Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Marije I, Koenders"'
CD64 as novel molecular imaging marker for the characterization of synovitis in rheumatoid arthritis
Autor:
Wessel F. Theeuwes, Irene Di Ceglie, Daphne N. Dorst, Arjen B. Blom, Desiree L. Bos, Thomas Vogl, Sander W. Tas, Pilar Jimenez-Royo, Mats Bergstrom, Matthew Cleveland, Peter M. van der Kraan, Peter Laverman, Marije I. Koenders, Peter L. van Lent, Martijn H. J. van den Bosch
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-15 (2023)
Abstract Background Rheumatoid arthritis (RA) is one of the most prevalent and debilitating joint diseases worldwide. RA is characterized by synovial inflammation (synovitis), which is linked to the development of joint destruction. Magnetic resonanc
Externí odkaz:
https://doaj.org/article/2aad6123f8ac4ee5adcf05a7f4fb72f2
Autor:
Onno J. Arntz, Rogier M. Thurlings, Esmeralda N. Blaney Davidson, Pascal W. T. C. Jansen, Michiel Vermeulen, Marije I. Koenders, Peter M. van der Kraan, Fons A. J. van de Loo
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
BackgroundRheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovial inflammation and cartilage/bone damage. Intercellular messengers such as IL-1 and TNF play a crucial role in the pathophysiology of RA but have limited dia
Externí odkaz:
https://doaj.org/article/0fdda973c7cd427699c6d95bfaeef970
Autor:
Natália Valdrighi, Arjen B. Blom, Henk M. van Beuningen, Elly L. Vitters, Monique M. Helsen, Birgitte Walgreen, Peter L.E.M. van Lent, Marije I. Koenders, Peter M. van der Kraan, Fons A.J. van de Loo, Esmeralda N. Blaney Davidson
Publikováno v:
PeerJ, Vol 11, p e15482 (2023)
Background Osteoarthritis (OA) is a progressive joint disease and a major cause of chronic pain in adults. The prevalence of OA is higher in female patients, who tend to have worse OA outcomes, partially due to pain. The association between joint pai
Externí odkaz:
https://doaj.org/article/03fdaf6af3ba4d28bb9268a02e580afc
Autor:
Joyce Aarts, Arjan van Caam, Xinlai Chen, Renoud J. Marijnissen, Monique M. Helsen, Birgitte Walgreen, Elly L. Vitters, Fons A. van de Loo, Peter L. van Lent, Peter M. van der Kraan, Marije I. Koenders
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract TGF-β1 is an important growth factor to promote the differentiation of T helper 17 (Th17) and regulatory T cells (Treg). The potential of TGF-β1 as therapeutic target in T cell-mediated diseases like rheumatoid arthritis (RA) is unclear. W
Externí odkaz:
https://doaj.org/article/e56341f6fbb745499f284ebee7d9f397
Autor:
Bianka Marklein, Madeleine Jenning, Zoltán Konthur, Thomas Häupl, Franziska Welzel, Ute Nonhoff, Sylvia Krobitsch, Debbie M. Mulder, Marije I. Koenders, Vijay Joshua, Andrew P. Cope, Mark J. Shlomchik, Hans-Joachim Anders, Gerd R. Burmester, Aase Hensvold, Anca I. Catrina, Johan Rönnelid, Günter Steiner, Karl Skriner
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-16 (2021)
Abstract Background There is a need for biomarker to identify patients “at risk” for rheumatoid arthritis (risk-RA) and to better predict the therapeutic response and in this study we tested the hypothesis that novel native and citrullinated hete
Externí odkaz:
https://doaj.org/article/6e28ab54dbcf4c858aedc3ba90e27fcf
Autor:
Irene Di Ceglie, Peter L. E. M. van Lent, Edwin J. W. Geven, Marije I. Koenders, Arjen B. Blom, Thomas Vogl, Johannes Roth, Martijn H. J. van den Bosch
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Excessive osteoclast activity, which is strongly stimulated by pro-inflammatory mediators, results in bone and cartilage degeneration as central features of many arthritides. Levels of the alarmin S100A8/A9 and interleukin (IL)-1
Externí odkaz:
https://doaj.org/article/007fde91b5b342df9e647aa4c1e5e630
Autor:
Natália Valdrighi, Arjen B. Blom, Juliana P. Vago, Henk M. van Beuningen, Elly L. Vitters, Monique M. Helsen, Birgitte Walgreen, Onno J. Arntz, Marije I. Koenders, Peter M. van der Kraan, Esmeralda N. Blaney Davidson, Fons A. J. van de Loo
Publikováno v:
Cells, Vol 12, Iss 14, p 1913 (2023)
Joint pain severity in arthritic diseases differs between sexes and is often more pronounced in women. This disparity is thought to stem from biological mechanisms, particularly innate immunity, yet the understanding of sex-specific differences in ar
Externí odkaz:
https://doaj.org/article/c4935f31599a45a9bccf4b49b14a63a7
Autor:
Juliana P. Vago, Natália Valdrighi, Esmeralda N. Blaney-Davidson, Daniel L. A. H. Hornikx, Margot Neefjes, María E. Barba-Sarasua, Nathalie G. M. Thielen, Martijn H. J. van den Bosch, Peter M. van der Kraan, Marije I. Koenders, Flávio A. Amaral, Fons A. J. van de Loo
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 703 (2023)
Osteoarthritis (OA) is the most prevalent joint disease, and it is characterized by cartilage degeneration, synovitis, and bone sclerosis, resulting in swelling, stiffness, and joint pain. TAM receptors (Tyro3, Axl, and Mer) play an important role in
Externí odkaz:
https://doaj.org/article/047bc96dcbe34cb9b01ef0b135fe48be
Autor:
Joyce Aarts, Annemarie Boleij, Bartijn C. H. Pieters, Anouk L. Feitsma, R. J. Joost van Neerven, Jean Paul ten Klooster, Laura M’Rabet, Onno J. Arntz, Marije I. Koenders, Fons A. J. van de Loo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Many studies provided compelling evidence that extracellular vesicles (EVs) are involved in the regulation of the immune response, acting as both enhancers and dampeners of the immune system, depending on the source and type of vesicle. Research, inc
Externí odkaz:
https://doaj.org/article/7206aa4f590f40579215db13f8663deb
Autor:
Bianka Marklein, Madeleine Jenning, Zoltán Konthur, Thomas Häupl, Franziska Welzel, Ute Nonhoff, Sylvia Krobitsch, Debbie M. Mulder, Marije I. Koenders, Vijay Joshua, Andrew P. Cope, Mark J. Shlomchik, Hans-Joachim Anders, Gerd R. Burmester, Aase Hensvold, Anca I. Catrina, Johan Rönnelid, Günter Steiner, Karl Skriner
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/c6a3f6ea4dc34591a50ebdb7f3693e1d