Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marilyn Dubois"'
Autor:
Morgan Bérard, Razan Sheta, Sarah Malvaut, Raquel Rodriguez-Aller, Maxime Teixeira, Walid Idi, Roxanne Turmel, Melanie Alpaugh, Marilyn Dubois, Manel Dahmene, Charleen Salesse, Jérôme Lamontagne-Proulx, Marie-Kim St-Pierre, Omid Tavassoly, Wen Luo, Esther Del Cid-Pellitero, Raza Qazi, Jae-Woong Jeong, Thomas M Durcan, Luc Vallières, Marie-Eve Tremblay, Denis Soulet, Martin Lévesque, Francesca Cicchetti, Edward A Fon, Armen Saghatelyan, Abid Oueslati
Publikováno v:
PLoS Biology, Vol 20, Iss 3, p e3001578 (2022)
Neurodegenerative disorders refer to a group of diseases commonly associated with abnormal protein accumulation and aggregation in the central nervous system. However, the exact role of protein aggregation in the pathophysiology of these disorders re
Externí odkaz:
https://doaj.org/article/2345db5e865f4420afb480af79493bdb
Autor:
Morgan Bérard, Razan Sheta, Sarah Malvaut, Raquel Rodriguez-Aller, Maxime Teixeira, Walid Idi, Roxanne Turmel, Melanie Alpaugh, Marilyn Dubois, Manel Dahmene, Charleen Salesse, Jérôme Lamontagne-Proulx, Marie-Kim St-Pierre, Omid Tavassoly, Wen Luo, Esther Del Cid-Pellitero, Raza Qazi, Jae-Woong Jeong, Thomas M. Durcan, Luc Vallières, Marie-Eve Tremblay, Denis Soulet, Martin Lévesque, Francesca Cicchetti, Edward A. Fon, Armen Saghatelyan, Abid Oueslati
Publikováno v:
PLoS biology. 20(3)
Neurodegenerative disorders refer to a group of diseases commonly associated with abnormal protein accumulation and aggregation in the central nervous system. However, the exact role of protein aggregation in the pathophysiology of these disorders re
Autor:
Martin Lévesque, Edward A. Fon, Francesca Cicchetti, Thomas M. Durcan, Charleen Salesse, Sarah Malvaut, Omid Tavassoly, Marilyn Dubois, Walid Idi, Jérôme Lamontagne-Proulx, Raquel Rodriguez-Aller, Wen Luo, Abid Oueslati, Marie-Ève Tremblay, Maxime Teixeira, Morgan Bérard, Raza Qazi, Marie-Kim St-Pierre, Jae-Woong Jeong, Esther Del Cid-Pellitero, Razan Sheta, Denis Soulet, Roxanne Turmel, Manel Dahmene, Melanie Alpaugh, Luc Vallières, Armen Saghatelyan
Publikováno v:
SSRN Electronic Journal.
α-Synuclein (α-syn) aggregation into insoluble deposits, referred to as Lewy bodies (LBs), is the paramount pathological hallmark of Parkinson’s disease (PD) and related α-synucleinopathies. However, the mechanism by which these aggregates contr
Autor:
Oscar Andrés Moreno-Ramos, Rajeshwar Awatramani, Yoon Seok Kim, Maite Azcorra, Navid Nouri, Lief E. Fenno, Giuliana Caronia-Brown, Zachary Gaertner, Jean-François Poulin, Daniel A. Dombeck, Yong Chao Ma, Marilyn Dubois, Francesca Cicchetti, Charu Ramakrishnan, Serafin Gatica, Karl Deisseroth, Milagros Pereira Luppi
Publikováno v:
Cell reports
SUMMARY Dopamine (DA) neurons in the ventral tier of the substantia nigra pars compacta (SNc) degenerate prominently in Parkinson’s disease, while those in the dorsal tier are relatively spared. Defining the molecular, functional, and developmental
Autor:
Jasna Kriz, Marilyn Dubois, Dany Arsenault, Antonio Cicchetti, Martine Saint-Pierre, Francesca Cicchetti, Benoit Aubé, Melanie Alpaugh
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Deep brain stimulation (DBS) has been used in clinical settings for many years despite a paucity of knowledge related to the anatomical and functional substrates that lead to benefits and/or side-effects in various disease contexts. In order to maxim
Autor:
Morgan Bérard, Charleen Salesse, Jérôme Lamontagne-Proulx, Jae-Woong Jeong, Manel Dahmene, Roxanne Turmel, Melanie Alpaugh, Marilyn Dubois, Omid Tavassoly, Marcos Schaan Profes, Sarah Malvaut, Abid Oueslati, Raza Qazi, Armen Saghatelyan, Edward A. Fon, Francesca Cicchetti, Martin Lévesque, Razan Sheta, Denis Soulet
Publikováno v:
SSRN Electronic Journal.
α-synuclein (α-syn) aggregation into insoluble deposits, referred to as Lewy bodies (LBs) is the paramount pathological hallmark of Parkinson’s disease and related α-synucleinopathies. However, how these aggregates affect neuronal homeostasis le
Autor:
Janelle Drouin-Ouellet, Jasna Kriz, Antonio Cicchetti, Francesca Cicchetti, Marilyn Dubois, Martine Saint-Pierre, Roger A. Barker, Dany Arsenault, Petros Petrou
Publikováno v:
The Journal of Physiology. 593:2257-2278
Deep brain stimulation (DBS) is used to treat a number of neurological conditions and is currently being tested to intervene in neuropsychiatric conditions. However, a better understanding of how it works would ensure that side effects could be minim