Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Marija Vujcic"'
Autor:
Eriko Katsuta, Kazuaki Takabe, Marija Vujcic, Philip A. Gottlieb, Tao Dai, Arnaldo Mercado-Perez, Arthur Beyder, Qingfei Wang, Mateusz Opyrchal
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9909 (2022)
Background: Mechanically gated PIEZO channels lead to an influx of cations, activation of additional Ca2+ channels, and cell depolarization. This study aimed to investigate PIEZO2’s role in breast cancer. Methods: The clinical relevance of PIEZO2 e
Externí odkaz:
https://doaj.org/article/feb3eaebe3f94456952378ab47d0d4c6
Autor:
Martin Weinberger, Li Feng, Anita Paul, Daniel L Smith, Robert D Hontz, Jeffrey S Smith, Marija Vujcic, Keshav K Singh, Joel A Huberman, William C Burhans
Publikováno v:
PLoS ONE, Vol 2, Iss 8, p e748 (2007)
The chronological lifespan of eukaryotic organisms is extended by the mutational inactivation of conserved growth-signaling pathways that regulate progression into and through the cell cycle. Here we show that in the budding yeast S. cerevisiae, thes
Externí odkaz:
https://doaj.org/article/c8043480319e44ffa96975d02288a377
We have used yeast Saccharomyces cerevisiae as a tool to identify the importance of mitochondrial processes involved in arsenic-induced carcinogenicity in humans. We screened 466 single-gene knockout strains of yeast S. cerevisiae known to be involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d28ebc33d08e006e945a64435fcd38f
https://doi.org/10.1158/0008-5472.c.6496779
https://doi.org/10.1158/0008-5472.c.6496779
Supplementary Data from Genetic Determinants of Mitochondrial Response to Arsenic in Yeast Saccharomyces cerevisiae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c312697cab8ee805b4976aaaab06f4
https://doi.org/10.1158/0008-5472.22371396.v1
https://doi.org/10.1158/0008-5472.22371396.v1
Supplementary Tables 1-7 from Genetic Determinants of Mitochondrial Response to Arsenic in Yeast Saccharomyces cerevisiae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3c864a8646fcfb094ab2f9c739d8f7
https://doi.org/10.1158/0008-5472.22371393
https://doi.org/10.1158/0008-5472.22371393
To identify novel genes that mediate cellular resistance to cisplatin, we have screened the collection of Saccharomyces cerevisiae deletion strains. We have found reproducibly 22 genes/open reading frames (ORF), which when deleted, confer resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e3c5e2036041b58a771f7143eb69a2
https://doi.org/10.1158/0008-5472.c.6493733
https://doi.org/10.1158/0008-5472.c.6493733
Supplementary Table 1 from Genome-Wide Screen Identifies Genes Whose Inactivation Confer Resistance to Cisplatin in Saccharomyces cerevisiae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518c13d9c95351b77b55469f4ab4e2b1
https://doi.org/10.1158/0008-5472.22363487.v1
https://doi.org/10.1158/0008-5472.22363487.v1
Publikováno v:
Cancer Research. 80:P6-07
Introduction: Breast cancer is the most common female malignancy. Despite improvements in therapeutic options, metastatic disease remains incurable with limited treatments especially in triple-negative breast cancer (TNBC). Clinical outcomes in patie
Autor:
Miao Qu, David Hangauer, Marija Vujcic, Chengjian Tu, Jun Li, Jun Qu, James L. Clements, Shichen Shen, Yahao Bu
Publikováno v:
Journal of proteome research. 15(9)
Despite a demonstrated role for TNF-α in promoting muscle wasting and cachexia, the associated molecular mechanisms and signaling pathways of myoblast differentiation dysregulated by TNF-α remain poorly understood. This study presents well-controll
Publikováno v:
Journal of human genetics
Decreased mitochondrial oxidative phosphorylation (OXPHOS) is one of the hallmarks of cancer. To date, the identity of nuclear gene(s) responsible for decreased OXPHOS in tumors remains unknown. It is also unclear whether mutations in nuclear gene(s)