Výsledky vyhledávání - "Marilia S. Costa"

Akademický článek

Desenvolvimento e validação de metodologia para a certificação da pureza enantiomérica do Efavirenz

Autor: CECÍLIA SUMIE FUZITA WATANABE, QUEZIA B. CASS, NÚBIA BOECHAT, MARILIA S. COSTA, PAULA S. SÁ, MARIA L. G. AZEVEDO, LEANDRO S. BARBOSA

Publikováno v: Revista Uningá, Vol 2, Iss 1 (2004)

Uma metodologia simples, por CLAE (Cromatografia Líquida de Alta Eficiência) quiral, foi desenvolvida e validada para a determinação da pureza enantiomérica do efavirenz. A metodologia foi desenvolvida utilizando-se uma coluna quiral com fase tr

Externí odkaz: https://doaj.org/article/62a62d733c2f4db59f514fb443fb369a

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Novel 1,2,3-Triazole Derivatives for Use against Mycobacterium tuberculosis H37Rv (ATCC 27294) Strain

Autor: Fernando de C. da Silva, Nubia Boechat, Maria C.S. Lourenço, Priscila R. C. Martins, Gerson P. da Silva, Antoniana U. Krettli, Nathalia V da Silva, Mônica M. Bastos, Brunno M Teixeira, Flávio A. F. M. Bezerra, Maria de Lourdes G. Ferreira, Carolina C. P. Costa, Angelo C. Pinto, Anna Caroline Campos Aguiar, Sabrina B. Ferreira, Vitor F. Ferreira, Marilia S. Costa, Ane Louise S Camilo

Publikováno v: Journal of Medicinal Chemistry. 54:5988-5999

The purpose of this study was to prepare various 4-substituted N-phenyl-1,2,3-triazole derivatives using click chemistry. The derivatives were screened in vitro for antimicrobial activity against Mycobacterium tuberculosis strain H37Rv (ATCC 27294) u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7714dddfa9eccdabd620753be2fa8d4c
https://doi.org/10.1021/jm2003624

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Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents

Autor: Sabrina Baptista Ferreira, Warner B. Kover, Marcelo Genestra, Vitor F. Ferreira, Marilia S. Costa, Marilene M. Canto-Cavalheiro, Rômulo José Soares Bezerra, Nubia Boechat

Publikováno v: European Journal of Medicinal Chemistry. 42:1388-1395

Several compounds of great pharmacological interest contain the triazole and imidazole rings. In order to find new drugs with antileishmanial activity we have synthesized and evaluated new imidazole and triazole compounds carrying either the carbalde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683cf1d53c64e2843c90327cabc023c1
https://doi.org/10.1016/j.ejmech.2007.02.020

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Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1,2,3-triazole derivatives

Autor: Érica A. Rangel, Vitor F. Ferreira, Helena Carla Castro, Marilia S. Costa, Alessandra Mendonça Teles de Souza, Nubia Boechat, Solange M. S. V. Wardell, Ivan Neves Junior, Fernando de C. da Silva, Carlos Rangel Rodrigues, Maria C.S. Lourenço

Publikováno v: Bioorganic & Medicinal Chemistry. 14:8644-8653

The aim of this work was to describe the synthesis, the in vitro anti-Mycobacterium tuberculosis profile, and the structure–activity relationship (SAR) study of new N-substituted-phenyl-1,2,3-triazole-4-carbaldehydes (3a–l). The reactions of arom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496e179668c48066a58defe3e12a4501
https://doi.org/10.1016/j.bmc.2006.08.019

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4-Difluoromethyl-1-(2,5-dimethoxyphenyl)-1H-1,2,3-triazole

Autor: Vitor F. Ferreira, Janet M. S. Skakle, Solange M. S. V. Wardell, Nubia Boechat, Marilia S. Costa

Publikováno v: Acta Crystallographica Section E Structure Reports Online. 62:o2048-o2050

In the title compound, C11H11F2N3O2, the aryl and triazole rings are both planar, but at an angle of 45.27 (4)° to each other.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::951227d6fbc779a71b4e95b0d93cb43d
https://doi.org/10.1107/s1600536806013924

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4-Difluoromethyl-1-(4-methylphenyl)-1H-1,2,3-triazole

Autor: Vitor F. Ferreira, Janet M. S. Skakle, Nubia Boechat, Marilia S. Costa, Solange M. S. V. Wardell

Publikováno v: Acta Crystallographica Section E Structure Reports Online. 62:o1925-o1927

In the crystal structure of the title compound, C10H9F2N3, weak hydrogen bonding involving the triazole and difluoromethyl groups leads to the formation of chains along [010]. The benzene and triazole rings are essentially coplanar, with an angle of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5299d4779d85196f1298eea95831a64
https://doi.org/10.1107/s1600536806013286

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Synthesis and evaluation of 1-alkyl-4-phenyl-[1,2,3]-triazole derivatives as antimycobacterial agent

Autor: Gilmar Conte, Vitor F. Ferreira, Hugo Gallardo, Fernando R. Bryk, Marilia S. Costa, Maria C.S. Lourenço

Publikováno v: Journal of the Brazilian Chemical Society v.18 n.6 2007
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 18, Issue: 6, Pages: 1285-1291, Published: 2007

Fourteen small molar mass 1-alkyl-4-phenyl-[1,2,3]-triazole derivatives were prepared using a straightforward and efficient method for the regioselective synthesis of [1,2,3]-triazoles and the compounds were screened for antimycobacterial activity ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ba072f3a34fbee6f11d7c3eb8cefad
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000600027

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Three ethyl 5-amino-1-aryl-1H-imidazole-4-carboxylates: hydrogen-bonded supramolecular structures in one, two and three dimensions

Autor: Marilia S. Costa, Vitor F. Ferreira, Christopher Glidewell, John N. Low, Solange M. S. V. Wardell, Nubia Boechat

Publikováno v: Acta crystallographica. Section C, Crystal structure communications. 63(Pt 1)

The molecules of ethyl 5-amino-1-(4-cyanophenyl)-1H-imidazole-4-carboxylate, C13H12N4O2, are linked into a chain of alternating R(2)2(10) and R(4)4(34) rings by a combination of N-H...N and C-H...N hydrogen bonds. In ethyl 5-amino-1-(4-chlorophenyl)-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d776575ac7dc985eb6f5bd3495ca40
https://pubmed.ncbi.nlm.nih.gov/17206050

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Métodos de obtenção e aplicações sintéticas de tiazóis, uma importante classe de compostos heterocíclicos

Autor: Marcus V. N. de Souza, Jorge S. Mendonça, Fabiane Ramos Rebello, Sabrina B. Ferreira, Marilia S. Costa

Publikováno v: Química Nova v.28 n.1 2005
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Volume: 28, Issue: 1, Pages: 78-83, Published: FEB 2005

Thiazoles comprise an important class of heterocyclic compounds present in many potent biologically active molecules. This heterocyclic ring also shows various applications in organic synthesis to obtain new compounds. This paper presents different m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4ded5765a8e2c5cef0ebfa58adf6ff
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422005000100016

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Fragmentation studies of tetrahydropyridocarbazole derivatives by EI, ESI-MS/MS and FAB

Autor: Gilberto A. Romeiro, Marilia S. Costa, Vitor F. Ferreira, José Walkimar de M. Carneiro, Alexandre M. Joaquim, Bernd Kammerer

Publikováno v: ResearcherID

Four tetrahydropyridocarbazole derivatives were analysed by different mass spectrometry techniques: electrospray ionization, fast atom bombardment and by low and high resolution 70 eV electron ionization. Retro Diels Alder is the main fragmentation p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42beac6e9f407dbe8b206f5ca7bb09ed

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