Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marilena Elpidorou"'
Autor:
Ioannis D. Kyrochristos, Georgios K. Glantzounis, Anna Goussia, Alexia Eliades, Achilleas Achilleos, Kyriakos Tsangaras, Irene Hadjidemetriou, Marilena Elpidorou, Marios Ioannides, George Koumbaris, Michail Mitsis, Philippos C. Patsalis, Dimitrios Roukos
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionThe mechanisms underlying high drug resistance and relapse rates after multi-modal treatment in patients with colorectal cancer (CRC) and liver metastasis (LM) remain poorly understood.ObjectiveWe evaluate the potential translational impl
Externí odkaz:
https://doaj.org/article/6c2e9e360b214662b6d27ac42404d714
Autor:
Ian Carr, Christopher Watson, Morag Raynor, Marilena Elpidorou, Ummey Hany, Laura Crinnon, Eamonn Sheridan, Alexander Markham, James Poulter, David Bonthron
Rare autosomal recessive diseases are a major cause of mortality and morbidity. They occur more frequently in individuals with consanguineous parents, in which case the pathogenic variants are often located within regions of genetic identity by desce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc62664ac7aa7f7c91376e996c9596cd
https://doi.org/10.22541/au.165933904.43435894/v1
https://doi.org/10.22541/au.165933904.43435894/v1
Autor:
Marilena Elpidorou, James A. Poulter, Katarzyna Szymanska, Wia Baron, Katrin Junger, Karsten Boldt, Marius Ueffing, Lydia Green, John H. Livingston, Eammon G. Sheridan, Colin A. Johnson
Publikováno v:
European journal of human genetics : EJHG, 860-864. Nature Publishing Group
STARTPAGE=860;ENDPAGE=864;ISSN=1018-4813;TITLE=European journal of human genetics : EJHG
STARTPAGE=860;ENDPAGE=864;ISSN=1018-4813;TITLE=European journal of human genetics : EJHG
Leukodystrophies are a heterogenous group of genetic disorders, characterised by abnormal development of cerebral white matter. Pelizaeus-Merzbacher disease is caused by mutations in PLP1, encoding major myelin-resident protein required for myelin sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e59a536c23af23127344e8ded39e3e9
https://eprints.whiterose.ac.uk/184118/1/Elpidorou_et_al-2022-European_Journal_of_Human_Genetics.pdf
https://eprints.whiterose.ac.uk/184118/1/Elpidorou_et_al-2022-European_Journal_of_Human_Genetics.pdf
Autor:
Georgios K. Glantzounis, Philippos C. Patsalis, Marios Ioannides, Ioannis D Kyrochristos, Irene Hadjidemetriou, Kyriakos Tsangaras, Anna Goussia, Marilena Elpidorou, George Koumbaris, Michail Mitsis, Achilleas Achilleos, Alexia Eliades, Dimitrios H Roukos
Publikováno v:
Frontiers in Oncology. 12
PurposeThe mechanisms underlying high drug resistance and relapse rates after multi-modal treatment in patients with colorectal cancer (CRC) and liver metastasis (LM) remain poorly understood. We evaluate the potential translational implications of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1b572014f123a49863a03eca21c8a4
https://doi.org/10.3389/fonc.2022.855463
https://doi.org/10.3389/fonc.2022.855463
Autor:
Emma Hobson, James A. Poulter, Eamonn Sheridan, Sunayna Best, Colin A. Johnson, Marilena Elpidorou, Verity L. Hartill
BackgroundThe HERC2 gene encodes a 527 kDa E3 ubiquitin protein ligase that has key roles in cell cycle regulation, spindle formation during mitosis, mitochondrial functions and DNA damage responses. It has essential roles during embryonic developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ebe4cbb5945408b9d27d60a25cac32
https://eprints.whiterose.ac.uk/160583/8/jmedgenet-2020-106873.full.pdf
https://eprints.whiterose.ac.uk/160583/8/jmedgenet-2020-106873.full.pdf
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Doxycycline has anti-tumour effects in a range of tumour systems. The aims of this study were to define the role mitochondria play in this process and examine the potential of doxycycline in combination with gemcitabine. We studied the adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb9700d6fe05e5a2eefe5ab31b51ae4
http://europepmc.org/articles/PMC7063048
http://europepmc.org/articles/PMC7063048
Autor:
Marilena, Elpidorou, Sunayna, Best, James A, Poulter, Verity, Hartill, Emma, Hobson, Eamonn, Sheridan, Colin A, Johnson
Publikováno v:
Journal of medical genetics. 58(5)
TheWe ascertained a consanguineous family with a presumed autosomal recessive severe neurodevelopmental disorder that leads to paediatric lethality. In affected individuals, we identified a homozygousThis study extends the genotype-phenotype correlat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa98ed83b6fd59d507af4efdcd57428b
https://pubmed.ncbi.nlm.nih.gov/32571899
https://pubmed.ncbi.nlm.nih.gov/32571899
Publikováno v:
Neuro Oncol
Glioblastoma (GBM) is an incurable brain cancer because, despite aggressive standard treatment (consisting of surgery, radiation and Temozolomide chemotherapy), 100% of tumours recur. GBM tumours are characterised by significant intratumour heterogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afe5ae1ea6e8a76cbc9aede50ce886e
https://europepmc.org/articles/PMC6789674/
https://europepmc.org/articles/PMC6789674/