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of 3
pro vyhledávání: '"Marika Slivacka"'
Autor:
Ingvar R. Möller, Marika Slivacka, Anne Kathrine Nielsen, Søren G. F. Rasmussen, Ulrik Gether, Claus J. Loland, Kasper D. Rand
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The serotonin transporter (SERT) is responsible for re-uptake of serotonin into the presynaptic neuron and plays a key role in synaptic transmission. Here, the authors use hydrogen-deuterium exchange mass spectrometry to probe the conformational dyna
Externí odkaz:
https://doaj.org/article/0eff74681cb349509bf0274d56961747
Autor:
Søren G. F. Rasmussen, Claus J. Loland, Marika Slivacka, Kasper D. Rand, Ulrik Gether, Anne Kathrine Nielsen, Ingvar R. Möller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Möller, I R, Slivacka, M, Nielsen, A K, Rasmussen, S G F, Gether, U, Loland, C J & Rand, K D 2019, ' Conformational dynamics of the human serotonin transporter during substrate and drug binding ', Nature Communications, vol. 10, no. 1, 1687 . https://doi.org/10.1038/s41467-019-09675-z
Nature Communications
Möller, I R, Slivacka, M, Nielsen, A K, Rasmussen, S G F, Gether, U, Loland, C J & Rand, K D 2019, ' Conformational dynamics of the human serotonin transporter during substrate and drug binding ', Nature Communications, vol. 10, no. 1, 1687 . https://doi.org/10.1038/s41467-019-09675-z
Nature Communications
The serotonin transporter (SERT), a member of the neurotransmitter:sodium symporter family, is responsible for termination of serotonergic signaling by re-uptake of serotonin (5-HT) into the presynaptic neuron. Its key role in synaptic transmission m
Autor:
Kasper D. Rand, Patrick S. Merkle, Ingvar R. Möller, Marika Slivacka, Marek Polák, Růžena Lišková, Alan Kadek, Petr Man, Claus J. Loland, Anne Kathrine Nielsen, Eliska Pospisilova, Jiří Hausner
Publikováno v:
Analytical chemistry. 91(17)
Insight into the structure-function relationship of membrane proteins is important to understand basic cell function and inform drug development, as these are common targets for drugs. Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is an esta