptide isolated from a marine derived Scopulariopsis brevicaulis strain. The compound consists of a reduced carbon chain (3-hydroxy-methyldecanoyl) attached to five amino acids (glycine, l-valine, d
Externí odkaz:
https://doaj.org/article/5919f781579d48758a620b0fca98bffb
Publikováno v:
Marine Drugs, Vol 13, Iss 7, Pp 3992-4005 (2015)
Increased interest in marine resources has led to increased screening of marine fungi for novel bioactive compounds and considerable effort is being invested in discovering these metabolites. For compound discovery, small-scale cultures are adequate,
Externí odkaz:
https://doaj.org/article/77e058c449f6481289089e73e5d554d4