Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Marilena P Etna"'
Autor:
Martina Severa, Marilena Paola Etna, Emanuele Andreano, Daniela Ricci, Giada Cairo, Stefano Fiore, Andrea Canitano, Andrea Cara, Paola Stefanelli, Rino Rappuoli, Anna Teresa Palamara, Eliana Marina Coccia
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109703- (2024)
Summary: Monoclonal antibodies (mAb) targeting the SARS-CoV-2 Spike (S) glycoprotein have been exploited for the treatment of severe COVID-19. In this study, we evaluated the immune-regulatory features of two neutralizing anti-S mAbs (nAbs), named J0
Externí odkaz:
https://doaj.org/article/36527309821042d4bfdb8dadf3e37891
Autor:
Martina Severa, Daniela Ricci, Marilena Paola Etna, Marzia Facchini, Simona Puzelli, Giorgio Fedele, Egidio Iorio, Giada Cairo, Sara Castrechini, Valentina Ungari, Marco Iannetta, Pasqualina Leone, Mattea Chirico, Maria Elena Pisanu, Barbara Bottazzi, Livia Benedetti, Michela Sali, Remo Bartolomucci, Stefano Balducci, Cecilia Garlanda, Paola Stefanelli, Antonietta Spadea, Anna Teresa Palamara, Eliana Marina Coccia
Publikováno v:
Vaccines, Vol 12, Iss 9, p 1050 (2024)
In this pilot study, a multi-parametric analysis comparing immune responses in sera of adult healthy subjects (HS) or people with type 2 diabetes mellitus (T2D) undergoing the single or simultaneous administration of mRNA-based COVID-19 and cellular
Externí odkaz:
https://doaj.org/article/2a84fb822358407a9d7d96df4ccdf1cc
Autor:
Martina Severa, Fabiana Rizzo, Alessandro Sinigaglia, Daniela Ricci, Marilena Paola Etna, Gaia Cola, Doriana Landi, Maria Chiara Buscarinu, Catia Valdarchi, Giovanni Ristori, Silvia Riccetti, Chiara Piubelli, Pierangela Palmerini, Antonio Rosato, Federico Gobbi, Stefano Balducci, Girolama Alessandra Marfia, Marco Salvetti, Luisa Barzon, Eliana Marina Coccia
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 3, Pp n/a-n/a (2023)
Abstract Objectives The very rapidly approved mRNA‐based vaccines against SARS‐CoV‐2 spike glycoprotein, including Pfizer‐BioNTech BNT162b2, are effective in protecting from severe coronavirus disease 2019 (COVID‐19) in immunocompetent popu
Externí odkaz:
https://doaj.org/article/12ea6285304b4b618c2023708673a137
Autor:
Alessandra Zevini, Enrico Palermo, Daniele Di Carlo, Magdalini Alexandridi, Serena Rinaldo, Alessio Paone, Francesca Cutruzzola, Marilena P. Etna, Eliana M. Coccia, David Olagnier, John Hiscott
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Dendritic cells (DCs) are important mediators of the induction and regulation of adaptive immune responses following microbial infection and inflammation. Sensing environmental danger signals including viruses, microbial products, or inflammatory sti
Externí odkaz:
https://doaj.org/article/d66c57fed7be4788a8aa5072998ed0b6
Autor:
Martina Severa, Roberta A Diotti, Marilena P Etna, Fabiana Rizzo, Stefano Fiore, Daniela Ricci, Marco Iannetta, Alessandro Sinigaglia, Alessandra Lodi, Nicasio Mancini, Elena Criscuolo, Massimo Clementi, Massimo Andreoni, Stefano Balducci, Luisa Barzon, Paola Stefanelli, Nicola Clementi, Eliana M Coccia
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009878 (2021)
SARS-CoV-2 fine-tunes the interferon (IFN)-induced antiviral responses, which play a key role in preventing coronavirus disease 2019 (COVID-19) progression. Indeed, critically ill patients show an impaired type I IFN response accompanied by elevated
Externí odkaz:
https://doaj.org/article/ad30e9e2c6c54cdfbb29689d53a04fe4
Autor:
Marilena P. Etna, Martina Severa, Valerio Licursi, Manuela Pardini, Melania Cruciani, Fabiana Rizzo, Elena Giacomini, Gianfranco Macchia, Orazio Palumbo, Raffaella Stallone, Massimo Carella, Mark Livingstone, Rodolfo Negri, Sandra Pellegrini, Eliana M. Coccia
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In human primary dendritic cells (DC) rapamycin—an autophagy inducer and protein synthesis inhibitor—overcomes the autophagy block induced by Mycobacterium tuberculosis (Mtb) and promotes a Th1 response via IL-12 secretion. Here, the immunostimul
Externí odkaz:
https://doaj.org/article/eb748d7cd1c049debd23f736020b2119
Autor:
Marilena P Etna, Aurora Signorazzi, Daniela Ricci, Martina Severa, Fabiana Rizzo, Elena Giacomini, Andrea Gaggioli, Isabelle Bekeredjian-Ding, Anke Huckriede, Eliana M Coccia
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009505 (2021)
The Tick-borne encephalitis virus (TBEV) causes different disease symptoms varying from asymptomatic infection to severe encephalitis and meningitis suggesting a crucial role of the human host immune system in determining the fate of the infection. T
Externí odkaz:
https://doaj.org/article/750e33173eeb4ede945877d605a1d8de
Autor:
Melania Cruciani, Silvia Sandini, Marilena P. Etna, Elena Giacomini, Romina Camilli, Martina Severa, Fabiana Rizzo, Fabio Bagnoli, John Hiscott, Eliana M. Coccia
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Understanding Staphylococcus aureus (S. aureus)–host immune system interaction is crucial to meet the tremendous medical need associated with this life-threatening bacterial infection. Given the crucial role of dendritic cells (DC) in dictating imm
Externí odkaz:
https://doaj.org/article/2af1652bc6c74455961e079ff76ba09b
Autor:
Aurora Signorazzi, Jeroen L. A. Pennings, Marilena P. Etna, Malou Noya, Eliana M. Coccia, Anke Huckriede
Publikováno v:
Vaccines, Vol 9, Iss 6, p 664 (2021)
Tick-borne encephalitis virus (TBEV) infection can lead to inflammation of the central nervous system. The disease can be effectively prevented by whole inactivated virus vaccines. Here, we investigated the innate immune profile induced in vitro by t
Externí odkaz:
https://doaj.org/article/d4df25421400459187d17fa7866e5bee
Autor:
Marilena P Etna, Alessandro Sinigaglia, Angela Grassi, Elena Giacomini, Alessandra Romagnoli, Manuela Pardini, Martina Severa, Melania Cruciani, Fabiana Rizzo, Eleni Anastasiadou, Barbara Di Camillo, Luisa Barzon, Gian Maria Fimia, Riccardo Manganelli, Eliana M Coccia
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006790 (2018)
Autophagy is a primordial eukaryotic pathway, which provides the immune system with multiple mechanisms for the elimination of invading pathogens including Mycobacterium tuberculosis (Mtb). As a consequence, Mtb has evolved different strategies to hi
Externí odkaz:
https://doaj.org/article/fe31d479545c4217b1e5c8195af409a8