Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mariko Onishi"'
Autor:
Mariko Onishi, Kazuya Murata, Hideaki Matsuda, Masato Kondo, Kazuma Noguchi, Naoko Watanabe, Katsumasa Okamura
Publikováno v:
Phytotherapy Research. 27:212-217
Topical administration of Rosmarinus officinalis leaf extract (RO-ext, 2 mg/day/mouse) improved hair regrowth in C57BL/6NCrSlc mice that experienced hair regrowth interruption induced by testosterone treatment. In addition, RO-ext promoted hair growt
Autor:
Yui Sokuza, Mariko Onishi, Toshifumi Tsujiuchi, Kyoko Shimizu, Chiharu Mori, Tomoki Nishikawa, Mariko Saito, Eriko Sugata
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 638:133-138
Mutations in the mitochondrial DNA (mtDNA) displacement loop (D-loop) region were investigated to clarify the possible molecular mechanisms underlying the development of lung tumors induced by N-nitrosobis(2-hydroxypropyl)amine (BHP) in rats. Male Wi
Autor:
Kyoko Shimizu, Chiharu Mori, Eriko Sugata, Tomoki Nishikawa, Toshifumi Tsujiuchi, Yui Sokuza, Kanya Honoki, Mariko Onishi
Publikováno v:
Cancer Science. 98:1318-1322
The authors investigated the DNA methylation patterns of the E-cadherin, Connexin 26 (Cx26), Rassf1a and c-fos genes in the early phase of rat hepatocarcinogenesis induced by a choline-deficient L-amino acid-defined (CDAA) diet. Six-week-old F344 mal
Autor:
Hiromasa Fujii, Kyoko Shimizu, Mariko Onishi, Eriko Sugata, Toshifumi Tsujiuchi, Kanya Honoki
Publikováno v:
Biochemical and Biophysical Research Communications. 353:522-526
To determine if the Tslc1 gene is involved in pancreatic carcinogenesis, the expression level of Tslc1 and the DNA methylation status of its 5' upstream region were investigated in pancreatic duct adenocarcinomas (PDAs) induced in hamsters by N-nitro
Autor:
Mariko Onishi, Kanya Honoki, Toshifumi Tsujiuchi, Kyoko Shimizu, Eriko Sugata, Midori Yoshida, Mayumi Fujii
Publikováno v:
Journal of Toxicologic Pathology. 20:65-69
Epidermal growth factor receptor (EGFR), a receptor protein tyrosine kinase, is a transmembrane protein. Recent studies indicate that mutations in the gene encoding EGFR are present in several human cancers. To assess the involvement of these mutatio
Autor:
Tomoki Nishikawa, Yui Sokuza, Toshifumi Tsujiuchi, Toshio Mori, Mariko Onishi, Chiharu Mori, Mariko Saito
Publikováno v:
Journal of Toxicologic Pathology. 20:263-266
Mutations in the mitochondrial DNA (mtDNA) displacement loop (D-loop) region were investigated to clarify the possible molecular mechanisms underlying the development of hamster pancreatic tumors. Female Syrian golden hamsters received 30 mg/kg N-nit
Autor:
Michiko Shimomura, Yoshimitsu Katoh, Shunji Nagaoka, Mariko Onishi, Ichiro Shoji, Toru Takahashi
Publikováno v:
Journal for the Integrated Study of Dietary Habits. 17:16-22
Autor:
Nobuyuki Fukushima, Shinya Shano, Toshifumi Tsujiuchi, Kanya Honoki, Kyoko Shimizu, Mayumi Shigemura, Mariko Onishi
Publikováno v:
Journal of Toxicologic Pathology. 19:137-141
Lysophosphatidic acid (LPA) is a bioactive phospholipid that stimulates cell proliferation and migration, and protects cells from apoptosis. It interacts with at least three specific G protein-coupled transmembrane receptors, LPA1, LPA2 and LPA3. In
Autor:
Kazuya, Murata, Kazuma, Noguchi, Masato, Kondo, Mariko, Onishi, Naoko, Watanabe, Katsumasa, Okamura, Hideaki, Matsuda
Publikováno v:
Phytotherapy research : PTR. 27(2)
Topical administration of Rosmarinus officinalis leaf extract (RO-ext, 2 mg/day/mouse) improved hair regrowth in C57BL/6NCrSlc mice that experienced hair regrowth interruption induced by testosterone treatment. In addition, RO-ext promoted hair growt
Autor:
Katsumasa Okamura, Kazuya Murata, Masato Kondo, Kazuma Noguchi, Mariko Onishi, Hideaki Matsuda, Naoko Watanabe
Publikováno v:
Journal of natural medicines. 66(1)
Crude drugs expected to have an estrogenic effect were screened for their inhibitory activity on testosterone 5α-reductase. Testosterone 5α-reductase is an enzyme catalyzing the conversion of testosterone to dihydrotestosterone, which possesses hig