Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marilyn C. Cato"'
Autor:
Jessica Waninger-Saroni, Kelly M. Larimore, Paul D. Kirchhoff, Joseph Y. Cheung, Kristoff T. Homan, Osvaldo Cruz-Rodríguez, Helen V. Waldschmidt, John J.G. Tesmer, Marilyn C. Cato, Jianliang Song, Alessandro Cannavo, Scott D. Larsen, Walter J. Koch
Publikováno v:
Journal of Medicinal Chemistry. 59:3793-3807
G protein-coupled receptors (GPCRs) are central to many physiological processes. Regulation of this superfamily of receptors is controlled by GPCR kinases (GRKs), some of which have been implicated in heart failure. GSK180736A, developed as a Rho-ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61d76f3119d086fa1097fdb72ed05ea
https://doi.org/10.1021/acs.jmedchem.5b02000
https://doi.org/10.1021/acs.jmedchem.5b02000
Autor:
Alessandro Cannavo, Joseph Y. Cheung, Walter J. Koch, Xin-Qiu Yao, Jianliang Song, Marilyn C. Cato, Helen V. Waldschmidt, Renee Bouley, John J.G. Tesmer, Scott D. Larsen
Publikováno v:
Molecular pharmacology. 92(6)
G protein–coupled receptor kinases (GRKs) phosphorylate activated receptors to promote arrestin binding, decoupling from heterotrimeric G proteins, and internalization. GRK2 and GRK5 are overexpressed in the failing heart and thus have become thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4cc5e56b252a193dd0b4933a77334d
https://pubmed.ncbi.nlm.nih.gov/29070696
https://pubmed.ncbi.nlm.nih.gov/29070696
Autor:
Marilyn C. Cato, Osvaldo Cruz-Rodríguez, Alessandro Cannavo, Walter J. Koch, Joseph Y. Cheung, Kristoff T. Homan, Scott D. Larsen, Helen V. Waldschmidt, Jianliang Song, Michael W. Wilson, John J.G. Tesmer
In heart failure, the β-adrenergic receptors (βARs) become desensitized and uncoupled from heterotrimeric G proteins. This process is initiated by G protein-coupled receptor kinases (GRKs), some of which are upregulated in the failing heart, making
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc95ad4ec5e668167ab16bfdd42fafb
http://hdl.handle.net/11588/732638
http://hdl.handle.net/11588/732638
Autor:
Jianliang Song, Alessandro Cannavo, Michael W. Wilson, Scott D. Larsen, Walter J. Koch, Helen V. Waldschmidt, John J.G. Tesmer, Joseph Y. Cheung, Marilyn C. Cato, Osvaldo Cruz-Rodríguez, Kristoff T. Homan
Publikováno v:
Journal of Medicinal Chemistry. 62:5920-5920
G protein-coupled receptors (GPCRs) are central to many physiological processes. Regulation of this superfamily of receptors is controlled by GPCR kinases (GRKs), some of which have been implicated in heart failure. GSK180736A, developed as a Rho-ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c3d19f03142925d75d070becb0f52e
https://doi.org/10.1021/acs.jmedchem.9b00844
https://doi.org/10.1021/acs.jmedchem.9b00844
Autor:
William S. Barge, Jordan A. Magarik, Truc M. Le, Eunsook Lee, Dejan Milatovic, Marilyn C. Cato, João Rocha, Michael Aschner, Marshall L. Summar, Gary Cunningham, Marcelo Farina, Haiyan Jiang
Publikováno v:
NeuroToxicology. 32:518-525
γ-Glutamylcysteine (γ-GC) is an intermediate molecule of the glutathione (GSH) synthesis pathway. In the present study, we tested the hypothesis that γ-GC pretreatment in cultured astrocytes and neurons protects against hydrogen peroxide (H(2)O(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e0113c5a42b2df544b7b488d862ee2
https://doi.org/10.1016/j.neuro.2010.11.008
https://doi.org/10.1016/j.neuro.2010.11.008
a b s t r a c t Schizosaccharomyces pombe contains two paralogous proteins, Mag1 and Mag2, related to the helixhairpin-helix (HhH) superfamily of alkylpurine DNA glycosylases from yeast and bacteria. Phylogenetic analysis of related proteins from fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28632ebfb789293326db9d21caaf00e4
https://europepmc.org/articles/PMC4008723/
https://europepmc.org/articles/PMC4008723/