Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marijke W A Molenaar-de Backer"'
Autor:
Anne Russcher, Michiel van Boven, Elisa Benincà, E. J. T. (Joanne) Verweij, Marijke W. A. Molenaar-de Backer, Hans L. Zaaijer, Ann C. T. M. Vossen, Aloys C. M. Kroes
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Parvovirus B19V (B19V) infection during pregnancy can be complicated by potentially life-threatening fetal hydrops, which can be managed by intrauterine transfusion (IUT). This study investigates the long-term temporal patterns in the epidem
Externí odkaz:
https://doaj.org/article/a54246fd285f44f2acfea8e1b4debaf9
Autor:
Marijke W A Molenaar-de Backer, Vladimir V Lukashov, Rob S van Binnendijk, Hein J Boot, Hans L Zaaijer
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43206 (2012)
Parvovirus B19 (B19V) can cause infection in humans. To date, three genotypes of B19V, with subtypes, are known, of which genotype 1a is the most prevalent genotype in the Western world. We sequenced the genome of B19V strains of 65 asymptomatic, rec
Externí odkaz:
https://doaj.org/article/a3939d6b3049467ea33a3ffff5b20280
Autor:
Marijke W. A. Molenaar-de Backer, Paulien Doodeman, Fereshte Rezai, Lisa M. Verhagen, Arno van der Ark, Els M. Plagmeijer, Bernard Metz, Naomi van Vlies, Olga Ophorst, René H. M. Raeven
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Intrinsic or added immune activating molecules are key for most vaccines to provide desired immunity profiles but may increase systemic reactogenicity. Regulatory agencies require rabbit pyrogen testing (RPT) for demonstration of vaccine rea
Externí odkaz:
https://doaj.org/article/e4e7d7d3c4fe4e64adcffc572b4ed1ec
Autor:
Ruth, Daniels, Wim, Van der Elst, Nele, Dieltjens, Tinne, Appels, Chi K, So, Thomas, Nys, Liesbeth, Voeten, Philip, Breugelmans, Marijke W A, Molenaar-de Backer, Eelo, Gitz, Stephen, Poole, Mehul, Patel
Publikováno v:
ALTEX.
Pharmaceutical products intended for parenteral use must be free from pyrogenic (fever-inducing) contamination. Pyrogens comprise endotoxins from Gram-negative bacteria and non-endotoxin pyrogens from Gram-positive bacteria, viruses, and fungi. The l
Performance of monocyte activation test supplemented with human serum compared to fetal bovine serum
Publikováno v:
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 38(2), 307-315. Elsevier GmbH
The monocyte activation test (MAT) is used to detect pyrogens in pharmaceutical products and serves as replacement of the rabbit pyrogen test. The peripheral blood mononuclear cell-based MAT assay requires the addition of serum to the medium and is p
Publikováno v:
Transfusion. 56(2)
To meet European guidelines for plasma for fractionation, plasma fractionators have implemented parvovirus B19 (B19V) and hepatitis A virus (HAV) nucleic acid test (NAT) screening on test pools. In this study we evaluate recently developed in-house N