Sex differences in genetic architecture of complex phenotypes?

Autor: Jacqueline M Vink, Meike Bartels, Toos C E M van Beijsterveldt, Jenny van Dongen, Jenny H D A van Beek, Marijn A Distel, Marleen H M de Moor, Dirk J A Smit, Camelia C Minica, Lannie Ligthart, Lot M Geels, Abdel Abdellaoui, Christel M Middeldorp, Jouke Jan Hottenga, Gonneke Willemsen, Eco J C de Geus, Dorret I Boomsma

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e47371 (2012)

We examined sex differences in familial resemblance for a broad range of behavioral, psychiatric and health related phenotypes (122 complex traits) in children and adults. There is a renewed interest in the importance of genotype by sex interaction i

Externí odkaz: https://doaj.org/article/b3e6ab0a60f4479ab989a9b7c09ee13e

Familial resemblance of borderline personality disorder features: genetic or cultural transmission?

Autor: Marijn A Distel, Irene Rebollo-Mesa, Gonneke Willemsen, Catherine A Derom, Timothy J Trull, Nicholas G Martin, Dorret I Boomsma

Publikováno v: PLoS ONE, Vol 4, Iss 4, p e5334 (2009)

Borderline personality disorder is a severe personality disorder for which genetic research has been limited to family studies and classical twin studies. These studies indicate that genetic effects explain 35 to 45% of the variance in borderline per

Externí odkaz: https://doaj.org/article/336e3e867f4b48ec9bd681b74f81c5a7

Borderline personality features in depressed or anxious patients

Autor: Philip Spinhoven, Marijn A. Distel, Johannes H. Smit, Brenda W.J.H. Penninx

Publikováno v: Distel, M A, Smit, J H, Spinhoven, P & Penninx, B W J H 2016, ' Borderline personality features in depressed or anxious patients ', Psychiatry Research, vol. 241, pp. 224-231 . https://doi.org/10.1016/j.psychres.2016.05.007
Psychiatry Research, 241, 224-231. Elsevier Ireland Ltd
Psychiatry Research, 241, 224-231

Anxiety and depression frequently co-occur with borderline personality disorder. Relatively little research examined the presence of borderline personality features and its main domains (affective instability, identity problems, negative relationship

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5220be004d5952e88f709bbb640c1d6
https://research.vumc.nl/en/publications/491e1a36-9c76-4101-b986-3378e2e061de

Borderline personality traits and adult attention-deficit hyperactivity disorder symptoms: a genetic analysis of comorbidity

Autor: Gitta H. Lubke, Christel M. Middeldorp, Angela Carlier, Catherine Derom, Marijn A. Distel, Dorret I. Boomsma

Publikováno v: American journal of medical genetics. Part B, Neuropsychiatric genetics, 156(7), 817-825. Wiley-Liss Inc.
American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 156(7), 817-825. Wiley-Liss Inc.
Distel, M A, Carlier, A, Middeldorp, C M, Derom, C A, Lubke, G H & Boomsma, D I 2011, ' Borderline personality traits and adult attention-deficit hyperactivity disorder symptoms: A genetic analysis of comorbidity ', American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, vol. 156, no. 7, pp. 817-825 . https://doi.org/10.1002/ajmg.b.31226
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 156(7), 817-825. Wiley-Liss Inc.
Distel, M A, Carlier, A, Middeldorp, C M, Derom, C A, Lubke, G H & Boomsma, D I 2011, ' Borderline personality traits and adult attention-deficit hyperactivity disorder symptoms : A genetic analysis of comorbidity ', American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, vol. 156, no. 7, pp. 817-825 . https://doi.org/10.1002/ajmg.b.31226

Previous research has established the comorbidity of adult Attention-Deficit Hyperactivity Disorder (ADHD) with different personality disorders including Borderline Personality Disorder (BPD). The association between adult ADHD and BPD has primarily

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f754243dbf3c40c5ee70597db1085ee0
https://doi.org/10.1002/ajmg.b.31226

Familial Resemblance for Loneliness

Autor: Abdel Abdellaoui, Dorret I. Boomsma, Irene Rebollo-Mesa, John T. Cacioppo, Marijn A. Distel, Catherine Derom, Gonneke Willemsen

Publikováno v: Distel, M A, Rebollo Mesa, I, Abdellaoui, A, Derom, C A, Willemsen, G, Cacioppo, J T & Boomsma, D I 2010, ' Familial Resemblance for Loneliness ', Behavior Genetics, vol. 40, no. 4, pp. 480-494 . https://doi.org/10.1007/s10519-010-9341-5
Behavior Genetics, 40(4), 480-494. Springer
Behavior Genetics

Social isolation and loneliness in humans have been associated with physical and psychological morbidity, as well as mortality. This study aimed to assess the etiology of individual differences in feelings of loneliness. The genetic architecture of l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1090fc4e7295898e1658e48e7d6d4045
https://doi.org/10.1007/s10519-010-9341-5