Výsledky vyhledávání - "Marilyn A. Isbell"

Anti-proliferative effect of a putative endocannabinoid, 2-arachidonylglyceryl ether in prostate carcinoma cells

Autor: Marilyn A. Isbell, Jeffrey Woodliff, Michael P. Endsley, William B. Campbell, Kasem Nithipatikom

Publikováno v: Prostaglandins & Other Lipid Mediators. 94:34-43

Endocannabinoids (ECs), anandamide (AEA) and 2-arachidonoylglycerol (2-AG), inhibit proliferation of carcinoma cells. Several enzymes hydrolyze ECs to reduce endogenous EC concentrations and produce eicosanoids that promote cell growth. In this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4fc118955269f7d98d30dd3c27583ed
https://doi.org/10.1016/j.prostaglandins.2010.12.002

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Effects of selective inhibition of cytochrome P-450 ω-hydroxylases and ischemic preconditioning in myocardial protection

Autor: William B. Campbell, Kasem Nithipatikom, Michael P. Endsley, John R. Falck, Jeannine Moore, Marilyn A. Isbell, Garrett J. Gross

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 290:H500-H505

Cytochrome P-450 (CYP) ω-hydroxylases and their arachidonic acid (AA) metabolite, 20-hydroxyeicosatetraenoic acid (20-HETE), produce a detrimental effect on ischemia-reperfusion injury in canine hearts, and the inhibition of CYP ω-hydroxylases mark

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee23f17178f4e7f605b7562ed1cbfdc4
https://doi.org/10.1152/ajpheart.00918.2005

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Elevated 12- and 20-hydroxyeicosatetraenoic acid in urine of patients with prostatic diseases

Autor: Marilyn A. Isbell, William B. Campbell, Kasem Nithipatikom, William A. See

Publikováno v: Cancer Letters. 233:219-225

The role of eicosanoids (metabolites of arachidonic acid) in prostate diseases is receiving increased attention. We investigated the relationship between the concentrations of urinary free acids of 12- and 20-hydroxyeicosatetraenoic acids (12- and 20

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e252507157d83f5f07733d2495a9b307
https://doi.org/10.1016/j.canlet.2005.03.025

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Cytochrome and arachidonic acid metabolites: Role in myocardial ischemia/reperfusion injury revisited

Autor: Eric R. Gross, Jeannine Moore, Marilyn A. Isbell, Kasem Nithipatikom, John R. Falck, Garrett J. Gross

Publikováno v: Cardiovascular Research. 68:18-25

Ischemia-reperfusion of the heart and other organs results in the accumulation of unesterified arachidonic acid (AA) via the action of membrane-bound phospholipases, primarily phospholipase A2. AA can be metabolized by the classical cyclooxygenase (C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1d4274326fca890e6bcdd0428d11b9a
https://doi.org/10.1016/j.cardiores.2005.06.007

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A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells

Autor: Marilyn A. Isbell, Bruce D. Hammock, William B. Campbell, Kasem Nithipatikom, Michael P. Endsley, Craig E. Wheelock

Publikováno v: Biochemical and Biophysical Research Communications. 332:1028-1033

Endogenous 2-arachidonoylglycerol (2-AG) inhibits invasion of androgen-independent prostate cancer cells. Blocking cellular hydrolysis of 2-AG to increase its endogenous concentration results in a decrease in cell invasion. A series of compounds cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b962bf49b8eedc3db50a70d5ad7f65c
https://doi.org/10.1016/j.bbrc.2005.05.049

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2-Arachidonoylglycerol

Autor: Marilyn A. Isbell, William B. Campbell, Kasem Nithipatikom, Michael P. Endsley, Yoshiki Iwamoto, John R. Falck, Cecilia J. Hillard

Publikováno v: Cancer Research. 64:8826-8830

Endocannabinoids have been implicated in cancer. Increasing endogenous 2-arachidonoylglycerol (2-AG) by blocking its metabolism inhibits invasion of androgen-independent prostate cancer (PC-3 and DU-145) cells. Noladin ether (a stable 2-AG analog) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3713e63daa5fa91beb109f0de758fd52
https://doi.org/10.1158/0008-5472.can-04-3136

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12-Lipoxygenase in Opioid-Induced Delayed Cardioprotection

Autor: Richard A. Bundey, Anna K. Hsu, Ryan M. Fryer, Leonard O.V. Eusebi, Eric R. Gross, Kasem Nithipatikom, Garrett J. Gross, Steven R. Gullans, Marilyn A. Isbell, Hemal H. Patel, Roderick V. Jensen, Paul A. Insel

Publikováno v: Circulation Research. 92:676-682

12-Lipoxygenase (12-LO) has been shown to be a factor in acute ischemic preconditioning (IPC) in the isolated rat heart; however, no studies have been reported in delayed PC. We characterized the role of 12-LO in an intact rat model of delayed PC ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b420d1dc82693b6916e30a052dacff2c
https://doi.org/10.1161/01.res.0000065167.52922.f6

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[Untitled]

Autor: Paul F. Lindholm, Marilyn A. Isbell, Sushma Kaul, Kasem Nithipatikom, Andre Kajdacsy-Balla, William B. Campell

Publikováno v: Clinical and Experimental Metastasis. 19:593-601

The PC-3 Low Invasive cells and the PC-3 High Invasive cells were used to investigate the correlation of the COX-2 expression and its arachidonic acid metabolites, prostaglandins, with their invasiveness through Matrigel® using a Boyden chamber assa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::184d6898a9f9140ef32e0c6852b88a9f
https://doi.org/10.1023/a:1020915914376

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