Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Marietta Y W T, Lee"'
Publikováno v:
Animal Models and Experimental Medicine, Vol 5, Iss 5, Pp 461-469 (2022)
Abstract Background Replication stress response is crucial for the maintenance of a stable genome. POLDIP3 (DNA polymerase delta interacting protein 3) was initially identified as one of the DNA polymerase δ (Pol δ) interacting proteins almost 20 y
Externí odkaz:
https://doaj.org/article/6d19d7e2110445ca98accb83a5d04a96
Publikováno v:
Animal Models and Experimental Medicine. 5:461-469
Replication stress response is crucial for the maintenance of a stable genome. POLDIP3 (DNA polymerase delta interacting protein 3) was initially identified as one of the DNA polymerase δ (Pol δ) interacting proteins almost 20 years ago. Using a va
Autor:
Manrose Singh, Sufang Zhang, Alexis M. Perez, Ernest Y. C. Lee, Marietta Y. W. T. Lee, Dong Zhang
Publikováno v:
Genes. 13(11)
POLDIP3 was initially identified as a DNA polymerase delta (Pol δ) interacting protein almost twenty years ago. Intriguingly, it also interacts with proteins involved in a variety of RNA related biological processes, such as transcription, pre-mRNA
Publikováno v:
Genes. 14:893
Mutations of numerous genes involved in DNA replication, DNA repair, and DNA damage response (DDR) pathways lead to a variety of human diseases, including aging and cancer [...]
The replication stress response is crucial for the maintenance of a stable genome. POLDIP3 was initially identified as one of the DNA polymerase δ (Pol δ) interacting proteins almost twenty years ago. Using a variety of in vitro biochemical assays,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2612c01c8f5741fa43762e161d818c38
https://doi.org/10.21203/rs.3.rs-1564802/v1
https://doi.org/10.21203/rs.3.rs-1564802/v1
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39156 (2012)
Mammalian DNA polymerase δ (Pol δ), a four-subunit enzyme, plays a crucial and versatile role in DNA replication and DNA repair processes. We have reconstituted human Pol δ complexes in insect cells infected with a single baculovirus into which on
Externí odkaz:
https://doaj.org/article/f85d815369d3423187ca8030a435a9b6
Autor:
Yujue Wang, Qian Zhang, Huiqing Chen, Xiao Li, Weijun Mai, Keping Chen, Sufang Zhang, Ernest Y C Lee, Marietta Y W T Lee, Yajing Zhou
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27092 (2011)
Mammalian DNA polymerase δ (pol δ), a four-subunit enzyme, plays a crucial and versatile role in DNA replication and various DNA repair processes. Its function as a chromosomal DNA polymerase is dependent on the association with proliferating cell
Externí odkaz:
https://doaj.org/article/ae2234a9f8a3421ba80d4b5f31efda4a
Autor:
Yajing Zhou, Huiqing Chen, Xiao Li, Yujue Wang, Keping Chen, Sufang Zhang, Xiao Meng, Ernest Y C Lee, Marietta Y W T Lee
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22224 (2011)
Eukaryotic DNA polymerase δ (pol δ) plays a crucial role in chromosomal DNA replication and various DNA repair processes. It is thought to consist of p125, p66 (p68), p50 and p12 subunits. However, rigorous isolation of mammalian pol δ from natura
Externí odkaz:
https://doaj.org/article/7a6c1bafd58b4c409f5d6e1ddb35e563
Publikováno v:
The Journal of biological chemistry. 282(21)
Mammalian DNA polymerase (Pol) delta is essential for DNA replication. It consists of four subunits, p125, p50, p68, and p12. We report the discovery that the p12 subunit is rapidly degraded in cultured human cells by DNA damage or replication stress
Publikováno v:
Cell cycle (Georgetown, Tex.). 4(2)
Replication Factor C (RFC) is required for the loading of Proliferating Cell Nuclear Antigen (PCNA) onto DNA during DNA replication, repair and recombination. RFC40, the second subunit of the RFC complex, and PCNA have been shown to be overexpressed