Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mariia R. Mollaeva"'
Autor:
Maria B. Sokol, Veronika A. Beganovskaya, Mariia R. Mollaeva, Nikita G. Yabbarov, Margarita V. Chirkina, Dmitry V. Belykh, Olga M. Startseva, Anton E. Egorov, Alexey A. Kostyukov, Vladimir A. Kuzmin, Sergei M. Lomakin, Natalia G. Shilkina, Alexey V. Krivandin, Olga V. Shatalova, Margarita A. Gradova, Maxim A. Abakumov, Aleksey A. Nikitin, Varvara P. Maksimova, Kirill I. Kirsanov, Elena D. Nikolskaya
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 126 (2024)
In this study, we described physico-chemical properties of novel nanoformulation of photosensitizer-pyropheophorbide α 17-diethylene glycol ester (XL) (chlorophyll α derivative), revealing insights into antitumor activity and maintaining quality, m
Externí odkaz:
https://doaj.org/article/63e96922ff644c18a4b19ed5782c51bf
Autor:
Maria B. Sokol, Vera A. Sokhraneva, Nataliya V. Groza, Mariia R. Mollaeva, Nikita G. Yabbarov, Margarita V. Chirkina, Anna A. Trufanova, Vladimir I. Popenko, Elena D. Nikolskaya
Publikováno v:
Polymers, Vol 16, Iss 1, p 72 (2023)
Unsaturated fatty acids, such as oleic acid (OA) and linoleic acid (LA), are promising antimicrobial and cytostatic agents. We modified OA and LA with thymol (TOA and TLA, respectively) to expand their bioavailability, stability, and possible applica
Externí odkaz:
https://doaj.org/article/f2f41a7024914ca58877577b1469dd10
Autor:
Yulia S. Bortnevskaya, Nikita A. Shiryaev, Nikita S. Zakharov, Oleg O. Kitoroage, Margarita A. Gradova, Natalia Yu. Karpechenko, Alexander S. Novikov, Elena D. Nikolskaya, Mariia R. Mollaeva, Nikita G. Yabbarov, Natal’ya A. Bragina, Kseniya A. Zhdanova
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1284 (2023)
Photodynamic therapy (PDT) in oncology is characterized by low invasiveness, minimal side effects, and little tissue scarring. Increasing the selectivity of PDT agents toward a cellular target is a new approach intended to improve this method. This s
Externí odkaz:
https://doaj.org/article/c0abe2ac11014b9693c151d1af8025bc
Autor:
Polina M. Tyubaeva, Ivetta A. Varyan, Elena D. Nikolskaya, Mariia R. Mollaeva, Nikita G. Yabbarov, Maria B. Sokol, Margarita V. Chirkina, Anatoly A. Popov
Publikováno v:
Nanomaterials, Vol 13, Iss 2, p 236 (2023)
The effect of the hemin (Hmi) on the structure and properties of nanocomposite electrospun materials based on poly-3-hydroxybutyrate (PHB) is discussed in the article. The additive significantly affected the morphology of fibers allowed to produce mo
Externí odkaz:
https://doaj.org/article/5b8ef7b066d94066bf54f480fb9388d9
Autor:
Margarita A. Gradova, Oleg V. Gradov, Anton V. Lobanov, Anna V. Bychkova, Elena D. Nikolskaya, Nikita G. Yabbarov, Mariia R. Mollaeva, Anton E. Egorov, Alexey A. Kostyukov, Vladimir A. Kuzmin, Irina S. Khudyaeva, Dmitry V. Belykh
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 345 (2022)
A novel amphiphilic cationic chlorin e6 derivative was investigated as a promising photosensitizer for photodynamic therapy. Two cationic –N(CH3)3+ groups on the periphery of the macrocycle provide additional hydrophilization of the molecule and en
Externí odkaz:
https://doaj.org/article/b3f5861d02e348ce96e6007f831b0e34
Autor:
Maria B. Sokol, Margarita V. Chirkina, Nikita G. Yabbarov, Mariia R. Mollaeva, Tatyana A. Podrugina, Anna S. Pavlova, Viktor V. Temnov, Rania M. Hathout, Abdelkader A. Metwally, Elena D. Nikolskaya
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2333 (2022)
Currently, molecular dynamics simulation is being widely applied to predict drug–polymer interaction, and to optimize drug delivery systems. Our study describes a combination of in silico and in vitro approaches aimed at improvement in polymer-base
Externí odkaz:
https://doaj.org/article/bf9a0587d234408699b4ff6024953dd5
Autor:
Konstantin V. Palamarchuk, Tatiana N. Borodina, Anastasia V. Kostenko, Yury M. Chesnokov, Roman A. Kamyshinsky, Natalya P. Palamarchuk, Elena B. Yudina, Elena D. Nikolskaya, Nikita G. Yabbarov, Mariia R. Mollaeva, Tatiana V. Bukreeva
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 575 (2022)
Capsules with shells based on nanoparticles of different nature co-assembled at the interface of liquid phases of emulsion are promising carriers of lipophilic drugs. To obtain such capsules, theoretically using the Derjaguin–Landau–Verwey–Over
Externí odkaz:
https://doaj.org/article/edd1747dd0504530bc82bab803640c47
Autor:
Mariia R. Mollaeva, Elena Nikolskaya, Veronika Beganovskaya, Maria Sokol, Margarita Chirkina, Sergey Obydennyi, Dmitry Belykh, Olga Startseva, Murad D. Mollaev, Nikita Yabbarov
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1985 (2021)
Pheophorbide a 17-diethylene glycol ester (XL-8), is a promising high-active derivative of known photosensitizer chlorin e6 used in photodynamic therapy. However, high lipophilicity and poor tumor accumulation limit XL-8 therapeutic application. We d
Externí odkaz:
https://doaj.org/article/db12fc8a605a4b1190bbc5b8b6edb199
Autor:
Mariia R. Mollaeva, Nikita Yabbarov, Maria Sokol, Margarita Chirkina, Murad D. Mollaev, Artur Zabolotskii, Irina Seregina, Mikhail Bolshov, Alexander Kaplun, Elena Nikolskaya
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12261 (2021)
The selection of technological parameters for nanoparticle formulation represents a complicated development phase. Therefore, the statistical analysis based on Box–Behnken methodology is widely used to optimize technological processes, including po
Externí odkaz:
https://doaj.org/article/d4217c143c614d45b2cf599665d50cba
Autor:
Mariya B Sokol, Nikita G Yabbarov, Mariia R Mollaeva, Margarita V Chirkina, Murad D Mollaev, Artur I Zabolotsky, Sergey L Kuznetsov, Elena D Nikolskaya
Publikováno v:
Nanomedicine. 17:1217-1235
Background: Serious side effects caused by paclitaxel formulation, containing toxic solubilizer Cremophor® EL, and its nonspecific accumulation greatly limit clinical paclitaxel application. Aim: To design paclitaxel-loaded copolymer of lactic and g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b014a69793fde7842c2973693f474e5
https://doi.org/10.2217/nnm-2022-0097
https://doi.org/10.2217/nnm-2022-0097