Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Marija A Djurkovic"'
Autor:
Ariel Shepley-McTaggart, Jingjing Liang, Yang Ding, Marija A Djurkovic, Valeriia Kriachun, Olena Shtanko, Oriol Sunyer, Ronald N Harty
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011595 (2023)
Ebola (EBOV) and Marburg viruses (MARV) cause severe hemorrhagic fever associated with high mortality rates in humans. A better understanding of filovirus-host interactions that regulate the EBOV and MARV lifecycles can provide biological and mechani
Externí odkaz:
https://doaj.org/article/fbe473186be64d29a4b95c1fd33611c7
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 120(2)
The filovirus VP40 protein directs virion egress, which is regulated either positively or negatively by select VP40–host interactions. We demonstrate that host BAG3 and HSP70 recognize VP40 as a client and inhibit the egress of VP40 virus-like part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cf8e49bbcc8f0a05610a3e361bf243
https://pubmed.ncbi.nlm.nih.gov/36598950
https://pubmed.ncbi.nlm.nih.gov/36598950
Publikováno v:
Autophagy. :1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fd74283c9cd60488e56154fa3d0a39d
https://doi.org/10.1080/15548627.2023.2178781
https://doi.org/10.1080/15548627.2023.2178781
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Filovirus-host interactions play important roles in all stages of the virus lifecycle. Here, we identify LATS1/2 kinases and YAP, key components of the Hippo pathway, as critical regulators of EBOV transcription and egress. Specifically, we
Externí odkaz:
https://doaj.org/article/23875c06d84b41d29612e95e37cfb856