Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marilin S. Koch"'
Autor:
Marilin S. Koch, Mykola Zdioruk, Michal O. Nowicki, Alec M. Griffith, Estuardo Aguilar-Cordova, Laura K. Aguilar, Brian W. Guzik, Francesca Barone, Paul Peter Tak, Katharina Schregel, Michael S. Hoetker, James A. Lederer, E. Antonio Chiocca, Ghazaleh Tabatabai, Sean E. Lawler
Publikováno v:
Molecular Therapy: Oncolytics, Vol 26, Iss , Pp 275-288 (2022)
CAN-2409 is a replication-deficient adenovirus encoding herpes simplex virus (HSV) thymidine kinase (tk) currently in clinical trials for treatment of glioblastoma. The expression of tk in transduced cancer cells results in conversion of the pro-drug
Externí odkaz:
https://doaj.org/article/d1ff12c2b9db4d9895906f9830d6592e
Autor:
Marilin S. Koch, Mykola Zdioruk, Michal O. Nowicki, Michael S. Hoetker, Zachary T. Herbert, Francesca Barone, Paul P. Tak, E. Antonio Chiocca, Ghazaleh Tabatabai, Sean E. Lawler
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
RationaleCAN-2409 is a locally delivered oncolytic therapy, which results in vaccination against the injected tumor. CAN-2409 consists of a non-replicating adenovirus armed with the Herpes virus thymidine kinase, which metabolizes ganciclovir into a
Externí odkaz:
https://doaj.org/article/059541d246d54f58b9384666b90522ef
Autor:
Mykola Zdioruk, Jorge-Luis Jimenez-Macias, Michal Oskar Nowicki, Katherine E. Manz, Kurt D. Pennell, Marilin S. Koch, Tomer Finkelberg, Bin Wu, Paul Boucher, Yuji Takeda, Weiyi Li, Raziye Piranlioglu, Alexander L. Ling, E. Antonio Chiocca, Sean E. Lawler
Publikováno v:
Cell Reports Medicine. 4:101019
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0495a2c1e8c67077c510fcd0abb75491
https://doi.org/10.1016/j.xcrm.2023.101019
https://doi.org/10.1016/j.xcrm.2023.101019
Autor:
Marilin S Koch, Mykola Zdioruk, Michal O Nowicki, Alec M Griffith, Estuardo Aguilar, Laura K Aguilar, Brian W Guzik, Francesca Barone, Paul P Tak, Ghazaleh Tabatabai, James A Lederer, E Antonio Chiocca, Sean Lawler
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
BackgroundIntratumoral viral oncolytic immunotherapy is a promising new approach for the treatment of a variety of solid cancers. CAN-2409 is a replication-deficient adenovirus that delivers herpes simplex virus thymidine kinase to cancer cells, resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b8be09b80beec58beda1af9d511f57
https://pubmed.ncbi.nlm.nih.gov/35017150
https://pubmed.ncbi.nlm.nih.gov/35017150
Autor:
Francesca Barone, Paul P Tak, Sean Lawler, James A Lederer, Marilin S Koch, Mykola Zdioruk, Michal O Nowicki, Alec M Griffith, Estuardo Aguilar, Laura K Aguilar, Brian W Guzik, E Antonio Chiocca
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/06519b4a8e9e4394bfe536ab62aa59b5