Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Marieta B. Heaton"'
Publikováno v:
Alcoholism: Clinical and Experimental Research. 35:1122-1133
Background: This study investigated ethanol influences on intracellular events that predispose developing neurons toward apoptosis and the capacity of the antioxidant α-tocopherol (vitamin E) and the neurotrophin brain-derived neurotrophic factor (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::761c6948bbb9008111a09d90f74a5f5d
https://doi.org/10.1111/j.1530-0277.2011.01445.x
https://doi.org/10.1111/j.1530-0277.2011.01445.x
Autor:
Marieta B. Heaton, Andy W. Neeley, Michael Paiva, Irina Madorsky, Qun Pan, Kendra I. Siler-Marsiglio, Gerry Shaw
Publikováno v:
Alcoholism: Clinical and Experimental Research. 30:1031-1038
Background: Prenatal alcohol exposure produces anatomical and behavioral abnormalities associated with fetal alcohol syndrome (FAS). Animal FAS models have demonstrated temporal windows of vulnerability in the developing cerebellum, with substantial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a23c922fce27209f8d3c1b4ce911b59
https://doi.org/10.1111/j.1530-0277.2006.000126.x
https://doi.org/10.1111/j.1530-0277.2006.000126.x
Autor:
Qun Pan, Michael Paiva, Irina Madorsky, Marieta B. Heaton, Kendra I. Siler-Marsiglio, Nila C. Khurana
Publikováno v:
Brain Research. 1052:202-211
Ethanol (EtOH) disrupts the structure and function of the developing nervous system, sometimes leading to birth defects associated with fetal alcohol syndrome (FAS). Animal FAS models indicate that cellular membrane peroxidation, intracellular oxidan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce7c8d2f6eee96b48df08026c9092b5
https://doi.org/10.1016/j.brainres.2005.06.030
https://doi.org/10.1016/j.brainres.2005.06.030
Autor:
Marieta B. Heaton, Qun Pan, Kendra I. Siler-Marsiglio, Michael Paiva, Gerry Shaw, Irina Madorsky
Publikováno v:
Journal of Neuroscience Research. 81:632-643
Exposure of the developing nervous system to ethanol (EtOH) produces neurological aberrations associated with fetal alcohol syndrome. During a well-defined period, cerebellar neurons are highly susceptible to EtOH-induced death, primarily through apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e9c4a1dfd1ea22580d62afe7314fbf
https://doi.org/10.1002/jnr.20591
https://doi.org/10.1002/jnr.20591
Autor:
Marieta B. Heaton, Kendra I. Siler-Marsiglio, Michael Paiva, Yahaira Serrano, Andy W. Neeley, Irina Madorsky
Publikováno v:
Journal of Neurobiology. 61:267-276
Pycnogenol® (PYC), a patented combination of bioflavonoids extracted from the bark of French maritime pine (Pinus maritima), inhibits apoptosis and necrosis of developing neurons exposed acutely to ethanol (EtOH). The present study shows that the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b8ef9bd7f97e34c5b50094cf6d71cfc
https://doi.org/10.1002/neu.20057
https://doi.org/10.1002/neu.20057
Publikováno v:
Journal of Neurobiology. 59:261-271
Pycnogenol (PYC), a patented combination of bioflavonoids extracted from the bark of French maritime pine (Pinus maritima), scavenges free radicals and promotes cellular health. The protective capacity of PYC against ethanol toxicity of neurons has n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92cbf90097023adb9344d4002bdb074b
https://doi.org/10.1002/neu.10311
https://doi.org/10.1002/neu.10311
Publikováno v:
Journal of Neurobiology. 60:114-126
The detrimental effects of ethanol exposure during nervous system development have been well established. The cellular mechanisms of ethanol neurotoxicity, however, have not been clearly defined. Recent studies suggest that neurotrophin signaling pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c44d86a949b16a1c12cb8514c80312c
https://doi.org/10.1002/neu.20010
https://doi.org/10.1002/neu.20010
Publikováno v:
Journal of Neurobiology. 51:160-176
The sensitivity of the developing central nervous system (CNS) to the deleterious effects of ethanol has been well documented, with exposure leading to a wide array of CNS abnormalities. Certain CNS regions are susceptible to ethanol during well-defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c82cce29eabbdb1ce4479a26fa02fae
https://doi.org/10.1002/neu.10051
https://doi.org/10.1002/neu.10051
Publikováno v:
Alcoholism, clinical and experimental research. 39(1)
Background Exposure to ethanol (EtOH) during central nervous system (CNS) development can lead to a wide array of neuroanatomical, behavioral, and cognitive abnormalities, broadly subsumed under the fetal alcohol spectrum disorder classification. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d788566b0765a06c289b7c75a81f44e6
https://pubmed.ncbi.nlm.nih.gov/25623406
https://pubmed.ncbi.nlm.nih.gov/25623406
Publikováno v:
Neuroscience Letters. 291:121-125
Neonatal rat cerebellar granule cells were used to assess the possible role of the phosphatidylinositol 3-kinase (PI3-K) signaling pathway in the neuroprotective effects of neurotrophic factors against ethanol toxicity. Culture conditions included me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6448c4d940ef26097b3714b99be7ec
https://doi.org/10.1016/s0304-3940(00)01398-7
https://doi.org/10.1016/s0304-3940(00)01398-7