Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mariko Mariyama"'
Publikováno v:
Journal of Biological Chemistry. 269:26172-26177
The entire sequence of the human alpha 4(IV) collagen chain was determined from cDNA clones and polymerase chain reaction-amplified DNAs. The complete translation product has 1,690 amino acid residues and the processed alpha 4(IV) chain proper 1,652
Autor:
Sripad Gunwar, Eric G. Neilson, Raghuram Kalluri, Stephen T. Reeders, Jeanne C. Myers, Theodore M. Danoff, Mariko Mariyama, Mae Jane Sun, Billy G. Hudson
Publikováno v:
Journal of Biological Chemistry. 268:8402-8405
Type IV collagen has recently emerged as a family composed of five known chains (alpha 1-alpha 5), each of which contains a carboxyl-terminal noncollagenous domain (NC1) of approximately 230 amino acids. The NC1 domain of the alpha 3(IV) chain is the
Autor:
Mariko Mariyama, Billy G. Hudson, Stephen T. Reeders, Raghuram Kalluri, Milton E. Noelken, Sripad Gunwar
Publikováno v:
Kidney International. 43(1):135-139
Molecular characteristics of the Goodpasture autoantigen. Goodpasture syndrome is an autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary hemorrhage. The clinical manifestations are caused by autoantibodies that bind to a c
Publikováno v:
Neurological Research. 14:236-240
Point mutations in the transmembrane domain of c-erbB-2 gene in human brain tumours were studied by DNA amplification with the polymerase chain reaction method. Amplified gene fragments in M13 phage vector were cloned, and subsequent nucleotide seque
Publikováno v:
Journal of Biological Chemistry. 267:1253-1258
Renal basement membranes are believed to contain five distinct type IV collagens. An understanding of the specific roles of these collagens and the specificities of their interactions will be aided by knowledge of their comparative structures. Genes
Autor:
Stephen T. Reeders, Milton E. Noelken, Mariko Mariyama, Kurt E. Ebner, Billy G. Hudson, Raghuram Kalluri, Karen C. Morrison, Sripad Gunwar
Publikováno v:
Journal of Biological Chemistry. 266:24018-24024
The autoantibodies of patients with Goodpasture syndrome are primarily targeted to the noncollagenous (NC1) domain of the alpha 3(IV) chain of basement membrane collagen (Saus, J., Wieslander, J., Langeveld, J. P. M., Quinones, S., and Hudson, B. G.
Publikováno v:
Clinical Genetics. 48:162-163
Autor:
Yves Pirson, Cornelis H. Schröder, Stephen T. Reeders, Marie-Claire Gubler, Toshio Mochizuki, Henny H. Lemmink, Christine Verellen-Dumoulin, Belinda Chan, Mariko Mariyama, Corinne Antignac, Hubert J.M. Smeets
Publikováno v:
Nature genetics. 8(1)
Alport syndrome (AS) is an hereditary disease of basement membranes characterized by progressive renal failure and deafness. Changes in the glomerular basement membrane (GBM) in AS suggest that the type IV collagen matrix, the major structural compon
Publikováno v:
Genomics. 13(3)
Each type of basement membrane in man contains between two and five genetically distinct type IV collagens: α1(IV)–α5(IV). Genes for α1(IV), α2(IV), α3(IV), and α5(IV) have been isolated. We have recently isolated partial cDNAs for the fifth
Publikováno v:
Japanese Journal of Cancer Research : Gann
Point mutations at the 12th codon of c-Ki-ras in pancreatic cancer from Japanese patients were examined using the polymerase chain reaction, followed by cloning of the amplified gene fragments in pTZ phagemid and nucleotide sequence determination. Th