Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Marietta L Harrison"'
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 4, p e1003546 (2014)
Computational approaches to tune the activation of intracellular signal transduction pathways both predictably and selectively will enable researchers to explore and interrogate cell biology with unprecedented precision. Techniques to control complex
Externí odkaz:
https://doaj.org/article/ad9bf01d162e485fb5f266261066d568
Autor:
Hui Cai, Elena G Chiorean, Michael V Chiorean, Douglas K Rex, Bruce W Robb, Noah M Hahn, Ziyue Liu, Patrick J Loehrer, Marietta L Harrison, Yan Xu
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57081 (2013)
Only in recent years have phospholipase A2 enzymes (PLA2s) emerged as cancer targets. In this work, we report the first detection of elevated PLA2 activities in plasma from patients with colorectal, lung, pancreatic, and bladder cancers as compared t
Externí odkaz:
https://doaj.org/article/c628a348113c433b9bdfd1c4f18d630e
Autor:
Benjamin C. Jennings, Marissa J. Nadolski, Yiping Ling, Meredith Beckham Baker, Marietta L. Harrison, Robert J. Deschenes, Maurine E. Linder
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 2, Pp 233-242 (2009)
Pharmacologic approaches to studying palmitoylation are limited by the lack of specific inhibitors. Recently, screens have revealed five chemical classes of small molecules that inhibit cellular processes associated with palmitoylation (Ducker, C. E.
Externí odkaz:
https://doaj.org/article/b8b013495c83440087a18c2fb78c4dbe
Publikováno v:
Peptides and Protein Phosphorylation ISBN: 9781351075442
Peptides and Protein Phosphorylation
Peptides and Protein Phosphorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66e39f156f42f274af17dc5138ed0910
https://doi.org/10.1201/9781351075442-10
https://doi.org/10.1201/9781351075442-10
Autor:
Patrick J. Loehrer, Min Zhang, Marietta L. Harrison, Elena G. Chiorean, Siwei Wei, Daniel Raftery, Lingli Deng, Joseph F. Pekny, Haiwei Gu, G. A. Nagana Gowda, Dabao Zhang, Chen Chen, Mohammad Abu Zaid
Publikováno v:
Journal of Proteome Research. 14:2492-2499
Despite the fact that colorectal cancer (CRC) is one of the most prevalent and deadly cancers in the world, the development of improved and robust biomarkers to enable screening, surveillance, and therapy monitoring of CRC continues to be evasive. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691465e91bbff7182528e4d1c8175205
https://doi.org/10.1021/acs.jproteome.5b00059
https://doi.org/10.1021/acs.jproteome.5b00059
Autor:
Min Zhang, Marietta L. Harrison, Mohammad Abu Zaid, Daniel Raftery, G. A. Nagana Gowda, Lingli Deng, E. Gabriela Chiorean, Chen Chen, Haiwei Gu, Jiangjiang Zhu, Dabao Zhang
Publikováno v:
Metabolomics. 13
INTRODUCTION: Metabolomics technologies enable the identification of putative biomarkers for numerous diseases; however, the influence of confounding factors on metabolite levels poses a major challenge in moving forward with such metabolites for pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f864f7b24030bc124410c6b2c1a56bd5
https://doi.org/10.1007/s11306-017-1265-0
https://doi.org/10.1007/s11306-017-1265-0
Autor:
Marietta L. Harrison, Judith Mikolajczak, Jeffrey P. Perley, Ann E. Rundell, Gregery T. Buzzard
Publikováno v:
Processes, Vol 2, Iss 4, Pp 867-900 (2014)
Processes
Volume 2
Issue 4
Pages 867-900
Processes
Volume 2
Issue 4
Pages 867-900
Signal intensity and feedback regulation are known to be major factors in the signaling events stemming from the T-cell receptor (TCR) and its various coreceptors, but the exact nature of these relationships remains in question. We present a mathemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1adf93300e099515af881f862f6c1e
http://www.mdpi.com/2227-9717/2/4/867
http://www.mdpi.com/2227-9717/2/4/867
Autor:
Liza Shrestha, Jiao Song, Kalub Hahne, James L. Donelson, Jaimeen D. Majmudar, Marietta L. Harrison, Christine A. Hrycyna, Heather B. Hodges-Loaiza, Richard A. Gibbs
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:283-295
Human protein isoprenylcysteine carboxyl methyltransferase (hIcmt) is the enzyme responsible for the α-carboxyl methylation of the C-termimal isoprenylated cysteine of CaaX proteins, including Ras proteins. This specific posttranslational methylatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e1ec8c6f4f7ccafb8a2d605b6344a9
https://doi.org/10.1016/j.bmc.2011.10.087
https://doi.org/10.1016/j.bmc.2011.10.087
Autor:
W. Andy Tao, Marietta L. Harrison, Jianjie Hu, Jacob A. Galan, Su Sien Ong, Victoria A. Martin, Robert L. Geahlen, Haiyan Ma, Leela L. Paris
Publikováno v:
Journal of Biological Chemistry. 285:39844-39854
The Syk protein-tyrosine kinase is phosphorylated on multiple tyrosines after the aggregation of the B cell antigen receptor. However, metabolic labeling experiments indicate that Syk is inducibly phosphorylated to an even greater extent on serine af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf068332feee9cc6f2c81b694c8cc78
https://doi.org/10.1074/jbc.m110.164509
https://doi.org/10.1074/jbc.m110.164509
Autor:
Marissa J. Nadolski, Meredith Beckham Baker, Robert J. Deschenes, Maurine E. Linder, Benjamin C. Jennings, Marietta L. Harrison, Yiping Ling
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 2, Pp 233-242 (2009)
Pharmacologic approaches to studying palmitoylation are limited by the lack of specific inhibitors. Recently, screens have revealed five chemical classes of small molecules that inhibit cellular processes associated with palmitoylation (Ducker, C. E.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e46f77d20b2bb91c8e06932d677dcc6
https://doi.org/10.1194/jlr.m800270-jlr200
https://doi.org/10.1194/jlr.m800270-jlr200