Výsledky vyhledávání - "Marilena Fotino"

Familial Pulmonary Hypertension: Immunogenetic Findings in Four Caucasian Kindreds

Autor: Robyn J. Barst, Marilena Fotino, Jane H. Morse

Publikováno v: American Review of Respiratory Disease. 145:787-792

A postulated association between primary pulmonary hypertension (PPH) and autoimmune diseases prompted this study. To see if autoantibodies and an association with the major histocompatibility locus (MHC) accompany the familial form of pulmonary hype

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9da95605806f3a2c3b1e1d8e80a7add
https://doi.org/10.1164/ajrccm/145.4_pt_1.787

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Direct characterization of human T cells in pemphigus vulgaris reveals elevated autoantigen-specific Th2 activity in association with active disease

Autor: Carina Rizzo, Selwyn Chow, Marilena Fotino, Amy Spizuoco, Y. Zhang, Animesh A. Sinha

Publikováno v: Clinical and experimental dermatology. 30(5)

Summary Pemphigus vulgaris (PV) is a blistering skin disorder mediated by autoantibodies targeting the epidermal adhesion molecule desmoglein 3 (Dsg3). As Th2-associated cytokines are necessary for directing antibody production, it is hypothesized th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0423958b0a3498b80d4572d43a92841
https://pubmed.ncbi.nlm.nih.gov/16045688

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Disease relevant HLA class II alleles isolated by genotypic, haplotypic, and sequence analysis in North American Caucasians with pemphigus vulgaris

Autor: Erica H. Lee, Derek Gordon, Selwyn Chow, Marilena Fotino, Animesh A. Sinha, Daniela Nguyen, Yun Zhang, Robert Dionisio, Amy Spizuoco, Yasmin Pirani, Katherine A. Lendas

Publikováno v: Human immunology. 67(1-2)

Early studies of genetic susceptibility to pemphigus vulgaris (PV) showed associations between human leukocyte antigen (HLA) DR4 and DR6 and disease. The emergence of DNA sequencing techniques has implicated numerous DRB1 and DQB1 loci in various pop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3415a28703cedf39e9543698f7dd2626
https://pubmed.ncbi.nlm.nih.gov/16698434

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HLA-independent heterogeneity of CD8+ T cell responses to MAGE-3, Melan-A/MART-1, gp100, tyrosinase, MC1R, and TRP-2 in vaccine-treated melanoma patients

Autor: Sandra R. Reynolds, Esteban Celis, Alessandro Sette, Ruth Oratz, Richard L. Shapiro, Dean Johnston, Marilena Fotino, Jean-Claude Bystryn

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(12)

An important element in melanoma vaccine construction is to identify peptides from melanoma-associated Ags that have immunogenic potential in humans and are recognized by CD8+ T cells in vivo. To identify such peptides, we evaluated HLA-A*02+ melanom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1a08956642ed4b1b4c83b24a1996f6
https://pubmed.ncbi.nlm.nih.gov/9862732

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Impaired fc-mediated mononuclear phagocyte system clearance in HLA-DR2 and MT1-positive healthy young adults

Autor: Jane E. Salmon, Marilena Fotino, Allan Gibofsky, Robert P. Kimberly

Publikováno v: The Journal of Experimental Medicine

Normal individuals with an HLA haplotype containing either DR2, MT1, or B8/DR3 are more likely to have abnormally prolonged Fc receptor-mediated mononuclear phagocyte system (MPS) clearance of IgG-sensitized autologous erythrocytes than their normal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363c8d8bf54787aab0bc1953118c0950
https://doi.org/10.1084/jem.157.5.1698

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