Výsledky vyhledávání - "Marilyn, De Graeve"

Akademický článek

Novel Alkaloids from Marine Actinobacteria: Discovery and Characterization

Autor: Anne-Sofie De Rop, Jeltien Rombaut, Thomas Willems, Marilyn De Graeve, Lynn Vanhaecke, Paco Hulpiau, Sofie L. De Maeseneire, Maarten L. De Mol, Wim K. Soetaert

Publikováno v: Marine Drugs, Vol 20, Iss 1, p 6 (2021)

The marine environment is an excellent resource for natural products with therapeutic potential. Its microbial inhabitants, often associated with other marine organisms, are specialized in the synthesis of bioactive secondary metabolites. Similar to

Externí odkaz: https://doaj.org/article/c1cdbbc58b3a4b8195c0cf2d873c17b5

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Point-of-care applicable metabotyping using biofluid-specific electrospun MetaSAMP®s directly amenable to ambient ionization mass spectrometry

Autor: Margot De Spiegeleer, Vera Plekhova, Jozefien Geltmeyer, Ella Schoolaert, Beata Pomian, Varoon Singh, Kathleen Wijnant, Kimberly Dewindt, Volter Paukku, Alexander De Loof, Inge Gies, Nathalie Michels, Stefaan De Henauw, Marilyn De Graeve, Karen De Clerck, Lynn Vanhaecke

While rapid analysis of the human biofluid metabolome is now possible using ambient ionization mass spectrometry (AIMS), these procedures are hampered by in-source matrix effects and reduced sample stability impeding metabolome coverage while remaini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64810af9488f99e6a4277b68d450f2ca
https://doi.org/10.26434/chemrxiv-2023-lthxl-v2

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A Dual UHPLC-HRMS-Based Fecal Metabolomics and Lipidomics Analysis and Automated Data Processing Pipeline for Comprehen-sive Gut Phenotyping

Autor: Pablo Vangeenderhuysen, Jasmien Van Arnhem, Beata Pomian, Marilyn De Graeve, Lindsey De Commer, Gwen Falony, Jeroen Raes, Alexandra Zhernakova, Jingyuan Fu, Lieselot Y. Hemeryck, Lynn Vanhaecke

In recent years, feces has surfaced as the matrix of choice for investigating the gut microbiome-health axis because of its non-invasive sampling and the unique reflection it offers of an individual’s lifestyle. In cohort studies where the number o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bbd54a39691ff1fb9cffad11a8627b
https://doi.org/10.26434/chemrxiv-2023-5f252

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Comprehensive metabolomics reveals correlation between sophorolipid biosynthesis and autophagy

Autor: Sven Dierickx, Maximilien Souvereyns, Sophie L.K.W. Roelants, Marilyn De Graeve, Lieven Van Meulebroek, Sofie L. De Maeseneire, Wim K.G. Soetaert, Lynn Vanhaecke

Publikováno v: NEW BIOTECHNOLOGY
Dierickx, S, Souvereyns, M, Roelants, S L K W, De Graeve, M, Van Meulebroek, L, De Maeseneire, S L, Soetaert, W K G & Vanhaecke, L 2023, ' Comprehensive metabolomics reveals correlation between sophorolipid biosynthesis and autophagy ', BMC Biotechnology, vol. 75, pp. 1-12 . https://doi.org/10.1016/j.nbt.2023.02.002

Sophorolipids are biobased and biodegradable glycolipid surface-active agents contributing to the shift from petroleum to biobased surfactants, associated with clear environmental benefits. However, their production cost is currently too high to allo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c9b31409aece6e414bc0abd78aa217
https://biblio.ugent.be/publication/01H16YQSAB0E2PGXJS09JMB42T/file/01H190V6T3BRH69AGS932YNNBC

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Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow’s milk allergy

Autor: Ellen De Paepe, Vera Plekhova, Pablo Vangeenderhuysen, Nele Baeck, Dominique Bullens, Tania Claeys, Marilyn De Graeve, Kristien Kamoen, Anneleen Notebaert, Tom Van de Wiele, Wim Van Den Broeck, Koen Vanlede, Myriam Van Winckel, Lars Vereecke, Eric Cox, Lynn Vanhaecke

Understanding the underlying mechanisms behind IgE-mediated cow’s milk allergy (IgE-CMA) is imperative for the discovery of novel biomarkers and the design of innovative treatment and prevention strategies. Here, we report data on the gut microbiom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50ffe8b1f7b210249cef9941f086a38e
https://doi.org/10.21203/rs.3.rs-2381024/v1

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Novel Alkaloids from Marine Actinobacteria: Discovery and Characterization

Autor: Thomas Willems, Marilyn De Graeve, Jeltien Rombaut, Paco Hulpiau, Sofie De Maeseneire, Lynn Vanhaecke, Wim Soetaert, Anne-Sofie De Rop, Maarten De Mol

Publikováno v: Marine Drugs
MARINE DRUGS
Marine Drugs, Vol 20, Iss 6, p 6 (2022)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660a359b95620be4abf909edbcb06246
http://europepmc.org/articles/PMC8777666

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Akademický článek

Increasing Uniformity of Biosurfactant Production in Starmerella bombicola via the Expression of Chimeric Cytochrome P450s

Autor: Robin Geys, Marilyn De Graeve, Sofie Lodens, Jeroen Van Malderen, Christophe Lemmens, Margaux De Smet, Stein Mincke, Inge N. A. Van Bogaert, Christian Stevens, Sofie L. De Maeseneire, Sophie L. K. W. Roelants, Wim K. G. Soetaert

Publikováno v: Colloids and Interfaces, Vol 2, Iss 4, p 42 (2018)

Sophorolipids are one of the best known microbial biosurfactants and are produced by several yeast species. The best studied producer is Starmerella bombicola, a non-pathogenic yeast associated in nature with bumblebees. Sophorolipids are built up of

Externí odkaz: https://doaj.org/article/7d504980b21a4f45a470eea42a349682

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Rapid ex vivo molecular fingerprinting of biofluids using laser-assisted rapid evaporative ionization mass spectrometry

Autor: Ellen De Paepe, Emma Van de Walle, Simon J S Cameron, Vera Plekhova, Margot De Spiegeleer, Alvaro Perdones-Montero, Lieven Van Meulebroek, Zoltan Takats, Marilyn De Graeve, Lynn Vanhaecke

Publikováno v: Plekhova, V, Van Meulebroek, L, De Graeve, M, Perdones-Montero, A, De Spiegeleer, M, De Paepe, E, Van de Walle, E, Takats, Z, Cameron, S J S & Vanhaecke, L 2021, ' Rapid ex vivo molecular fingerprinting of biofluids using laser-assisted rapid evaporative ionization mass spectrometry ', Nature Protocols . https://doi.org/10.1038/s41596-021-00580-8

Of the many metabolites involved in any clinical condition, only a narrow range of biomarkers is currently being used in the clinical setting. A key to personalized medicine would be to extend this range. Metabolic fingerprinting provides a more comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6511004bb645eab619d029e7f038122
https://pure.qub.ac.uk/en/publications/rapid-ex-vivo-molecular-fingerprinting-of-biofluids-using-laserassisted-rapid-evaporative-ionization-mass-spectrometry(9d0f14a0-dbda-4a36-ac22-aad00edb8d00).html

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Palmitic Acid Sophorolipid Biosurfactant: From Self-Assembled Fibrillar Network (SAFiN) To Hydrogels with Fast Recovery

Autor: Javier Pérez, Niki Baccile, Ghazi Ben Messaoud, Patrick Le Griel, Sophie Roelants, Robin Geys, Marilyn De Graeve, Nathan Cowieson, Wim Soetaert

Publikováno v: Philosophical Transactions of the Royal Society of London. A (1887–1895)
Philosophical Transactions of the Royal Society of London. A (1887–1895), Royal Society, The, In press, ⟨10.1098/rsta.2020.0343⟩
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2021, ⟨10.1098/rsta.2020.0343⟩

Nanofibers are an interesting phase into which amphiphilic molecules can self-assemble. Described for a large number of synthetic lipids, they were seldom reported for natural lipids like microbial amphiphiles, known as biosurfactants. In this work,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334829224cd9de71856d7be47fe9fa5d
https://hal.archives-ouvertes.fr/hal-03147266

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