Prevalence of human filovirus infections in sub-Saharan Africa: A systematic review and meta-analysis protocol

Autor: Christopher S. Semancik, Christopher L. Cooper, Thomas S. Postler, Matt Price, Heejin Yun, Marija Zaric, Monica Kuteesa, Nina Malkevich, Andrew Kilianski, Swati B. Gupta, Suzanna C. Francis

Publikováno v: Systematic Reviews, Vol 13, Iss 1, Pp 1-9 (2024)

Abstract Background Recent outbreaks of Ebola virus disease (EVD) and Marburg virus disease (MVD) in sub-Saharan Africa illustrate the need to better understand animal reservoirs, burden of disease, and human transmission of filoviruses. This protoco

Externí odkaz: https://doaj.org/article/99ebfd36f0aa4a6595a3a59b778dc196

Poor CD4+ T Cell Immunogenicity Limits Humoral Immunity to P. falciparum Transmission-Blocking Candidate Pfs25 in Humans

Autor: Marija Zaric, Arianna Marini, Carolyn M. Nielsen, Gaurav Gupta, David Mekhaiel, Thao P. Pham, Sean C. Elias, Iona J. Taylor, Hans de Graaf, Ruth O. Payne, Yuanyuan Li, Sarah E. Silk, Chris Williams, Adrian V. S. Hill, Carole A. Long, Kazutoyo Miura, Sumi Biswas

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Plasmodium falciparum transmission-blocking vaccines (TBVs) targeting the Pfs25 antigen have shown promise in mice but the same efficacy has never been achieved in humans. We have previously published pre-clinical data related to a TBV candidate Pfs2

Externí odkaz: https://doaj.org/article/f21e9455de774a698a42b7af607f559b

Skin immunisation activates an innate lymphoid cell-monocyte axis regulating CD8+ effector recruitment to mucosal tissues

Autor: Marija Zaric, Pablo D. Becker, Catherine Hervouet, Petya Kalcheva, Andor Doszpoly, Negin Blattman, Lauren A. O’ Neill, Barbara Ibarzo Yus, Clement Cocita, Sung-Yun Kwon, Andrew H. Baker, Graham M. Lord, Linda S. Klavinskis

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

Mucosal immunisation is important for initiating mucosal CD8+ T­cell responses but mucosal recruitment of protective CD8+ T cells can also be induced by skin immunisation. Here the authors examine the underlying mechanism and report a novel role for

Externí odkaz: https://doaj.org/article/50310e1b618c4e9db13be9368bb83233

Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly

Autor: Geneviève M. Labbé, Eerik Aunin, Yrene Themistocleous, Jee Sun Cho, Raquel Lopez Ramon, Julian C. Rayner, Baktash Khozoee, Chayanut Suansomjit, Sarah E. Silk, Doris Quinkert, Alison Kemp, Thomas D. Otto, Iona J. Taylor, Alison M. Lawrie, Simon J. Draper, Angela M. Minassian, Thomas A. Rawlinson, Marija Zaric, Celia Mitton, Jason C. Sousa, Jetsumon Sattabongkot, Andrew M. Blagborough, Sumi Biswas, Kimberly J. Johnson, Florian Bach, Chalermpon Kumpitak, Adam J. Reid, Margaux Mulatier, Nongnuj Maneechai, Ian D. Poulton, Katherine J. Ellis, Nattawan Rachaphaew, Nick J. Edwards, Fernando Ramos Lopez, Philip J Spence, Carolyn M. Nielsen, Wanlapa Roobsoong, Arianna Marini, Kirsty McHugh, Megan Baker, David J. Roberts, Mimi M. Hou, Tianrat Piteekan, Jordan R. Barrett, Fay L. Nugent

Publikováno v: Minassian, A M, Themistocleous, Y, Silk, S E, Barrett, J R, Kemp, A, Quinkert, D, Nielsen, C M, Edwards, N J, Rawlinson, T A, Ramos Lopez, F, Roobsoong, W, Ellis, K J D, Cho, J-S, Aunin, E, Otto, T D, Reid, A J, Bach, F A, Labbé, G M C, Poulton, I D, Marini, A, Zaric, M, Mulatier, M, Lopez Ramon, R, Baker, M, Mitton, C H, Sousa, J C, Rachaphaew, N, Kumpitak, C, Maneechai, N, Suansomjit, C, Piteekan, T, Hou, M M, Khozoee, B, McHugh, K, Roberts, D J, Lawrie, A M, Blagborough, A M, Nugent, F L, Taylor, I J, Johnson, K J, Spence, P J, Sattabongkot, J, Biswas, S, Rayner, J C & Draper, S J 2021, ' Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly ', JCI Insight, vol. 6, no. 23, e152465 . https://doi.org/10.1172/jci.insight.152465
JCI Insight

Controlled human malaria infection (CHMI) provides a highly informative means to investigate host-pathogen interactions and enable in vivo proof-of-concept efficacy testing of new drugs and vaccines. However, unlike Plasmodium falciparum, well-charac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc190240819a778fd98762e57e377c28
https://doi.org/10.1172/jci.insight.152465

Controlled human malaria infection with PvW1 – a new clone of Plasmodium vivax with high quality genome assembly

Autor: Raquel Lopez Ramon, Chayanut Suansomjit, Fernando Ramos Lopez, Angela M. Minassian, Philip J Spence, Margaux Mulatier, Baktash Khozoee, Florian Bach, Carolyn M. Nielsen, Katherine J. Ellis, Chalermpon Kumpitak, Megan Baker, Jordan R. Barrett, Nattawan Rachaphaew, Sarah E. Silk, Kimberly J. Johnson, Ian D. Poulton, Doris Quinkert, Nick J. Edwards, Mimi M. Hou, Alison M. Lawrie, Yrene Themistocleous, Tianrat Piteekan, Simon J. Draper, Jee Sun Cho, Wanlapa Roobsoong, Adam J. Reid, Arianna Marini, Nongnuj Maneechai, Geneviève M. Labbé, Jetsumon Sattabongkot, Celia Mitton, Iona J. Taylor, Julian C. Rayner, Fay L. Nugent, Jason C. Sousa, Thomas D. Otto, David J. Roberts, Alison Kemp, Andrew M. Blagborough, Thomas A. Rawlinson, Marija Zaric, Sumi Biswas, Eerik Aunin

Controlled human malaria infection (CHMI) provides a highly informative means to investigate host-pathogen interactions and enable in vivo proof-of-concept efficacy testing of new drugs and vaccines. However, unlike Plasmodium falciparum, well-charac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62f64e0fc59168d7bbe0cbbdc65a18c6
https://doi.org/10.1101/2021.07.23.21259839