Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Marike J. J. G. Stassar"'
Publikováno v:
Journal of Immunological Methods. 330:44-56
Bacterial scFv clones from a naive antibody library have been isolated against cancer cell antigens with AffiSelect, a novel screening method that indirectly identifies candidate library members via an antigen reporter gene. The first step is the coa
Autor:
Hartmut Goldschmidt, Sergey Kipriyanov, Thomas Moehler, Holger J. Schäfer, Marike J. J. G. Stassar, Alexandra Bähre, Björn Cochlovius, Jana Schlenzka, Axel Benner, Melvyn Little, Martin Kornacker
Publikováno v:
Anti-Cancer Drugs. 15:915-919
Combining different treatment strategies offers the possibility of improving treatment results for cancer patients. The aim of our study was therefore to investigate the combination of treatment of established s.c. human B non-Hodgkin's lymphoma in s
Autor:
Simone Seiter, Margot Zöller, Uwe Reinhold, Gunter Rappl, Marike J. J. G. Stassar, Wolfgang Tilgen
Publikováno v:
Journal of Investigative Dermatology. 116(2):344-347
We have previously described the human homolog of a rat metastasis-associated molecule, hC4.4 A, with a weak homology to the urokinase-type plasminogen activator receptor. By the restricted expression in nontransformed tissues as opposed to expressio
Autor:
Björn Cochlovius, Margot Zöller, Marike J. J. G. Stassar, Laura Raddrizzani, J. Hammer, Oliver Christ, Ioannis Mytilineos
Publikováno v:
The Journal of Immunology. 165:4731-4741
The melanoma-associated Ag glycoprotein 100 was analyzed by the T cell epitope prediction software TEPITOPE. Seven HLA-DR promiscuous peptides predicted with a stringent threshold were used to load dendritic cells (DC), and induction of a proliferati
Autor:
Jochen Schuhmacher, Gerhard Moldenhauer, Oliver Christ, Björn Cochlovius, Sergey Kipriyanov, Marike J. J. G. Stassar, Gudrun Strauß, Melvyn Little
Publikováno v:
The Journal of Immunology. 165:888-895
The use of anti-CD3 × antitumor bispecific Abs is an attractive and highly specific approach in cancer therapy. Recombinant Ab technology now provides powerful tools to enhance the potency of such immunotherapeutic constructs. We designed a heterodi
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 125:487-492
The identification of human genes expressed exclusively or preferentially in tumour tissue will be of interest for exploiting the process of oncogenesis, for diagnostic purposes and possibly for developing new strategies in cancer immunotherapy. In a
Publikováno v:
Immunobiology. 203(5)
Recently, epitope prediction software for HLA-DR binding sequences has become available. In view of the importance of T helper (Th) cell activation in immunotherapy of cancer and evidences supporting immunogenicity of renal cell carcinoma (RCC), we h
Autor:
Björn Cochlovius, Marike J. J. G. Stassar, Wolfgang D. Schmitt, Melvyn Little, Wolfgang E. Schmitt
Publikováno v:
Journal of cancer research and clinical oncology. 127(3)
Purpose: To design a tumor-specific immunotherapeutic strategy for treating tumors for which no specific antigens are described (such as bladder urothelial carcinoma), we attempted to activate tumor-specific T-cells by dendritic cells transfected wit