Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marika de Hoop-Sommen"'
Autor:
Joyce E. M. van der Heijden, Marika de Hoop-Sommen, Noa Hoevenaars, Jolien J. M. Freriksen, Koen Joosten, Rick Greupink, Saskia N. de Wildt
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
IntroductionCritically ill patients show large variability in drug disposition due to e.g., age, size, disease and treatment modalities. Physiologically-based pharmacokinetic (PBPK) models can be used to design individualized dosing regimens taking t
Externí odkaz:
https://doaj.org/article/171193c1949d4eec9eea2f643a4373e1
Autor:
Jolien Freriksen, Susan Cole, Joyce van der Heijden, Karen R Yeo, Trevor Johnson, Essam Kerwash, Marika de Hoop-Sommen, Rick Greupink, Janet Nooney, Saskia de Wildt, Ping Zhao
Publikováno v:
Gates Open Research, Vol 7 (2023)
Physiologically based pharmacokinetic (PBPK) models represent computational technology to characterize drug behavior within the context of detailed human physiology. Today, PBPK is routinely used in drug development and regulatory approval to support
Externí odkaz:
https://doaj.org/article/428afdfe2659434fa3aede8712f96746
Autor:
Tjitske M. van der Zanden, Nori J.L. Smeets, Marika de Hoop‐Sommen, Michiel F.T. Schwerzel, Hui Jun Huang, Lieke J.C. Barten, Joyce E.M. van der Heijden, Jolien J.M. Freriksen, Akira A.L. Horstink, Inge H.G. Holsappel, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt
Publikováno v:
Clinical Pharmacology and Therapeutics, 112, 6, pp. 1243-1253
Clinical Pharmacology and Therapeutics, 112, 1243-1253
Clinical Pharmacology and Therapeutics, 112, 1243-1253
Contains fulltext : 287166.pdf (Publisher’s version ) (Open Access) Many drugs are still prescribed off-label to the pediatric population. Although off-label drug use not supported by high level of evidence is potentially harmful, a comprehensive o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e64bd2a84847a574e12004848ed883
http://www.scopus.com/inward/record.url?scp=85138625656&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85138625656&partnerID=8YFLogxK
Autor:
Joyce van der Heijden, Jolien Freriksen, Marika de Hoop-Sommen, Rick Greupink, Saskia de Wildt
Publikováno v:
Archives of Disease in Childhood. 108:A4.3-A5
IntroductionMore than half of all drugs are still prescribed off-label to children. To support off-label dosing, pharmacokinetic (PK) data are needed. Physiologically-based pharmacokinetic (PBPK) models are increasingly used to study PK and guide dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caf4d84f6db1b7257afc94cdf56ad885
https://doi.org/10.1136/archdischild-2023-esdppp.13
https://doi.org/10.1136/archdischild-2023-esdppp.13
Autor:
Tjitske M van der Zanden, Saskia N. de Wildt, Frans G. M. Russel, Laurens F. M. Verscheijden, TN Johnson, Lianne P M van Bussel, Marika de Hoop-Sommen
Publikováno v:
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, 108, 2, pp. 248-252
Clinical Pharmacology and Therapeutics, 108, 248-252
Clinical Pharmacology & Therapeutics
Clinical Pharmacology and Therapeutics, 108(2), 248-252. Wiley-Blackwell
Clinical Pharmacology and Therapeutics, 108, 2, pp. 248-252
Clinical Pharmacology and Therapeutics, 108, 248-252
Clinical Pharmacology & Therapeutics
Clinical Pharmacology and Therapeutics, 108(2), 248-252. Wiley-Blackwell
Contains fulltext : 225414.pdf (Publisher’s version ) (Open Access) As chloroquine (CHQ) is part of the Dutch Centre for Infectious Disease Control coronavirus disease 2019 (COVID-19) experimental treatment guideline, pediatric dosing guidelines ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3368c3982ff87ae8a0cf2801a9fc45
http://europepmc.org/articles/PMC7264731
http://europepmc.org/articles/PMC7264731