Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marijke Schrock"'
Suppressor mutations in Mecp2-null mice implicate the DNA damage response in Rett syndrome pathology
Autor:
Julie Ruston, Jay Shendure, Christie M. Buchovecky, Elif Acar, Marijke Schrock, Adebola Enikanolaiye, Christine Taylor, Monica J. Justice, Rong Zeng
Publikováno v:
Genome Res
Mutations in X-linked methyl-CpG-binding protein 2 (MECP2) cause Rett syndrome (RTT). To identify functional pathways that could inform therapeutic entry points, we carried out a genetic screen for secondary mutations that improved phenotypes in Mecp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f77973c66cfc17bc8b7b1b98551f69
https://europepmc.org/articles/PMC7197480/
https://europepmc.org/articles/PMC7197480/
Autor:
Jay Shendure, A. Enikanolaiye, C. Taylor, R. Zeng, J. Ruston, Christie M. Buchovecky, E. Acar, Monica J. Justice, Marijke Schrock
Mutations in X-linked methyl-CpG-binding protein 2 (MECP2) cause Rett syndrome (RTT). We carried out a genetic screen for secondary mutations that improved phenotypes in Mecp2/Y mice after mutagenesis with N-ethyl-N-nitrosourea (ENU), aiming to ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2e94dcd497cca88718726d5dcbebaf
https://doi.org/10.1101/810929
https://doi.org/10.1101/810929
Autor:
Peter Bialek, Xiangli Yang, Gerard Karsenty, Marijke Schrock, Eric N. Olson, Monica J. Justice, Nancy A. Hong, Kai Yu, Hua Wu, Drazen Sosic, Britt Kern, David M. Ornitz
Publikováno v:
Developmental Cell. 6(3):423-435
Runx2 is necessary and sufficient for osteoblast differentiation, yet its expression precedes the appearance of osteoblasts by 4 days. Here we show that Twist proteins transiently inhibit Runx2 function during skeletogenesis. Twist-1 and -2 are expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d2a5f5d20257577099b6b8e1f12e25c
