Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marijke Hyke Algera"'
Autor:
Marieke Hellinga, Marijke Hyke Algera, Rutger van der Schrier, Elise Sarton, Monique van Velzen, Albert Dahan, Erik Olofsen, Marieke Niesters
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106520- (2023)
Summary: Opioids are commonly used painkillers and drugs of abuse and have serious toxic effects including potentially lethal respiratory depression. It remains unknown which respiratory parameter is the most sensitive biomarker of opioid-induced res
Externí odkaz:
https://doaj.org/article/63648f48afb7473eb08b1c02f75d6390
Autor:
Erik Olofsen, Marijke Hyke Algera, Laurence Moss, Robert L. Dobbins, Geert J. Groeneveld, Monique van Velzen, Marieke Niesters, Albert Dahan, Celine M. Laffont
Publikováno v:
JCI Insight, Vol 7, Iss 9 (2022)
BACKGROUND Potent synthetic opioids, such as fentanyl, are increasingly abused, resulting in unprecedented numbers of fatalities from respiratory depression. Treatment with the high-affinity mu-opioid receptor partial agonist buprenorphine may preven
Externí odkaz:
https://doaj.org/article/faf5c86fc2f348318525716d62bbc243
Autor:
Laurence M Moss, Marijke Hyke Algera, Robert Dobbins, Frank Gray, Stephanie Strafford, Amy Heath, Monique van Velzen, Jules A A C Heuberger, Marieke Niesters, Erik Olofsen, Celine M Laffont, Albert Dahan, Geert Jan Groeneveld
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0256752 (2022)
BackgroundOpioid-induced respiratory depression driven by ligand binding to mu-opioid receptors is a leading cause of opioid-related fatalities. Buprenorphine, a partial agonist, binds with high affinity to mu-opioid receptors but displays partial re
Externí odkaz:
https://doaj.org/article/eb0051078bd44d70bf246c8aab572e7d
Autor:
Marieke Hellinga, Marijke Hyke Algera, Erik Olofsen, Rutger van der Schrier, Elise Sarton, Monique van Velzen, Albert Dahan, Marieke Niesters
Publikováno v:
Clinical Pharmacology & Therapeutics. 113:1080-1088
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::172f6b54447fa75b1b965f10c5c4e56b
https://doi.org/10.1002/cpt.2863
https://doi.org/10.1002/cpt.2863
Autor:
Erik Olofsen, Marijke Hyke Algera, Laurence Moss, Robert L. Dobbins, Geert J. Groeneveld, Monique van Velzen, Marieke Niesters, Albert Dahan, Celine M. Laffont
Publikováno v:
JCI Insight, 7(9). AMER SOC CLINICAL INVESTIGATION INC
BACKGROUND. Potent synthetic opioids, such as fentanyl, are increasingly abused, resulting in unprecedented numbers of fatalities from respiratory depression. Treatment with the high-affinity mu-opioid receptor partial agonist buprenorphine may preve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90762cbd5394b2b14892fc6308c7043
https://pubmed.ncbi.nlm.nih.gov/35316224
https://pubmed.ncbi.nlm.nih.gov/35316224
Autor:
Laurence M. Moss, Marijke Hyke Algera, Robert Dobbins, Frank Gray, Stephanie Strafford, Amy Heath, Monique van Velzen, Jules A. A. C. Heuberger, Marieke Niesters, Erik Olofsen, Celine M. Laffont, Albert Dahan, Geert Jan Groeneveld
Publikováno v:
PLoS ONE
PLoS ONE, Vol 17, Iss 1, p e0256752 (2022)
PLoS ONE, 17(1). PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 17, Iss 1, p e0256752 (2022)
PLoS ONE, 17(1). PUBLIC LIBRARY SCIENCE
BackgroundOpioid-induced respiratory depression driven by ligand binding to mu-opioid receptors is a leading cause of opioid-related fatalities. Buprenorphine, a partial agonist, binds with high affinity to mu-opioid receptors but displays partial re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59152a471541f9419327a38651de7055
https://pubmed.ncbi.nlm.nih.gov/35085249
https://pubmed.ncbi.nlm.nih.gov/35085249
Autor:
Laurence M Moss, Jules A. A. C. Heuberger, Robert L. Dobbins, Marieke Niesters, Celine M. Laffont, Erik Olofsen, Marijke Hyke Algera, Albert Dahan, Monique van Velzen, Geert Jan Groeneveld
Publikováno v:
Clinical Pharmacology and Therapeutics
Clinical Pharmacology & Therapeutics, 109(3), 637-645. WILEY
Clinical Pharmacology & Therapeutics, 109(3), 637-645. WILEY
Chronic opioid consumption is associated with addiction, physical dependence, and tolerance. Tolerance results in dose escalation to maintain the desired opioid effect. Intake of high-dose or potent opioids may cause life-threatening respiratory depr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45daf3ef8be6da98261915a671efea18
https://pubmed.ncbi.nlm.nih.gov/32865832
https://pubmed.ncbi.nlm.nih.gov/32865832
Autor:
Marijke Hyke Algera, Elise Sarton, Marieke Niesters, Terry Smith, Albert Dahan, Monique van Velzen, Cornelis Jan van Dam, Leon Aarts, Erik Olofsen
Publikováno v:
Annals of Palliative Medicine, 9(2), 528-536. AME PUBL CO
Opioids are complex drugs that produce profit (most importantly analgesia) as well as a myriad of adverse effects including gastrointestinal motility disturbances, abuse and addiction, sedation and potentially lethal respiratory depression (RD). Cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481bf3d860aa530aba64b99ffd97768c
https://doi.org/10.21037/apm.2019.10.09
https://doi.org/10.21037/apm.2019.10.09
Autor:
Marijke Hyke Algera, Leon Aarts, Marieke Niesters, Albert Dahan, Jasper Kamp, Rutger van der Schrier, Monique van Velzen, Erik Olofsen
Publikováno v:
British Journal of Anaesthesia, 122(6), E168-E179
Background Opioids are potent painkillers but come with serious adverse effects ranging from addiction to potentially lethal respiratory depression. A variety of drugs with separate mechanisms of action are available to prevent or reverse opioid-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beee61f92de68fce26ac2b30f04477a1
http://hdl.handle.net/1887/120882
http://hdl.handle.net/1887/120882