Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Marila Cordeiro-Stone"'
Publikováno v:
Growth Regulation and Carcinogenesis ISBN: 9781351072328
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf1f609a52fc47afd0f9ff2fc215a5ac
https://doi.org/10.1201/9781351072328-12
https://doi.org/10.1201/9781351072328-12
Publikováno v:
Growth Regulation and Carcinogenesis ISBN: 9781351072328
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bdf06ac3f1c844d95cd544d60cc1e0a
https://doi.org/10.1201/9781351072328-13
https://doi.org/10.1201/9781351072328-13
Autor:
Paul D. Chastain, Joseph G. Ibrahim, Nancy E. Thomas, John J. McNulty, Marila Cordeiro-Stone, Yingchun Zhou, William K. Kaufmann, David L. Mitchell, Christopher D. Sproul, Eugene A. Gibbs-Flournoy, Shangbang Rao, Dennis A. Simpson, Craig C. Carson
The objective of this study was to assess potential functional attenuation or inactivation of the intra-S checkpoint during melanoma development. Proliferating cultures of skin melanocytes, fibroblasts and melanoma cell lines were exposed to increasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50432fb7a367764184657b4f806b074e
https://europepmc.org/articles/PMC4745347/
https://europepmc.org/articles/PMC4745347/
Autor:
Dennis A. Simpson, William K. Kaufmann, Marila Cordeiro-Stone, Gamze Karaca, Jacquelyn J. Bower, Yingchun Zhou
Publikováno v:
Oncogene
Topoisomerase IIalpha (topoIIalpha) is an essential mammalian enzyme that topologically modifies DNA and is required for chromosome segregation during mitosis. Previous research suggests that inhibition of topoII decatenatory activity triggers a G(2)
Autor:
Yingchun Zhou, Dennis A. Simpson, Sonnet J.H. Arlander, Marila Cordeiro-Stone, Tong Zhou, Jacquelyn J. Bower, William K. Kaufmann, Richard S. Paules
Publikováno v:
Cell Cycle. 9:1617-1628
The decatenation G2 checkpoint is proposed to delay cellular progression from G2 into mitosis when intertwined daughter chromatids are insufficiently decatenated. Previous studies indicated that the ATM- and Rad3-related (ATR) checkpoint kinase, but
Autor:
Dennis A. Simpson, Bo Chen, David L. Mitchell, Yingchun Zhou, Marila Cordeiro-Stone, William K. Kaufmann, Amritava Mitra
Publikováno v:
Cell Cycle. 8:1775-1787
After treatment with ultraviolet radiation (UV), human fibroblasts that express the HPV type 16 E6 oncoprotein display defects in repair of cyclobutane pyrimidine dimers, hypersensitivity to inactivation of clonogenic survival and an inability to sus
Autor:
Keziban Unsal-Kacmaz, Kathleen R. Nevis, Nana Nikolaishvili-Feinberg, G. Scott Jenkins, William K. Kaufmann, Marila Cordeiro-Stone, Cameron O. Scarlett, Dean P. Staus
Publikováno v:
Biochemistry. 47:4141-4150
This study investigated the requirement for ubiquitylation of PCNA at lysine 164 during polymerase eta-dependent translesion synthesis (TLS) of site-specific cis-syn cyclobutane thymine dimers (T (wedge)T). The in vitro assay recapitulated origin-dep
Autor:
Nancy E. Thomas, Glynis Scott, Zhi Liu, Pingping Qu, William K. Kaufmann, Dominic T. Moore, Yingchun Zhou, Marila Cordeiro-Stone, Kathleen R. Nevis, Jennifer Helms-Deaton, Tong Zhou, Dennis A. Simpson, Norman E. Sharpless, Janiel M. Shields, Joseph G. Ibrahim, Honglin Hao
Publikováno v:
Journal of Investigative Dermatology. 128(1):175-187
Defects in DNA damage responses may underlie genetic instability and malignant progression in melanoma. Cultures of normal human melanocytes (NHMs) and melanoma lines were analyzed to determine whether global patterns of gene expression could predict
Autor:
David G. Kaufman, Paul D. Chastain, Bruna P. Brylawski, Marila Cordeiro-Stone, Stephanie M. Cohen
Publikováno v:
Experimental and Molecular Pathology. 82:190-196
An origin of bidirectional DNA replication was mapped to the promoter of the FMR1 gene in human chromosome Xq27.3, which has been linked to the fragile X syndrome. This origin is adjacent to a CpG island and overlaps the site of expansion of the trip
Autor:
Paul D. Chastain, Bruna P. Brylawski, David G. Kaufman, Marila Cordeiro-Stone, Stephanie M. Cohen
Publikováno v:
Advances in Enzyme Regulation. 47:127-138
Our studies have revealed that replicating DNA is more vulnerable to adduction than is non-replicating DNA. Contrary to our expectations that the vulnerability to neoplastic transformation induced by carcinogens in synchronized cells would parallel t