Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Marije Slingerland"'
Autor:
Estelle Tran Van Hoi, Saskia J. Santegoets, Simon P. Mooijaart, Diana Van Heemst, Asli Özkan, Elizabeth M. E. Verdegaal, Marije Slingerland, Ellen Kapiteijn, Sjoerd H. van der Burg, Johanneke E. A. Portielje, Marij J. P. Welters, Nienke A. de Glas
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Introduction Immunotherapy with checkpoint inhibition (ICI) is increasingly prescribed to older patients with cancer. High age, especially in combination with frailty, has been associated to immune senescence, which is the age-related declin
Externí odkaz:
https://doaj.org/article/6b9b79aef64e4aa1babf70adc5e34c33
Autor:
Charlotte I. Stroes, Sybren L. Meijer, Geert-Jan Creemers, Gerrit K.J. Hooijer, Nadia Haj Mohammad, Maartje Los, Marije Slingerland, Geke A.P. Hospers, Annemieke Cats, Laurens V. Beerepoot, Maarten F. Bijlsma, Hanneke W.M. van Laarhoven
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102079- (2024)
Background: HER2 targeting in esophageal adenocarcinoma (EAC) has shown potential, but often fails to show durable response. Given the contributions of the tumor immune microenvironment (TIME) to therapeutic responses, we aimed to chart the TIME char
Externí odkaz:
https://doaj.org/article/140bcec5bc5649c49d43672c34967d9a
Autor:
Hans Gelderblom, Marta Fiocco, Simon P Mooijaart, Gerrit-Jan Liefers, Wilbert B van den Hout, Frank M Speetjens, Frederiek van den Bos, Leti van Bodegom-Vos, Marije Slingerland, Nienke A de Glas, Johanneke E A Portielje, Marissa Cloos-van Balen, Joosje C Baltussen, Trishika R R Binda, Arjan J Verschoor, Cynthia Holterhues, Danny Houtsma, Anouk Jochems, Leontine E A M M Spierings
Publikováno v:
BMJ Open, Vol 14, Iss 8 (2024)
Introduction Treating older adults with chemotherapy remains a challenge, given their under-representation in clinical trials and the lack of robust treatment guidelines for this population. Moreover, older patients, especially those with frailty, ha
Externí odkaz:
https://doaj.org/article/cc10accdfbcd4ad6ba94b0ed10167cff
Autor:
Alessio Ciurli, Yassene Mohammed, Christine Ammon, Rico J.E. Derks, Damien Olivier-Jimenez, Quinten R. Ducarmon, Marije Slingerland, Jacques Neefjes, Martin Giera
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108884- (2024)
Summary: Saliva is a complex bodily fluid composed of secretions by major and minor salivary glands. Salivary glands and their secretions are known to be unevenly distributed in the human oral cavity. Moreover, saliva flow rate and composition vary a
Externí odkaz:
https://doaj.org/article/b3a4b4b6f4ca4069981542cafed3309b
Autor:
Sarah K. Hakuno, Stefanus G. T. Janson, Marjolijn D. Trietsch, Manon de Graaf, Eveline de Jonge-Muller, Stijn Crobach, Tom J. Harryvan, Jurjen J. Boonstra, Winand N. M. Dinjens, Marije Slingerland, Lukas J. A. C. Hawinkels
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Despite the fact that the role of endoglin on endothelial cells has been extensively described, its expression and biological role on (epithelial) cancer cells is still debatable. Especially its function on squamous cell carcinoma (SCC) cells is larg
Externí odkaz:
https://doaj.org/article/05416853dd5b46b9bc43f9f08ab20a32
Autor:
Anouk W. M. A. Schaeffers, Lot A. Devriese, Carla H. van Gils, Jan Willem Dankbaar, Jens Voortman, Jan Paul de Boer, Marije Slingerland, Mathijs P. Hendriks, Ernst J. Smid, Geert W. J. Frederix, Remco de Bree
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/384294a837e14ac9ba26c18410221c79
Autor:
Hans Gelderblom, Sjoerd H van der Burg, Ferry Ossendorp, Peggy J de Vos van Steenwijk, Mariette I E van Poelgeest, Inge Roozen, Willem-Jan Krebber, Cornelis J M Melief, Frank M Speetjens, Marij J P Welters, Nikki M Loof, Sanne Boekestijn, Catharina A H Janssen, Marije Slingerland, Gijs G Zom, A Rob P M Valentijn, Nico J Meeuwenoord, Gijs A van der Marel, Dmitri V Filippov
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Background Amplivant is a molecularly optimized Toll-like receptor 2 ligand that can be covalently conjugated to tumor peptide antigens. In preclinical models, amplivant-adjuvanted synthetic long peptides (SLPs) strongly enhanced antigen presentation
Externí odkaz:
https://doaj.org/article/116d0102ba984134b3b45409c8b1b84b
Autor:
Yara van Holstein, Floor J. van Deudekom, Stella Trompet, Iris Postmus, Anna Uit den Boogaard, Marjan J. T. van der Elst, Nienke A. de Glas, Diana van Heemst, Geert Labots, Mariëtte Altena, Marije Slingerland, Gerrit Jan Liefers, Frederiek van den Bos, Jessica M. van der Bol, Gerard J. Blauw, Johanneke E. A. Portielje, Simon P. Mooijaart
Publikováno v:
BMC Geriatrics, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Treatment decisions concerning older patients can be very challenging and individualised treatment plans are often required in this very heterogeneous group. In 2015 we have implemented a routine clinical care pathway for older pa
Externí odkaz:
https://doaj.org/article/d7e8737fcbe746618b3d69ceafdddef0
Autor:
Charlotte I Stroes, Sandor Schokker, Mohammed Khurshed, Stephanie O van der Woude, Ron AA Mathôt, Marije Slingerland, Judith de Vos-Geelen, Massimo Zucchetti, Cristina Matteo, Erik van Dijk, Bauke Ylstra, Victor Thijssen, Sarah Derks, Tesfay Godefa, Willemieke Dijksterhuis, Gerben E Breimer, Otto M van Delden, Rob HA Verhoeven, Sybren L Meijer, Maarten F Bijlsma, Hanneke WM van Laarhoven
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Purpose: Regorafenib monotherapy, a multikinase inhibitor of angiogenesis, tumor microenvironment, and tumorigenesis, showed promising results in gastric cancer. We aimed to assess the tolerability of regorafenib and paclitaxel in patients with advan
Externí odkaz:
https://doaj.org/article/aed72a810b8b46b7a7487a5ebbe32545
Autor:
Marieke Pape, Pauline A. J. Vissers, David Bertwistle, Laura McDonald, Marije Slingerland, Nadia Haj Mohammad, Laurens V. Beerepoot, Jelle P. Ruurda, Grard A. P. Nieuwenhuijzen, Paul M. Jeene, Hanneke W. M. van Laarhoven, Rob H. A. Verhoeven
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Real-world data on treatment and outcomes in patients with synchronous metastatic disease compared with patients with metachronous metastatic disease in esophagogastric cancer have not been published before. The aim of our study was to ex
Externí odkaz:
https://doaj.org/article/2c976c490a0d44018ae1ad2163774b56