Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marika Fava"'
Autor:
Jaydev Dave, Nour Raad, Nishka Mittal, Lu Zhang, Anthony Fargnoli, Jae Gyun Oh, Maria Elisabetta Savoia, Jens Hansen, Marika Fava, Xiaoke Yin, Konstantinos Theofilatos, Delaine Ceholski, Erik Kohlbrenner, Dongtak Jeong, Lauren Wills, Mathieu Nonnenmacher, Kobra Haghighi, Kevin D Costa, Irene C Turnbull, Manuel Mayr, Chen-Leng Cai, Evangelia G Kranias, Fadi G Akar, Roger J Hajjar, Francesca Stillitano
Publikováno v:
Cardiovasc Res
Aims A mutation in the phospholamban (PLN) gene, leading to deletion of Arg14 (R14del), has been associated with malignant arrhythmias and ventricular dilation. Identifying pre-symptomatic carriers with vulnerable myocardium is crucial because arrhyt
Autor:
Konstantinos Theofilatos, Manuel Mayr, Norman Catibog, Nieves Doménech, B Merkely, Ruifang Lu, María G. Crespo-Leiro, Ferheen Baig, Javier Barallobre-Barreiro, Eric L. Lindberg, Marika Fava, Elisa Duregotti, Bhawana Singh, Ajay M. Shah, Tamás Radovits, Aleksandra Malgorzata Siedlar, Friederike Cuello, Ursula Mayr, Lukas E Schmidt, Diego Martínez-López, Wen-Yu Lin, László Daróczi, Maria Hasman, Norbert Hubner, Elizaveta Ermolaeva
Publikováno v:
RUC. Repositorio da Universidade da Coruña
instname
Circulation
instname
Circulation
Supplemental Digital Content is available in the text.
Background: Remodeling of the extracellular matrix (ECM) is a hallmark of heart failure (HF). Our previous analysis of the secretome of murine cardiac fibroblasts returned ADAMTS5 (a disinte
Background: Remodeling of the extracellular matrix (ECM) is a hallmark of heart failure (HF). Our previous analysis of the secretome of murine cardiac fibroblasts returned ADAMTS5 (a disinte
Autor:
Siqi Yin, Ursula Mayr, Javier Barallobre-Barreiro, Wen Yu Lin, Norman Catibog, Marika Fava, Xiaoke Yin, Lukas Schmidt, Ferheen Baig, Ruifang Lu, Elisa Duregotti, Ella Reed, Anna Barton, Rong Bing, Dyana Markose, Ajay Shah, Konstantinos Theofilatos, Marc Dweck, Neil Henderson, Tamás Radovits, Béla Merkely, Manuel Mayr
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:49
Autor:
Ruifang Lu, Sanjay Sinha, Dieter P. Reinhardt, Shaynah Wanga, Adam Lee Fellows, Marjan Jahangiri, Vivian de Waard, Maarten Groenink, Javier Barallobre-Barreiro, Carlie J.M. de Vries, Barbara J.M. Mulder, Romy Franken, David R. Koolbergen, Rosa Viner, Manuel Mayr, Xiaoke Yin, Qiuru Xing, Aeilko H. Zwinderman, Ron Balm, Ferheen Baig, Philipp Skroblin, Hongorzul Davaapil, Marika Fava
Publikováno v:
Yin, X, Wanga, S, Fellows, A L, Barallobre-Barreiro, J, Lu, R, Davaapil, H, Franken, R, Fava, M, Baig, F, Skroblin, P, Xing, Q, Koolbergen, D R, Groenink, M, Zwinderman, A H, Balm, R, de Vries, C J M, Mulder, B J M, Viner, R, Jahangiri, M, Reinhardt, D P, Sinha, S, de Waard, V & Mayr, M 2019, ' Glycoproteomic Analysis of the Aortic Extracellular Matrix in Marfan Patients. ', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 39, no. 9, pp. 1859–1873 . https://doi.org/10.1161/ATVBAHA.118.312175
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, thrombosis, and vascular biology, 39(9), 1859-1873. Lippincott Williams and Wilkins
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, thrombosis, and vascular biology, 39(9), 1859-1873. Lippincott Williams and Wilkins
Supplemental Digital Content is available in the text.
Objective: Marfan syndrome (MFS) is caused by mutations in FBN1 (fibrillin-1), an extracellular matrix (ECM) component, which is modified post-translationally by glycosylation. This study ai
Objective: Marfan syndrome (MFS) is caused by mutations in FBN1 (fibrillin-1), an extracellular matrix (ECM) component, which is modified post-translationally by glycosylation. This study ai
Autor:
Marjan Jahangiri, Manuel Mayr, Marika Fava, Amalia Forte, Alessandro Della Corte, Marilena Cipollaro, Xiaoke Yin, Ciro Bancone, Marisa De Feo
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 56:458-469
OBJECTIVES We aimed to compare the intracellular proteome of ascending aortas from patients with stenotic bicuspid (BAV) and tricuspid aortic valves (TAV) to identify BAV-specific pathogenetic mechanisms of aortopathy and to verify the previously rep
Autor:
Marika Fava, Athanasios Didangelos, Ferheen Baig, Javier Barallobre-Barreiro, Manuel Mayr, Abhishek Joshi, Marjan Jahangiri, Ruifang Lu, Marc Lynch, Temo Barwari, Norman Catibog, Xiaoke Yin, Ursula Mayr
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Thoracic aortic aneurysm (TAA), a degenerative disease of the aortic wall, is accompanied by changes in the structure and composition of the aortic extracellular matrix (ECM). Evidence is emerging that ECM processing by members of the ADAMTS (a disin
Autor:
Marika Fava, Javier Barallobre-Barreiro, Ursula Mayr, Ruifang Lu, Athanasios Didangelos, Ferheen Baig, Marc Lynch, Norman Catibog, Abhishek Joshi, Temo Barwari, Xiaoke Yin, Marjan Jahangiri, Manuel Mayr
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
King's College London
King's College London
Thoracic aortic aneurysm (TAA), a degenerative disease of the aortic wall, is accompanied by changes in the structure and composition of the aortic ECM (extracellular matrix). The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs
Publikováno v:
Journal of Visualized Experiments : JoVE
Barallobre-Barreiro, J, Baig, F, Fava, M, Yin, X & Mayr, M 2017, ' Glycoproteomics of the extracellular matrix : A method for intact glycopeptide analysis using mass spectrometry ', Journal of Visualized Experiments, vol. 2017, no. 122, e55674 . https://doi.org/10.3791/55674
Barallobre-Barreiro, J, Baig, F, Fava, M, Yin, X & Mayr, M 2017, ' Glycoproteomics of the extracellular matrix : A method for intact glycopeptide analysis using mass spectrometry ', Journal of Visualized Experiments, vol. 2017, no. 122, e55674 . https://doi.org/10.3791/55674
Fibrosis is a hallmark of many cardiovascular diseases and is associated with the exacerbated secretion and deposition of the extracellular matrix (ECM). Using proteomics, we have previously identified more than 150 ECM and ECM-associated proteins in
Autor:
Alkystis Phinikaridou, Matthew Waltham, Xiaoke Yin, Marika Fava, Renata S.M. Gomes, Peter Willeit, Javier Barallobre-Barreiro, Ursula Mayr, René M. Botnar, Alberto Smith, Chris Molenaar, Po-Wah So, Bruce Fanshawe, Manuel Mayr, Abeera Abbas, Marjan Jahangiri, Sarah R. Langley, Rizwan Attia, Ruifang Lu, Anna Zampetaki
Publikováno v:
Circulation Research. 115:857-866
Rationale : Abdominal aortic aneurysms constitute a degenerative process in the aortic wall. Both the miR-29 and miR-15 families have been implicated in regulating the vascular extracellular matrix. Objective : Our aim was to assess the effect of the
Autor:
Marshall Bern, Marika Fava, Marjan Jahangiri, Tessa Werner, Antonios Kourliouros, Mei Chong, Joerg Heineke, Anna Zoccarato, Shashi Kumar Gupta, Ajay M. Shah, Thomas Thum, Anna Zampetaki, Peter Willeit, Marc N. Hirt, Alessandro Viviano, Kinya Otsu, Jens W. Fischer, Manuel Mayr, Rika Kitazume-Taneike, Nieves Doménech, Renato V. Iozzo, Liliana Schaefer, Antoine Kichler, Rosa Viner, Xiaoke Yin, Javier Barallobre-Barreiro
Publikováno v:
Barallobre-Barreiro, J, Gupta, S K, Zoccarato, A, Kitazume-Taneike, R, Fava, M, Yin, X, Werner, T, Hirt, M N, Zampetaki, A, Viviano, A, Chong, M, Bern, M, Kourliouros, A, Domenech, N, Willeit, P, Shah, A M, Jahangiri, M, Schaefer, L, Fischer, J W, Iozzo, R V, Viner, R, Thum, T, Heineke, J, Kichler, A, Otsu, K & Mayr, M 2016, ' Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation ', Circulation (Baltimore), vol. 134, no. 11, pp. 817-832 . https://doi.org/10.1161/CIRCULATIONAHA.115.016423
Background: Myocardial fibrosis is a feature of many cardiac diseases. We used proteomics to profile glycoproteins in the human cardiac extracellular matrix (ECM). Methods: Atrial specimens were analyzed by mass spectrometry after extraction of ECM p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58beab8795530671cec647673eb34ac1
https://openaccess.sgul.ac.uk/id/eprint/109560/1/emss-69498.pdf
https://openaccess.sgul.ac.uk/id/eprint/109560/1/emss-69498.pdf