Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Mariena J. A. van der Plas"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/b43ad5314c584473881e6df630addd7e
Autor:
Alma Martin, Jenny Natalie Nyman, Rikke Reinholdt, Jun Cai, Anna-Lena Schaedel, Mariena J. A. van der Plas, Martin Malmsten, Thomas Rades, Andrea Heinz
Publikováno v:
Nanomaterials, Vol 12, Iss 14, p 2437 (2022)
Nanofiber-reinforced hydrogels have recently gained attention in biomedical engineering. Such three-dimensional scaffolds show the mechanical strength and toughness of fibers while benefiting from the cooling and absorbing properties of hydrogels as
Externí odkaz:
https://doaj.org/article/95ffba9bcf3a46a6b3eca776e4a47c95
Autor:
Erik Hartman, Karl Wallblom, Mariena J. A. van der Plas, Jitka Petrlova, Jun Cai, Karim Saleh, Sven Kjellström, Artur Schmidtchen
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Wound infection is a common and serious medical condition with an unmet need for improved diagnostic tools. A peptidomic approach, aided by mass spectrometry and bioinformatics, could provide novel means of identifying new peptide biomarkers for woun
Externí odkaz:
https://doaj.org/article/011829404bbb4db69cd3c391ed863d60
Autor:
Mariena J. A. van der Plas, Ravi K. V. Bhongir, Sven Kjellström, Helena Siller, Gopinath Kasetty, Matthias Mörgelin, Artur Schmidtchen
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Neutrophil elastase cleaves thrombin generating anti-inflammatory peptides. Here the authors show that cleavage of thrombin by Pseudomonas aeruginosaelastase generates a peptide that prevents TLR dimerization and signaling, interfering with the infla
Externí odkaz:
https://doaj.org/article/1143f94b90fb4bf195cbd8188246946e
Autor:
Finja C. Hansen, Ann-Charlotte Strömdahl, Matthias Mörgelin, Artur Schmidtchen, Mariena J. A. van der Plas
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Host-defense peptides play a fundamental role in the innate immune system by modulating inflammatory responses. Previously, it was shown that the thrombin derived host-defense peptide GKY25 inhibits LPS-induced responses of monocytes and macrophages
Externí odkaz:
https://doaj.org/article/235ca3af1fcc42ac98b736f6d1cfae5b
Publikováno v:
Schmidtchen, A, Mirza, H, van der Plas, M J A, Nadeem, A & Puthia, M 2022, ' Editorial : Methods and applications in inflammation pharmacology ', Frontiers in Pharmacology, vol. 13, 1108263 . https://doi.org/10.3389/fphar.2022.1108263
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7da5e9bab62bd3632de1c9f21c1f11
https://curis.ku.dk/ws/files/333118628/Edi_Methods.pdf
https://curis.ku.dk/ws/files/333118628/Edi_Methods.pdf
Autor:
Monica Agnoletti, Mariena J. A. van der Plas, Sourav Kumar, Atin K. Mandal, Anirban Bhunia, Hanudatta S. Atreya, Humaira Ilyas, Martin Malmsten
Publikováno v:
Bioconjugate Chemistry. 32:1729-1741
Conjugation with poly(ethylene glycol) ("PEGylation") is a widely used approach for improving the therapeutic propensities of peptide and protein drugs through prolonging bloodstream circulation, reducing toxicity and immunogenicity, and improving pr
Autor:
Adam A. Strömstedt, Lina Nyström, Mariena J. A. van der Plas, Li Li, Martin Malmsten, Sara Malekkhaiat Häffner
Publikováno v:
Journal of Colloid and Interface Science. 562:71-80
Effects of size and charge of anionic nanoclays on their interactions with bacteria-mimicking lipid membranes, bacterial lipopolysaccharide (LPS), and Gram-negative bacteria were investigated using ellipsometry, dynamic light scattering, ζ-potential
Autor:
Eilish W. McBurnie, Mariena J. A. van der Plas, Peter J. Bond, Manoj Puthia, Roland G. Huber, Ganna Petruk, Artur Schmidtchen, Jitka Petrlova
Publikováno v:
The Journal of Biological Chemistry
Petrlova, J, Petruk, G, Huber, R G, McBurnie, E W, van der Plas, M J A, Bond, P J, Puthia, M & Schmidtchen, A 2020, ' Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products ', The Journal of Biological Chemistry, vol. 295, no. 11, pp. 3417-3430 . https://doi.org/10.1074/jbc.RA120.012741
Petrlova, J, Petruk, G, Huber, R G, McBurnie, E W, van der Plas, M J A, Bond, P J, Puthia, M & Schmidtchen, A 2020, ' Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products ', The Journal of Biological Chemistry, vol. 295, no. 11, pp. 3417-3430 . https://doi.org/10.1074/jbc.RA120.012741
Thrombin-derived C-terminal peptides (TCPs), including a major 11-kDa fragment (TCP96), are produced through cleavage by human neutrophil elastase and aggregate lipopolysaccharide (LPS) and the Gram-negative bacterium Escherichia coli. However, the p