Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Marilda Souza Goncalves"'
Autor:
Joelma Figueiredo Menezes, Magda Oliveira Seixas Carvalho, Larissa Carneiro Rocha, Felipe Miranda dos Santos, Elisângela Vitória Adorno, Cyntia Cajado de Souza, Rayra Pereira Santiago, Caroline Conceição da Guarda, Rodrigo Mota de Oliveira, Camylla Vilas Boas Figueiredo, Suéllen Pinheiro Carvalho, Sètondji Cocou Modeste Alexandre Yahouédéhou, Luciana Magalhães Fiuza, Corynne Stéphanie Ahouefa Adanho, Thassila Nogueira Pitanga, Isa Menezes Lyra, Valma Maria Lopes Nascimento, Alberto Augusto Noronha-Dutra, Marilda Souza Goncalves
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Sickle cell disease (SCD) patients often exhibit a dyslipidemic sub-phenotype. Paraoxonase 1 (PON 1) is a serum glycoprotein associated with the high-density lipoproteins cholesterol (HDL-C), and variability in PON1 activity depends on the P
Externí odkaz:
https://doaj.org/article/d3ca186186fb49ce9f36b6457163e292
Autor:
Joelma Santana dos Santos Neres, Sètondji Cocou Modeste Alexandre Yahouédéhou, Marilda Souza Goncalves
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 857 (2023)
Inconsistent therapeutic responses have been observed among patients with sickle cell anemia (SCA) undergoing hydroxyurea (HU) following the adoption of the standardized protocol. Moreover, this treatment regimen necessitates a prolonged period to re
Externí odkaz:
https://doaj.org/article/982c6b2130074231b328d2832e8e0914
Autor:
Corynne Stéphanie Ahouéfa Adanho, Sètondji Cocou Modeste Alexandre Yahouédéhou, Sânzio Silva Santana, Camilo Vieira, Rayra Pereira Santiago, Jeanne Machado de Santana, Thassila Nogueira Pitanga, Milena Magalhães Aleluia, Vítor Valério Maffili, Ivana Paula Ribeiro Leite, Dalila Luciola Zanette, Isa Menezes Lyra, Marilda Souza Goncalves
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundStroke is one of the highest complications of sickle-cell anemia (SCA). The Transcranial Doppler (TCD) has been adopted worldwide as a gold standard method for detecting alterations in the blood velocity in cerebral arteries. In this study,
Externí odkaz:
https://doaj.org/article/66b9dd24a8834b4fa171ac6e97b695b1
Autor:
Camylla Vilas Boas Figueiredo, Rayra Pereira Santiago, Caroline Conceição da Guarda, Rodrigo Mota Oliveira, Luciana Magalhães Fiuza, Sètondji Cocou Modeste Alexandre Yahouédéhou, Suéllen Pinheiro Carvalho, Joelma Santana Dos Santos Neres, Antonio Mateus de Jesus Oliveira, Cleverson Alves Fonseca, Valma Maria Lopes Nascimento, Isa Menezes Lyra, Milena Magalhães Aleluia, Marilda Souza Goncalves
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246067 (2021)
Priapism is a urologic emergency characterized by an uncontrolled, persistent and painful erection in the absence of sexual stimulation, which can lead to penile fibrosis and impotence. It is highly frequent in sickle cell disease (SCD) associated wi
Externí odkaz:
https://doaj.org/article/6de39a391e37471c8497f9ff44f767b3
Autor:
Sètondji Cocou Modeste Alexandre Yahouédéhou, Joelma Santana dos Santos Neres, Caroline Conceição da Guarda, Suellen Pinheiro Carvalho, Rayra Pereira Santiago, Camylla Vilas Boas Figueiredo, Luciana Magalhães Fiuza, Uche Samuel Ndidi, Rodrigo Mota de Oliveira, Cleverson Alves Fonseca, Valma Maria Lopes Nascimento, Larissa Carneiro Rocha, Corynne Stéphanie Ahouéfa Adanho, Tiago Santos Carvalho da Rocha, Elisângela Vitória Adorno, Marilda Souza Goncalves
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Differences in hydroxyurea response in sickle cell anemia may arise due to a series of factors with genetic factors appearing to be predominant. This study aims to investigate the effects of single nucleotide polymorphisms in genes encoding drug-meta
Externí odkaz:
https://doaj.org/article/3400dd841545442395b4388443304024
Autor:
Sânzio Silva Santana, Thassila Nogueira Pitanga, Jeanne Machado de Santana, Dalila Lucíola Zanette, Jamile de Jesus Vieira, Sètondji Cocou Modeste Alexandre Yahouédéhou, Corynne Stéphanie Ahouefa Adanho, Sayonara de Melo Viana, Nivea Farias Luz, Valeria Matos Borges, Marilda Souza Goncalves
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The excessive release of heme during hemolysis contributes to the severity of sickle cell anemia (SCA) by exacerbating hemoglobin S (HbS) autoxidation, inflammation and systemic tissue damage. The present study investigated the effect of hydroxyurea
Externí odkaz:
https://doaj.org/article/af61f05f2fee4385b7c0aad07605e624
Autor:
Caroline Conceição da Guarda, Sètondji Cocou Modeste Alexandre Yahouédéhou, Rayra Pereira Santiago, Joelma Santana Dos Santos Neres, Camila Felix de Lima Fernandes, Milena Magalhães Aleluia, Camylla Vilas Boas Figueiredo, Luciana Magalhães Fiuza, Suellen Pinheiro Carvalho, Rodrigo Mota de Oliveira, Cleverson Alves Fonseca, Uche Samuel Ndidi, Valma Maria Lopes Nascimento, Larissa Carneiro Rocha, Marilda Souza Goncalves
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228399 (2020)
Sickle cell disease (SCD) consists of a group of hemoglobinopathies in which individuals present highly variable clinical manifestations. Sickle cell anemia (SCA) is the most severe form, while SC hemoglobinopathy (HbSC) is thought to be milder. Thus
Externí odkaz:
https://doaj.org/article/f8190f50a51a4031937210902d2562a8
Autor:
Edvan do Carmo Santos, Gabriela Imbassahy Valentim Melo, Paulo Vinícius Bispo Santana, Idaiara Graziele Silva Quadros, Sètondji Cocou Modeste Alexandre Yahouédéhou, Caroline Conceição da Guarda, Rayra Pereira Santiago, Luciana Magalhães Fiuza, Suéllen Pinheiro Carvalho, Elisângela Vitória Adorno, Carla Martins Kaneto, Teresa Cristina Cardoso Fonseca, Marilda Souza Goncalves, Milena Magalhães Aleluia
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 317 (2022)
Sickle leg ulcers (SLU) are malleoli lesions with exuberant hemolytic pathophysiology. The microRNAs are potential genetic biomarkers for several pathologies. Thereby, we aimed to assess the expression of circulating miR-199a-5p, miR-144, and miR-126
Externí odkaz:
https://doaj.org/article/b88c870c3ae942d883d74d07733352bb
Autor:
Sètondji Cocou Modeste Alexandre Yahouédéhou, Caroline Conceição da Guarda, Camylla Vilas Boas Figueiredo, Rayra Pereira Santiago, Suellen Pinheiro Carvalho, Luciana Magalhães Fiuza, Uche Samuel Ndidi, Rodrigo Mota Oliveira, Magda Oliveira Seixas Carvalho, Valma Maria Lopes Nascimento, Larissa Carneiro Rocha, Isa Menezes Lyra, Elisângela Vitória Adorno, Marilda Souza Goncalves
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0218040 (2019)
This study investigated the effects of hydroxyurea (HU) on hematological, biochemical and inflammatory parameters in children with sickle cell anemia (SCA) in association with βS haplotype and α-thalassemia. We included 22 children with SCA who wer
Externí odkaz:
https://doaj.org/article/75c771f077224792836bb5f6109ca140
Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review
Autor:
Gustavo Marinho Miranda, Vitória Ohana Ramos e Santos, Jonatas Reis Bessa, Yanna C. F. Teles, Setondji Cocou Modeste Alexandre Yahouédéhou, Marilda Souza Goncalves, Jaime Ribeiro-Filho
Publikováno v:
Biomolecules, Vol 11, Iss 3, p 361 (2021)
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most widely used classes of medicines in the treatment of inflammation, fever, and pain. However, evidence has demonstrated that these drugs can induce significant toxicity. In the search
Externí odkaz:
https://doaj.org/article/b40e2bc7dfa14d8c820f612665f12fbb