Výsledky vyhledávání - "Marietta Iltcheva"

Akademický článek

Modulation by Ethanol of Cigarette Smoke Clastogenicity in Cells of Adult Mice and of Transplacentally Exposed Fetuses.

Autor: Roumen Balansky, Sebastiano La Maestra, Rosanna T Micale, Marietta Iltcheva, Krassimir Kirov, Silvio De Flora

Publikováno v: PLoS ONE, Vol 11, Iss 12, p e0167239 (2016)

Cigarette smoke (CS) and ethanol (EtOH) are known to synergize in the causation of cancers of the upper aerodigestive tract and of the liver. Little is known about possible interactions between these agents in other organs. These premises prompted us

Externí odkaz: https://doaj.org/article/ea1adf95a8294024b499dd3d441d4ea8

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Early and late effects of aspirin and naproxen on microRNAs in the lung and blood of mice, either unexposed or exposed to cigarette smoke

Autor: Mariagrazia Longobardi, Anna Camoirano, Alberto Izzotti, Sebastiano La Maestra, Francesco D'Agostini, Mark Steven Miller, Marta Geretto, Alessandra Pulliero, Silvio De Flora, Roumen Balansky, Rosanna T. Micale, Marietta Iltcheva, Vernon E. Steele, Gancho Ganchev

Publikováno v: Oncotarget

// Alberto Izzotti 1, 2 , Roumen Balansky 3 , Gancho Ganchev 3 , Marietta Iltcheva 3 , Mariagrazia Longobardi 1 , Alessandra Pulliero 1 , Anna Camoirano 1 , Francesco D'Agostini 1 , Marta Geretto 1 , Rosanna T. Micale 1 , Sebastiano La Maestra 1 , Ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d20877251286d83781448a0b09003b5
https://doi.org/10.18632/oncotarget.20464

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Interactions between ethanol and cigarette smoke in a mouse lung carcinogenesis model

Autor: Rosanna T. Micale, Roumen Balansky, Manasi Nikolov, Silvio De Flora, Marietta Iltcheva, S La Maestra, Gancho Ganchev, Vernon E. Steele

Publikováno v: Toxicology. 373:54-62

Both ethanol and cigarette smoke are classified as human carcinogens. They can synergize, especially in tissues of the upper aerodigestive tract that are targeted by both agents. The main objective of the present study was to evaluate the individual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261ab31523417316000e299ae7b9569f
https://doi.org/10.1016/j.tox.2016.11.008

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Pharmacological Modulation of Lung Carcinogenesis in Smokers: Preclinical and Clinical Evidence

Autor: Rosanna T. Micale, Roumen Balansky, Gancho Ganchev, Marietta Iltcheva, Vernon E. Steele, Silvio De Flora, Sebastiano La Maestra

Publikováno v: Trends in Pharmacological Sciences. 37:120-142

Many drugs in common use possess pleiotropic properties that make them capable of interfering with carcinogenesis mechanisms. We discuss here the ability of pharmacological agents to mitigate the pulmonary carcinogenicity of mainstream cigarette smok

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7eadb6b983574859760aec782a34ec
https://doi.org/10.1016/j.tips.2015.11.003

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Carcinogenic response and other histopathological alterations in mice exposed to cigarette smoke for varying time periods after birth

Autor: Marietta Iltcheva, Sebastiano La Maestra, Rosanna T. Micale, Gancho Ganchev, Silvio De Flora, Emilia Dimitrova, Roumen Balansky

In spite of the outstanding role of tobacco smoking in human carcinogenesis, it is difficult to reproduce its effects in experimental animals. Based on the knowledge that a variety of mechanisms account for a higher susceptibility to carcinogens earl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f6112b39d3d0f42a2ac5b88cd07b8e
http://hdl.handle.net/11567/892932

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Blood and lung microRNAs as biomarkers of pulmonary tumorigenesis in cigarette smoke-exposed mice

Autor: Mariagrazia Longobardi, Gancho Ganchev, Sebastiano La Maestra, Alessandra Pulliero, Vernon E. Steele, Alberto Izzotti, Marietta Iltcheva, Rosanna T. Micale, Silvio De Flora, Roumen Balansky, Marta Geretto, Mark Steven Miller

Publikováno v: Oncotarget

// Alberto Izzotti 1, 2 , Roumen Balansky 3 , Gancho Ganchev 3 , Marietta Iltcheva 3 , Mariagrazia Longobardi 1 , Alessandra Pulliero 1 , Marta Geretto 1 , Rosanna T. Micale 1 , Sebastiano La Maestra 1 , Mark Steven Miller 4 , Vernon E. Steele 4 , Si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1e51a6e16cc4ff6f1278950912355a
https://pubmed.ncbi.nlm.nih.gov/27713172

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Transplacental Antioxidants Inhibit Lung Tumors in Mice Exposed to Cigarette Smoke After Birth: A Novel Preventative Strategy?

Autor: Vernon E. Steele, Gancho Ganchev, R Balansky, S. De Flora, Marietta Iltcheva

Publikováno v: Current Cancer Drug Targets. 12:164-169

Birth is characterized by an intense oxidative stress resulting in nucleotide alterations and gene overexpression in mouse lung. We showed that cigarette smoke (CS) is carcinogenic when exposure starts soon after birth and applied this bioassay to ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5244e721e60fb1b7fccaa815abd6887d
https://doi.org/10.2174/156800912799095153

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Potent carcinogenicity of cigarette smoke in mice exposed early in life

Autor: Marietta Iltcheva, Silvio De Flora, Roumen Balansky, Francesco D'Agostini, Gancho Ganchev, Vernon E. Steele

Publikováno v: Carcinogenesis. 28:2236-2243

In spite of the dominant role of cigarette smoke (CS) in cancer epidemiology, all studies performed during the past 60 years have shown that this complex mixture is either negative or weakly tumorigenic in experimental animals. We implemented studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6bda3a039cd455b8a4a04ba61a83b30
https://doi.org/10.1093/carcin/bgm122

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