Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Marij J. P. Welters"'
Autor:
Markus Haake, Beatrice Haack, Tina Schäfer, Patrick N. Harter, Greta Mattavelli, Patrick Eiring, Neha Vashist, Florian Wedekink, Sabrina Genssler, Birgitt Fischer, Julia Dahlhoff, Fatemeh Mokhtari, Anastasia Kuzkina, Marij J. P. Welters, Tamara M. Benz, Lena Sorger, Vincent Thiemann, Giovanni Almanzar, Martina Selle, Klara Thein, Jacob Späth, Maria Cecilia Gonzalez, Carmen Reitinger, Andrea Ipsen-Escobedo, Kilian Wistuba-Hamprecht, Kristin Eichler, Katharina Filipski, Pia S. Zeiner, Rudi Beschorner, Renske Goedemans, Falk Hagen Gogolla, Hubert Hackl, Rogier W. Rooswinkel, Alexander Thiem, Paula Romer Roche, Hemant Joshi, Dirk Pühringer, Achim Wöckel, Joachim E. Diessner, Manfred Rüdiger, Eugen Leo, Phil F. Cheng, Mitchell P. Levesque, Matthias Goebeler, Markus Sauer, Falk Nimmerjahn, Christine Schuberth-Wagner, Stefanie von Felten, Michel Mittelbronn, Matthias Mehling, Andreas Beilhack, Sjoerd H. van der Burg, Angela Riedel, Benjamin Weide, Reinhard Dummer, Jörg Wischhusen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Immune checkpoint blockade therapy is beneficial and even curative for some cancer patients. However, the majority don’t respond to immune therapy. Across different tumor types, pre-existing T cell infiltrates predict response to checkpoin
Externí odkaz:
https://doaj.org/article/5207814fce1e426b9e431dafa4d554e4
Autor:
Anna Paaso, Hanna‐Mari Koskimaa, Marij J. P. Welters, Katja Kero, Jaana Rautava, Kari Syrjänen, Sjoerd H. van derBurg, Stina Syrjänen
Publikováno v:
Clinical and Experimental Dental Research, Vol 7, Iss 5, Pp 903-913 (2021)
Abstract Objectives Natural history of human papillomavirus (HPV) infection in the head and neck region is poorly understood, and their impact on collective HPV‐specific immunity is not known. Materials and methods In this study, we have performed
Externí odkaz:
https://doaj.org/article/86be8d6c39684baeb268e0c2cd24f932
Autor:
Stefanie de Groot, Rieneke T. Lugtenberg, Danielle Cohen, Marij J. P. Welters, Ilina Ehsan, Maaike P. G. Vreeswijk, Vincent T. H. B. M. Smit, Hiltje de Graaf, Joan B. Heijns, Johanneke E. A. Portielje, Agnes J. van de Wouw, Alex L. T. Imholz, Lonneke W. Kessels, Suzan Vrijaldenhoven, Arnold Baars, Elma Meershoek-Klein Kranenbarg, Marjolijn Duijm-de Carpentier, Hein Putter, Jacobus J. M. van der Hoeven, Johan W. R. Nortier, Valter D. Longo, Hanno Pijl, Judith R. Kroep, Dutch Breast Cancer Research Group (BOOG)
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Preclinical evidence suggests that a fasting mimicking diet (FMD) can make cancer cells more vulnerable to chemotherapy, while protecting normal cells. In this randomized phase II clinical trial of 131 patients with HER2 negative early stage breast c
Externí odkaz:
https://doaj.org/article/ece7e746301b495eb80ac3a814697099
Autor:
Tone Otterhaug, Sylvia Janetzki, Marij J. P. Welters, Monika Håkerud, Anne Grete Nedberg, Victoria Tudor Edwards, Sanne Boekestijn, Nikki M. Loof, Pål Kristian Selbo, Hans Olivecrona, Sjoerd H. van der Burg, Anders Høgset
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Background and AimsPhotochemical internalization (PCI) is a technology for inducing release of endocytosed antigens into the cell cytosol via a light-induced process. Preclinical experiments have shown that PCI improves MHC class I antigen presentati
Externí odkaz:
https://doaj.org/article/fab00cabe1f240a9a5504b442e7a5871
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Oropharyngeal squamous cell carcinoma (OPSCC) develops as a consequence of several mutations in the tumor suppressor pathways or after a progressive infection with high risk human papillomavirus (HPV). The dismal side effects of the current standard
Externí odkaz:
https://doaj.org/article/420565c3fe0940fbad78f20c9ed85952
Autor:
Ziena Abdulrahman, Noel de Miranda, Edith M G van Esch, Peggy J de Vos van Steenwijk, Marij J. P. Welters, Mariette I E van Poelgeest
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
BackgroundVulvar high-grade squamous intraepithelial lesion (vHSIL) is predominantly induced by high-risk human papilloma virus type 16 (HPV16). In two independent trials, therapeutic vaccination against the HPV16 E6 and E7 oncoproteins resulted in o
Externí odkaz:
https://doaj.org/article/0e0d2f0ef1a04f048f971b6ef0646463
Autor:
Joosje C. Baltussen, Marij J. P. Welters, Elizabeth M. E. Verdegaal, Ellen Kapiteijn, Anne M. R. Schrader, Marije Slingerland, Gerrit-Jan Liefers, Sjoerd H. van der Burg, Johanneke E. A. Portielje, Nienke A. de Glas
Publikováno v:
Cancers, Vol 13, Iss 24, p 6366 (2021)
Immune checkpoint inhibitors (ICIs) have strongly improved the survival of melanoma patients. However, as durable response to ICIs are only seen in a minority, there is an unmet need to identify biomarkers that predict response. Therefore, we provide
Externí odkaz:
https://doaj.org/article/ff698bd3cb814541850b59eba59d596e
Autor:
Anouk Corbeau, Remi A. Nout, Jan Willem M. Mens, Nanda Horeweg, Jérémy Godart, Ellen M. Kerkhof, Sander C. Kuipers, Mariette I. E. van Poelgeest, Judith R. Kroep, Ingrid A. Boere, Helena C. van Doorn, Mischa S. Hoogeman, Uulke A. van der Heide, Hein Putter, Marij J. P. Welters, Sjoerd H. van der Burg, Carien L. Creutzberg, Stephanie M. de Boer
Publikováno v:
Cancers, Vol 13, Iss 20, p 5179 (2021)
External beam radiation therapy (EBRT) with concurrent chemotherapy followed by brachytherapy is a very effective treatment for locally advanced cervical cancer (LACC). However, treatment-related toxicity is common and reduces the patient’s quality
Externí odkaz:
https://doaj.org/article/d341305a04fe4fd289b98eefee29523e
Autor:
Diane van der Woude, Theo Rispens, Catharina M Korse, Sjoerd H van der Burg, Ellen Kapiteijn, John B A G Haanen, Winan J van Houdt, Els M E Verdegaal, Marij J P Welters, Jessica S W Borgers, Tineke J van Wesemael, Johannes V van Thienen, Kyra A Gelderman, Dirk J A R Moes
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)
Introduction Treatment with the immune checkpoint inhibitor anti-programmed cell death protein-1 (PD-1) often causes immune-related adverse events (irAEs). Since irAEs resemble autoimmune diseases, autoantibodies might play a role and could potential
Externí odkaz:
https://doaj.org/article/9616b7f6fe8b499baab93acfee17c709
Publikováno v:
Vaccines, Vol 4, Iss 3, p 29 (2016)
Immunotherapy shows promising clinical results in patients with different types of cancer, but its full potential is not reached due to immune dysfunction as a result of several suppressive mechanisms that play a role in cancer development and progre
Externí odkaz:
https://doaj.org/article/e980c732a2414e278e30af693611c2de