Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Mariko Takami"'
Autor:
Mariko Takami, Shinichiro Motohashi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Invariant natural killer T (iNKT) cells are a small subset of T lymphocytes that release large amounts of cytokines such as IFN-γ and exhibit cytotoxic activity upon activation, inducing strong anti-tumor effects. Harnessing the anti-tumor propertie
Externí odkaz:
https://doaj.org/article/450718aa1ed049a999d568f026b7aae4
Autor:
Yohei Kawasaki, Hideki Hanaoka, Takahiro Nakajima, Hidemi Suzuki, Takahide Toyoda, Toshiko Kamata, Kazuhisa Tanaka, Fumie Ihara, Mariko Takami, Takayuki Ikeuchi, Toshinori Nakayama, Ichiro Yoshino, Shinichiro Motohashi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Invariant natural killer T (iNKT) cells produce copious amounts of cytokines in response to specific glycolipid antigens such as α-galactosylceramide (αGalCer) presented by CD1d-expressing antigen-presenting cells (APCs), thus orchestrat
Externí odkaz:
https://doaj.org/article/9da3721b27c940288135a58c059a4cc5
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Invariant natural killer T (iNKT) cells produce copious amounts of cytokines in response to T-cell receptor (TCR) stimulation by recognizing antigens such as α-galactosylceramide (α-GalCer) presented on CD1d; thus, orchestrating other immune cells
Externí odkaz:
https://doaj.org/article/b9798a309cd54335bbb66a0f0438c1f9
Autor:
Shivanee Shah, Erin Lowery, Rudolf K Braun, Alicia Martin, Nick Huang, Melissa Medina, Periannan Sethupathi, Yoichi Seki, Mariko Takami, Kathryn Byrne, Christopher Wigfield, Robert B Love, Makio Iwashima
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38368 (2012)
The omentum is a sheet-like tissue attached to the greater curvature of the stomach and contains secondary lymphoid organs called milky spots. The omentum has been used for its healing potential for over 100 years by transposing the omental pedicle t
Externí odkaz:
https://doaj.org/article/e02315e563ef47819246b2b7f359c373
Autor:
Fumie Ihara, Takahide Toyoda, Toshinori Nakayama, Yasuo Iwadate, Masayoshi Kobayashi, Takahiro Aoki, Ryo Koyama-Nasu, Seiichiro Hirono, Ayaka Hara, Tomoo Matsutani, Mariko Takami, Shinichiro Motohashi
Publikováno v:
Cancer Immunology, Immunotherapy
Glioblastoma is the most common and aggressive type of brain tumor with high recurrence and fatality rates. Although various therapeutic strategies have been explored, there is currently no effective treatment for glioblastoma. Recently, the number o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ba16bb6bbcafde7e7b534233765abf
https://doi.org/10.1007/s00262-020-02742-1
https://doi.org/10.1007/s00262-020-02742-1
Autor:
Takahide Toyoda, Toshinori Nakayama, Moeko Hino, Naoki Shimojo, Kiwamu Motoyoshi, Mariko Takami, Kiyoshi Hirahara, Takahiro Aoki, Ryo Koyama-Nasu, Motoko Y. Kimura, Masahiro Kiuchi, Shinichiro Motohashi, Tomozumi Takatani, Ayaka Hara, Reona Okada, Ayana Ishii
Publikováno v:
Cancer Science
Invariant natural killer T (iNKT) cells are innate‐like CD1d‐restricted T cells that express the invariant T cell receptor (TCR) composed of Vα24 and Vβ11 in humans. iNKT cells specifically recognize glycolipid antigens such as α‐galactosylc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83cdae557706319b618ba6ca42798777
http://europepmc.org/articles/PMC7385353
http://europepmc.org/articles/PMC7385353
Autor:
Naohiro Sata, Mariko Takami, Koji Koinuma, Kenichi Oshiro, Alan Kawarai Lefor, Katsumi Kurihara, Misaki Matsumiya, Satoshi Inose, Hisanaga Horie
Publikováno v:
International Journal of Surgery Case Reports
Highlights • Internal hernias following laparoscopic colorectal resections are very rare. • A mesenteric defect of the left transverse colon might be at higher risk of an internal hernia on anatomic grounds. • We believe that a defect in the le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef7d617b0761a1769d325dc9d5c0795
http://europepmc.org/articles/PMC6920246
http://europepmc.org/articles/PMC6920246
Autor:
Yukiko Kanetsuna, Mariko Takami, Shigetoshi Yoshida, Takahide Toyoda, Toshiko Kamata, Ichiro Yoshino, Hiroko Yoshizawa, Tetsuo Sato, Seiichi Nobuyama, Shinichiro Motohashi, Yuichiro Takeshita, Fumie Ihara
Publikováno v:
Cancer Science
The role of immune checkpoint inhibitors in metastatic lung cancer has been established in recent years and the pretherapeutic profiles of the tumor microenvironment in responders have been increasingly reported. The role of salvage surgery and the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb46d25c690760f3ec7ac0b81cd3468d
https://doi.org/10.1111/cas.14222
https://doi.org/10.1111/cas.14222
Autor:
Fumie, Ihara, Daiju, Sakurai, Mariko, Takami, Toshiko, Kamata, Naoki, Kunii, Kazuki, Yamasaki, Tomohisa, Iinuma, Toshinori, Nakayama, Shinichiro, Motohashi, Yoshitaka, Okamoto
Publikováno v:
Cancer immunology, immunotherapy : CII. 68(12)
Due to the strong tumoricidal activities of activated natural killer T (NKT) cells, invariant NKT cell-based immunotherapy has shown promising clinical efficacy. However, suppressive factors, such as regulatory T cells (Tregs), may be obstacles in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3e6932b3b10480cddce9c8d1e6a03b4
https://pubmed.ncbi.nlm.nih.gov/31641795
https://pubmed.ncbi.nlm.nih.gov/31641795
Autor:
Ichiro Yoshino, Kazuaki Harada, Naoki Kunii, Shigetoshi Yoshida, Yuji Makita, Atsushi Horinaka, Mariko Takami, Naoko Mise, Fumie Ihara, Toshiko Kamata, Akane Suzuki, Shinichiro Motohashi, Toshinori Nakayama
Publikováno v:
Cancer Immunology, Immunotherapy
The role of invariant natural killer T (iNKT) cells in antitumor immunity has been studied extensively, and clinical trials in patients with advanced cancer have revealed a prolonged survival in some cases. In recent years, humanized blocking antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c3cf967824342211c9367a79c3597a
https://doi.org/10.1007/s00262-016-1901-y
https://doi.org/10.1007/s00262-016-1901-y