Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marilou, Tetard"'
Autor:
Barbara Baro-Sastre, Chi Yong Kim, Carrie Lin, Angel K. Kongsomboonvech, Marilou Tetard, Nichole D. Salinas, Niraj H. Tolia, Elizabeth S. Egan
Publikováno v:
bioRxiv
The malaria parasitePlasmodium falciparuminvades and replicates asexually within human erythrocytes. CD44 expressed on erythrocytes was previously identified as an important host factor forP. falciparuminfection through a forward genetic screen, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6784fbcf83056387edc5f2a269bd0a3
https://europepmc.org/articles/PMC10120705/
https://europepmc.org/articles/PMC10120705/
Publikováno v:
Current Opinion in Microbiology. 70:102221
Targeting critical host factors is an emerging concept in the treatment of infectious diseases. As obligate pathogens of erythrocytes, the Plasmodium spp. parasites that cause malaria must exploit erythroid host factors for their survival. However, o
Autor:
Christian N, Nguetse, Natasha, Purington, Emily R, Ebel, Bikash, Shakya, Marilou, Tetard, Peter G, Kremsner, Thirumalaisamy P, Velavan, Elizabeth S, Egan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The clinical presentation of Plasmodium falciparum malaria as severe versus uncomplicated is influenced by host genetic factors. Recently, a gain-of-function mutation in the mechanosensitive ion channel PIEZO1 was shown to protect mice a