Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Marija Cvijovic"'
Autor:
Svenja Braam, Farida Tripodi, Linnea Österberg, Sebastian Persson, Niek Welkenhuysen, Paola Coccetti, Marija Cvijovic
Publikováno v:
Microbial Cell, Vol 11, Pp 143-154 (2024)
The AMPK/SNF1 pathway governs energy balance in eukaryotic cells, notably influencing glucose de-repression. In S. cerevisiae, Snf1 is phosphorylated and hence activated upon glucose depletion. This activation is required but is not sufficient for me
Externí odkaz:
https://doaj.org/article/941c4325e28d4c31b7c751286f155105
Autor:
Marija Cvijovic, Annikka Polster
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Complex diseases are prevalent medical conditions which are characterized by inter-patient heterogeneity with regards to symptom profiles, disease trajectory, comorbidities, and treatment response. Their pathophysiology involves a combination of gene
Externí odkaz:
https://doaj.org/article/57adfc30743d42ac835cb55e9691facf
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 7, p e1010261 (2022)
The accumulation of protein damage is one of the major drivers of replicative ageing, describing a cell's reduced ability to reproduce over time even under optimal conditions. Reactive oxygen and nitrogen species are precursors of protein damage and
Externí odkaz:
https://doaj.org/article/ac896dae26b941778267f2797e03254c
Autor:
Annikka Polster, Lena Öhman, Julien Tap, Muriel Derrien, Boris Le Nevé, Johanna Sundin, Hans Törnblom, Marija Cvijovic, Magnus Simrén
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Although incompletely understood, microbiota-host interactions are assumed to be altered in irritable bowel syndrome (IBS). We, therefore, aimed to develop a novel analysis pipeline tailored for the integrative analysis of microbiota-host in
Externí odkaz:
https://doaj.org/article/06b022d47b4b4e6d98e7d0e4754ed30b
Publikováno v:
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract The GTPase Cdc42 is the master regulator of eukaryotic cell polarisation. During this process, the active form of Cdc42 is accumulated at a particular site on the cell membrane called the pole. It is believed that the accumulation of the act
Externí odkaz:
https://doaj.org/article/c4525d41d50d4bb2a14d381be141d7d3
Autor:
Sebastian Persson, Niek Welkenhuysen, Sviatlana Shashkova, Samuel Wiqvist, Patrick Reith, Gregor W Schmidt, Umberto Picchini, Marija Cvijovic
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 5, p e1010082 (2022)
Understanding the inherited nature of how biological processes dynamically change over time and exhibit intra- and inter-individual variability, due to the different responses to environmental stimuli and when interacting with other processes, has be
Externí odkaz:
https://doaj.org/article/e8bf43694da246f39ac5665c98f9b16b
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 4, p e1008891 (2021)
The interplay between nutrient-induced signaling and metabolism plays an important role in maintaining homeostasis and its malfunction has been implicated in many different human diseases such as obesity, type 2 diabetes, cancer, and neurological dis
Externí odkaz:
https://doaj.org/article/5f5425c6b1434c4d81ee883f5d9026a1
Autor:
Patrick Reith, Svenja Braam, Niek Welkenhuysen, Sarah Lecinski, Jack Shepherd, Chris MacDonald, Mark C. Leake, Stefan Hohmann, Sviatlana Shashkova, Marija Cvijovic
Publikováno v:
Microorganisms, Vol 10, Iss 3, p 590 (2022)
Lithium salts are used in the treatment of mood disorders, cancer, and Alzheimer’s disease. It has been shown to prolong life span in several phyla; however, not yet in budding yeast. In our study, we investigate the influence of lithium on yeast c
Externí odkaz:
https://doaj.org/article/6310dbe7c49e4a6db65b6e2d26c339a2
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1008314 (2020)
Damaged proteins are inherited asymmetrically during cell division in the yeast Saccharomyces cerevisiae, such that most damage is retained within the mother cell. The consequence is an ageing mother and a rejuvenated daughter cell with full replicat
Externí odkaz:
https://doaj.org/article/5350ba4abaaa45f388906420746cd393
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Nutrient sensing pathways are playing an important role in cellular response to different energy levels. In budding yeast, Saccharomyces cerevisiae, the sucrose non-fermenting protein kinase complex SNF1 is a master regulator of energy homeostasis. I
Externí odkaz:
https://doaj.org/article/85b2a66691164c1e9e550004dc9a7021