Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Marilène Paquet"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 5, Pp 1627-1635 (2018)
Genetically engineered mouse models (GEMMs) are powerful tools by which to probe gene function in vivo, obtain insight into disease etiology, and identify modifiers of drug response. Increased sophistication of GEMMs has led to the design of tissue-s
Externí odkaz:
https://doaj.org/article/56c199e4afd447a19de5356776ec478e
Autor:
Sanaz Manteghi, Marie-Claude Gingras, Dmitri Kharitidi, Luc Galarneau, Maud Marques, Ming Yan, Regina Cencic, Francis Robert, Marilène Paquet, Michael Witcher, Jerry Pelletier, Arnim Pause
Publikováno v:
Cell Reports, Vol 15, Iss 9, Pp 1893-1900 (2016)
Endosomal sorting complexes required for transport (ESCRT) drive cell surface receptor degradation resulting in attenuation of oncogenic signaling and pointing to a tumor suppressor function. Here, we show that loss of function of an ESCRT protein (H
Externí odkaz:
https://doaj.org/article/20c7418fb9944e4c9e74f85af9af9e62
Autor:
Zubaidah M Ramdzan, Charles Vadnais, Ranjana Pal, Guillaume Vandal, Chantal Cadieux, Lam Leduy, Sayeh Davoudi, Laura Hulea, Lu Yao, Anthony N Karnezis, Marilène Paquet, David Dankort, Alain Nepveu
Publikováno v:
PLoS Biology, Vol 12, Iss 3, p e1001807 (2014)
The Cut homeobox 1 (CUX1) gene is a target of loss-of-heterozygosity in many cancers, yet elevated CUX1 expression is frequently observed and is associated with shorter disease-free survival. The dual role of CUX1 in cancer is illustrated by the fact
Externí odkaz:
https://doaj.org/article/547186a6161b417bae65cf422358505f
Autor:
Kyoko E Yuki, Megan M Eva, Etienne Richer, Dudley Chung, Marilène Paquet, Mathieu Cellier, François Canonne-Hergaux, Sophie Vaulont, Silvia M Vidal, Danielle Malo
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55331 (2013)
Salmonella, a ubiquitous Gram-negative intracellular bacterium, is a food borne pathogen that infects a broad range of hosts. Infection with Salmonella Typhimurium in mice is a broadly recognized experimental model resembling typhoid fever in humans.
Externí odkaz:
https://doaj.org/article/8908651da0e04fb08c0e9ccb4ff82572
Autor:
Alexandre Boyer, Jonathan R Yeh, Xiangfan Zhang, Marilène Paquet, Aurore Gaudin, Makoto C Nagano, Derek Boerboom
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29764 (2012)
Constitutive activation of the WNT signaling effector CTNNB1 (β-catenin) in the Sertoli cells of the Ctnnb1(tm1Mmt/+);Amhr2(tm3(cre)Bhr/+) mouse model results in progressive germ cell loss and sterility. In this study, we sought to determine if this
Externí odkaz:
https://doaj.org/article/83ebb6dfb3e047559682ebba2a55abe5
Autor:
Michel L. Tremblay, Marilène Paquet, Lloyd C. Trotman, Louis R. Bégin, Jody J. Haigh, Jacinthe Sirois, Eva Migon, Isabelle Aubry, Laurent Lessard, Valérie Vinette, Noriko Uetani, David P. Labbé
Supplementary Materials and Methods. Table S1: List of the different oligonucleotides used for mouse genotyping. Table S2: Phenotypic evaluation of prostate-specific PTP1B-overexpressing mice. Figure S1: Ptpn1 status does not alter the transition to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d4187cf43d71fb541eb857d7e17dfa
https://doi.org/10.1158/0008-5472.22409255
https://doi.org/10.1158/0008-5472.22409255
Autor:
Michel L. Tremblay, Marilène Paquet, Lloyd C. Trotman, Louis R. Bégin, Jody J. Haigh, Jacinthe Sirois, Eva Migon, Isabelle Aubry, Laurent Lessard, Valérie Vinette, Noriko Uetani, David P. Labbé
Supplementary Materials and Methods, Supplementary Table, Supplementary References and Supplementary Figures S1 to S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0eaccced29591db6ef4cf12fd6fca53
https://doi.org/10.1158/0008-5472.22409258.v1
https://doi.org/10.1158/0008-5472.22409258.v1
Autor:
Michel L. Tremblay, Marilène Paquet, Lloyd C. Trotman, Louis R. Bégin, Jody J. Haigh, Jacinthe Sirois, Eva Migon, Isabelle Aubry, Laurent Lessard, Valérie Vinette, Noriko Uetani, David P. Labbé
Diet affects the risk and progression of prostate cancer, but the interplay between diet and genetic alterations in this disease is not understood. Here we present genetic evidence in the mouse showing that prostate cancer progression driven by loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7784c025532018fc20affc6bfe1b7047
https://doi.org/10.1158/0008-5472.c.6507737.v1
https://doi.org/10.1158/0008-5472.c.6507737.v1
Autor:
Alain Nepveu, Marilène Paquet, Maria Drossos, Charles Vadnais, Lu Yao, Valérie Kedinger, Chantal Cadieux
Supplementary Tables 1-2, Figure 1 from Mouse Mammary Tumor Virus p75 and p110 CUX1 Transgenic Mice Develop Mammary Tumors of Various Histologic Types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54852e6e14d699659d735fb85460fb1f
https://doi.org/10.1158/0008-5472.22379270.v1
https://doi.org/10.1158/0008-5472.22379270.v1
Autor:
Alain Nepveu, Marilène Paquet, Maria Drossos, Charles Vadnais, Lu Yao, Valérie Kedinger, Chantal Cadieux
The p75 and p110 isoforms of the CUX1 homeodomain protein are overexpressed in breast tumors and cancer cell lines. To assess and compare the ability of these short CUX1 isoforms in driving mammary tumor development, we used site-specific transgenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b1dccd81947bc753ca703f6573e3f91
https://doi.org/10.1158/0008-5472.c.6499199.v1
https://doi.org/10.1158/0008-5472.c.6499199.v1