Zobrazeno 1 - 10
of 578
pro vyhledávání: '"Marilyn A Huestis"'
Autor:
Jose M Trigo, Alexandra Soliman, Lena C Quilty, Benedikt Fischer, Jürgen Rehm, Peter Selby, Allan J Barnes, Marilyn A Huestis, Tony P George, David L Streiner, Gregory Staios, Bernard Le Foll
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190768 (2018)
BackgroundThe current lack of pharmacological treatments for cannabis use disorder (CUD) warrants novel approaches and further investigation of promising pharmacotherapy. We previously showed that nabiximols (27 mg/ml Δ9-tetrahydrocannabinol (THC)/
Externí odkaz:
https://doaj.org/article/2df88c1827024f69864d2fc5090ef3bd
Autor:
Hiroto Kuwabara, Stephen J Heishman, James R Brasic, Carlo Contoreggi, Nicola Cascella, Kristen M Mackowick, Richard Taylor, Olivier Rousset, William Willis, Marilyn A Huestis, Marta Concheiro, Gary Wand, Dean F Wong, Nora D Volkow
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113694 (2014)
The rewarding effects of nicotine are associated with activation of nicotine receptors. However, there is increasing evidence that the endogenous opioid system is involved in nicotine's rewarding effects. We employed PET imaging with [11C]carfentanil
Externí odkaz:
https://doaj.org/article/f479d7c7614a4c96b3cf3dc1c06a8f27
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Although kratom use has been part of life for centuries in Southeast Asia, the availability and use of kratom in the United States (US) increased substantially since the early 2000s when there was little information on kratom pharmacology, use patter
Externí odkaz:
https://doaj.org/article/ff5cc3822e04402d84320d51d9e8e0a6
Autor:
Paolo Zanotti-Fregonara, Jussi Hirvonen, Chul Hyoung Lyoo, Sami S Zoghbi, Denise Rallis-Frutos, Marilyn A Huestis, Cheryl Morse, Victor W Pike, Robert B Innis
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60231 (2013)
Population-based input function (PBIF) may be a valid alternative to full blood sampling for quantitative PET imaging. PBIF is typically validated by comparing its quantification results with those obtained via arterial sampling. However, for PBIF to
Externí odkaz:
https://doaj.org/article/6ffb6eb8614d4689afca69770de0dcc4
Autor:
Wendy M Bosker, Erin L Karschner, Dayong Lee, Robert S Goodwin, Jussi Hirvonen, Robert B Innis, Eef L Theunissen, Kim P C Kuypers, Marilyn A Huestis, Johannes G Ramaekers
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53127 (2013)
The present study assessed psychomotor function in chronic, daily cannabis smokers during 3 weeks continuously monitored abstinence on a secure research unit. We hypothesized that psychomotor performance would improve during abstinence of chronic, da
Externí odkaz:
https://doaj.org/article/e5c24cdfb6ed4b8cbf760f9e300aa6be
Autor:
Chun-Ting Lee, Jia Chen, Teruo Hayashi, Shang-Yi Tsai, Joseph F Sanchez, Stacie L Errico, Rose Amable, Tsung-Ping Su, Ross H Lowe, Marilyn A Huestis, James Shen, Kevin G Becker, Herbert M Geller, William J Freed
Publikováno v:
PLoS Medicine, Vol 5, Iss 6, p e117 (2008)
BackgroundPrenatal exposure of the developing brain to cocaine causes morphological and behavioral abnormalities. Recent studies indicate that cocaine-induced proliferation inhibition and/or apoptosis in neural progenitor cells may play a pivotal rol
Externí odkaz:
https://doaj.org/article/1cc76f6cf38841e19f75293f85a2b3c6
Autor:
Elin Lehrmann, Carlo Colantuoni, Amy Deep-Soboslay, Kevin G Becker, Ross Lowe, Marilyn A Huestis, Thomas M Hyde, Joel E Kleinman, William J Freed
Publikováno v:
PLoS ONE, Vol 1, p e114 (2006)
A major goal of drug abuse research is to identify and understand drug-induced changes in brain function that are common to many or all drugs of abuse. As these may underlie drug dependence and addiction, the purpose of the present study was to exami
Externí odkaz:
https://doaj.org/article/b210f8a81be348b48465fae0a808997f
Autor:
Jack E. Henningfield, Marek C. Chawarski, Albert Garcia-Romeu, Oliver Grundmann, Norsyifa Harun, Zurina Hassan, Christopher R. McCurdy, Lance R. McMahon, Abhisheak Sharma, Mohammed Shoaib, Darshan Singh, Kirsten E. Smith, Marc T. Swogger, Balasingam Vicknasingam, Zachary Walsh, Daniel W. Wang, Marilyn A. Huestis
Publikováno v:
Drug and Alcohol Dependence Reports, Vol 7, Iss , Pp 100142- (2023)
Externí odkaz:
https://doaj.org/article/a7c79b48354f4a0286f0c6a3017b0ed1
Publikováno v:
Molecules, Vol 29, Iss 5, p 984 (2024)
Kratom leaves, consumed by millions worldwide as tea or ground leaf powder, contain multiple alkaloids, with mitragynine being the most abundant and responsible for most effects. Mitragynine is a partial µ-opioid receptor agonist and competitive ant
Externí odkaz:
https://doaj.org/article/f7497e1fcd4a4a9187a4741fbc9beb21
Autor:
Alexandre Barcia Godoi, Natalícia de Jesus Antunes, Kelly Francisco Cunha, Aline Franco Martins, Marilyn A. Huestis, Jose Luiz Costa
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 257 (2024)
New Psychoactive Substances (NPSs) are defined as a group of substances produced from molecular modifications of traditional drugs. These molecules represent a public health problem since information about their metabolites and toxicity is poorly und
Externí odkaz:
https://doaj.org/article/65a069d6958f4435b3bd8b325ea762d4