Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Marijne Vandebergh"'
Autor:
Ide Smets, An Goris, Marijne Vandebergh, Jelle Demeestere, Stefan Sunaert, Patrick Dupont, Bénédicte Dubois
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Magnetization transfer ratio (MTR) and brain volumetric imaging are (semi-)quantitative MRI markers capturing demyelination, axonal degeneration and/or inflammation. However, factors shaping variation in these traits are largely unknown. In
Externí odkaz:
https://doaj.org/article/4866676d871f44caa8029a87fe1be5e5
Autor:
Marijne Vandebergh, Sara Becelaere, CHARGE Inflammation Working Group, Bénédicte Dubois, An Goris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectivesWe explored whether genetically predicted increased body mass index (BMI) modulates multiple sclerosis (MS) risk through interleukin-6 (IL-6) signaling.MethodsWe performed a two-sample Mendelian randomization (MR) study using multiple genom
Externí odkaz:
https://doaj.org/article/8d51cd09c2194f768defda4b10402b8a
Autor:
Vasiliki Lagou, Josselyn E. Garcia-Perez, Ide Smets, Lies Van Horebeek, Marijne Vandebergh, Liye Chen, Klara Mallants, Teresa Prezzemolo, Kelly Hilven, Stephanie Humblet-Baron, Matthieu Moisse, Philip Van Damme, Guy Boeckxstaens, Paul Bowness, Bénédicte Dubois, James Dooley, Adrian Liston, An Goris
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 798-810.e6 (2018)
Summary: The immune system is highly diverse, but characterization of its genetic architecture has lagged behind the vast progress made by genome-wide association studies (GWASs) of emergent diseases. Our GWAS for 54 functionally relevant phenotypes
Externí odkaz:
https://doaj.org/article/35cdeeb0f9534e9380dd0c9868623eb4
Background and ObjectivesDecreased vitamin D levels and obesity are associated with an increased risk for multiple sclerosis (MS). However, whether they also affect the disease course after onset remains unclear. With larger data sets now available,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f778f98a7d497f1c524464b5444608b0
https://lirias.kuleuven.be/handle/20.500.12942/693524
https://lirias.kuleuven.be/handle/20.500.12942/693524
Publikováno v:
Journal of neurology. 269(8)
Multiple sclerosis (MS) is a complex disease with both genetic variants and environmental factors involved in disease susceptibility. The main environmental risk factors associated with MS in observational studies include obesity, vitamin D deficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e92f77a85aa9bef8f0de2fa1b33d32
https://pubmed.ncbi.nlm.nih.gov/35366084
https://pubmed.ncbi.nlm.nih.gov/35366084
Autor:
Till F. M. Andlauer, Bruce V. Taylor, Klara Mallants, Friederike Held, Lilian Aly, An Goris, Bénédicte Dubois, Bernhard Hemmer, Marijne Vandebergh, Yuan Zhou
Publikováno v:
Annals of Neurology
OBJECTIVE: Many multiple sclerosis (MS) genetic susceptibility variants have been identified, but understanding disease heterogeneity remains a key challenge. Relapses are a core feature of MS and a common primary outcome of clinical trials, with pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42441b27fe4bc7ca9a09a9bd15e7f99e
https://pubmed.ncbi.nlm.nih.gov/33704824
https://pubmed.ncbi.nlm.nih.gov/33704824
Autor:
An Goris, Lies Van Horebeek, Emanuela Oldoni, Koen Poesen, Marijne Vandebergh, Bénédicte Dubois, Klara Mallants, Patrick Dupont, Ide Smets
Publikováno v:
Annals of Neurology
OBJECTIVE: Evidence for a role of microglia in the pathogenesis of multiple sclerosis (MS) is growing. We investigated association of microglial markers at time of diagnostic lumbar puncture (LP) with different aspects of disease activity (relapses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e506c9c91a3f5d762f9dc583a16bf7c
https://lirias.kuleuven.be/handle/123456789/651972
https://lirias.kuleuven.be/handle/123456789/651972
Autor:
Vasiliki Lagou, James Dooley, Lien Van Eyck, Carlos P. Roca, Adrian Liston, Erika Van Nieuwenhove, Carine Wouters, Marijne Vandebergh, Ulrich Bodenhofer, An Goris, Stephanie Humblet-Baron
Publikováno v:
Annals of the rheumatic diseases. 78(5)
ObjectivesJuvenile idiopathic arthritis (JIA) is the most common class of childhood rheumatic diseases, with distinct disease subsets that may have diverging pathophysiological origins. Both adaptive and innate immune processes have been proposed as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0b88529d04f560687c19bab048c7e1
https://pubmed.ncbi.nlm.nih.gov/30862608
https://pubmed.ncbi.nlm.nih.gov/30862608
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 24(13)
Background: In contrast to successes for multiple sclerosis (MS) susceptibility, the genetic basis for clinical heterogeneity remains largely unresolved. Objectives: We investigate the first reported genetic association with relapse rate. Methods: We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fb510934cdaa5c43cab2200548e471
https://pubmed.ncbi.nlm.nih.gov/29303040
https://pubmed.ncbi.nlm.nih.gov/29303040
Autor:
Marijne Vandebergh, Adrian Liston, Paul Bowness, An Goris, Stephanie Humblet-Baron, Guy E. Boeckxstaens, Teresa Prezzemolo, James Dooley, Matthieu Moisse, Philip Van Damme, Bénédicte Dubois, Josselyn E. Garcia-Perez, Klara Mallants, Vasiliki Lagou, L Chen, Kelly Hilven, Ide Smets, Lies Van Horebeek
Publikováno v:
Cell Reports
Cell Reports, Vol 25, Iss 3, Pp 798-810.e6 (2018)
Cell Reports, Vol 25, Iss 3, Pp 798-810.e6 (2018)
Summary The immune system is highly diverse, but characterization of its genetic architecture has lagged behind the vast progress made by genome-wide association studies (GWASs) of emergent diseases. Our GWAS for 54 functionally relevant phenotypes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfa204bd1c59f31e6d031b95917d70e