Zobrazeno 1 - 10
of 533
pro vyhledávání: '"Mariko Harada"'
Autor:
Sayaka Funabashi, Yu Kataoka, Mika Hori, Masatsune Ogura, Takahito Doi, Yoshiaki Morita, Eri Kiyoshige, Kunihiro Nishimura, Teruo Noguchi, Mariko Harada‐Shiba
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background The atherogenic characteristics of heterozygous familial hypercholesterolemia (HeFH) increase the risk of premature atherosclerotic cardiovascular disease including not only coronary artery disease but ischemic stroke. Asymptomatic intracr
Externí odkaz:
https://doaj.org/article/5ff075290af440fdbd969ffd83c464e8
Autor:
Chisato Terada, Kaho Oh, Ryutaro Tsubaki, Bun Chan, Nozomi Aibara, Kaname Ohyama, Masa-Aki Shibata, Takehiko Wada, Mariko Harada-Shiba, Asako Yamayoshi, Tsuyoshi Yamamoto
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Off-target interactions between antisense oligonucleotides (ASOs) with state-of-the-art modifications and biological components still pose clinical safety liabilities. To mitigate a broad spectrum of off-target interactions and enhance the s
Externí odkaz:
https://doaj.org/article/f91d43d20dee49279cc0568179bd731f
Publikováno v:
Environmental Health and Preventive Medicine, Vol 29, Pp 35-35 (2024)
Background: Per- and polyfluoroalkyl substances (PFAS) are global contaminants. Seafood consumption is a possible PFAS exposure route to humans while the isomer specific analysis has not been conducted. Methods: Perfluorooctane sulfonate (PFOS), perf
Externí odkaz:
https://doaj.org/article/14e85f3f50ab42679745ee8414da9483
Autor:
Chisato Terada, Kaho Oh, Ryutaro Tsubaki, Bun Chan, Nozomi Aibara, Kaname Ohyama, Masa-Aki Shibata, Takehiko Wada, Mariko Harada-Shiba, Asako Yamayoshi, Tsuyoshi Yamamoto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/aa9e0af933084a88b819bfb9ce7cf440
Autor:
Tomoaki Kunitsu, Mariko Harada-Shiba, Tomomi Sato, Kazuo Nonomura, Takao Kimura, Kazuya Miyashita, Katsuyuki Nakajima, Masami Murakami
Publikováno v:
Allergology International, Vol 71, Iss 4, Pp 555-557 (2022)
Externí odkaz:
https://doaj.org/article/53ab14629b134e39bca9175907ce08b2
Publikováno v:
Environmental Health and Preventive Medicine, Vol 28, Pp 63-63 (2023)
Background: Zinc absorption and competition among gut bacteria have been reported in animal studies. Thus, gut bacteria may modify zinc availability in humans. Metabolism of intestinal bacteria is known to be necessary for the activation of several p
Externí odkaz:
https://doaj.org/article/b793fef201684eebae54b967457f5d5e
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0295185 (2023)
Lignan polyphenols derived from plants are metabolized by bacteria in the gut to mammalian lignans, such as enterolactone (ENL) and enterodiol (END). Mammalian lignan intake has been reported to be associated with obesity and low blood glucose levels
Externí odkaz:
https://doaj.org/article/c5a58cdba40c472aa114925e4dc8b12c
Autor:
Fumito Wada, Tsuyoshi Yamamoto, Tadayuki Kobayashi, Keisuke Tachibana, Kosuke Ramon Ito, Mayumi Hamasaki, Yukina Kayaba, Chisato Terada, Asako Yamayoshi, Satoshi Obika, Mariko Harada-Shiba
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 957-969 (2021)
Antisense oligonucleotides (ASOs) containing bridged nucleic acids (BNAs) have been proven to be very powerful. However, ensuring a reliable discovery and translational development scheme for this class of ASOs with wider therapeutic windows remains
Externí odkaz:
https://doaj.org/article/abb2609f20634171b35b2ad9423c2d7b
Autor:
Sayaka Funabashi, MD, Yu Kataoka, MD, PhD, Mika Hori, PhD, Masatsune Ogura, MD, PhD, Yuriko Nakaoku, MD, PhD, Kunihiro Nishimura, MD, PhD, Takahito Doi, MD, PhD, Ryo Nishikawa, MD, Kosuke Tsuda, MD, Teruo Noguchi, MD, PhD, Mariko Harada-Shiba, MD, PhD
Publikováno v:
JACC: Asia, Vol 1, Iss 2, Pp 245-255 (2021)
Background: The International Atherosclerosis Society (IAS) has proposed “severe familial hypercholesterolemia” (FH) as a phenotype with the highest cardiovascular risk. However, whether this criteria could appropriately stratify a high-risk Japa
Externí odkaz:
https://doaj.org/article/919678c5992f4a909f394bdd76e7ac22
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Isoflavones found in soy products are a promising class of nutrients that may have a positive effect on human health. In particular, the phytoestrogen metabolite equol is associated with a reduced risk of developing female hormone-related di
Externí odkaz:
https://doaj.org/article/a4863bb84aea4f3d9b6f1ae2227c98d2