Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Marielle Saclier"'
Autor:
Giuseppe Angelini, Emanuele Capra, Francesca Rossi, Giada Mura, Marielle Saclier, Valentina Taglietti, Gabriele Rovetta, Raffaele Epis, Giorgia Careccia, Chiara Bonfanti, Graziella Messina
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108696- (2024)
Summary: Muscular dystrophies (MDs) are incurable genetic myopathies characterized by progressive degeneration of skeletal muscles. Dystrophic mice lacking the transcription factor Nfix display morphological and functional improvements of the disease
Externí odkaz:
https://doaj.org/article/ff37371dfe464b6aa3fa4a6f9534b14d
Autor:
Simona Secomandi, Guido R. Gallo, Marcella Sozzoni, Alessio Iannucci, Elena Galati, Linelle Abueg, Jennifer Balacco, Manuela Caprioli, William Chow, Claudio Ciofi, Joanna Collins, Olivier Fedrigo, Luca Ferretti, Arkarachai Fungtammasan, Bettina Haase, Kerstin Howe, Woori Kwak, Gianluca Lombardo, Patrick Masterson, Graziella Messina, Anders P. Møller, Jacquelyn Mountcastle, Timothy A. Mousseau, Joan Ferrer Obiol, Anna Olivieri, Arang Rhie, Diego Rubolini, Marielle Saclier, Roscoe Stanyon, David Stucki, Françoise Thibaud-Nissen, James Torrance, Antonio Torroni, Kristina Weber, Roberto Ambrosini, Andrea Bonisoli-Alquati, Erich D. Jarvis, Luca Gianfranceschi, Giulio Formenti
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111992- (2023)
Summary: Insights into the evolution of non-model organisms are limited by the lack of reference genomes of high accuracy, completeness, and contiguity. Here, we present a chromosome-level, karyotype-validated reference genome and pangenome for the b
Externí odkaz:
https://doaj.org/article/e8b540fa7cef4bd6910b5bfb40b81e7f
Autor:
Giovanna Rigillo, Valentina Basile, Silvia Belluti, Mirko Ronzio, Elisabetta Sauta, Alessia Ciarrocchi, Lucia Latella, Marielle Saclier, Susanna Molinari, Antonio Vallarola, Graziella Messina, Roberto Mantovani, Diletta Dolfini, Carol Imbriano
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Satellite cells represent myogenic stem cells that allow the homeostasis and repair of adult skeletal muscle. Here the authors report that the transcription factor NF-Y is expressed in satellite cells and is important for their maintenance and proper
Externí odkaz:
https://doaj.org/article/c7e52b79019b4f318074386e94b4dd9f
Autor:
Giuliana Rossi, Chiara Bonfanti, Stefania Antonini, Mattia Bastoni, Stefania Monteverde, Anna Innocenzi, Marielle Saclier, Valentina Taglietti, Graziella Messina
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Strategies aimed at promoting muscle regeneration to treat muscular dystrophy have met with limited success. Here the authors show instead that delaying muscle regeneration, by ablation of the transcription factor Nfix, ameliorates muscular dystrophy
Externí odkaz:
https://doaj.org/article/4dfcc452d0b14567b01bb5bcd9666918
Autor:
Gaëtan Juban, Marielle Saclier, Houda Yacoub-Youssef, Amel Kernou, Ludovic Arnold, Camille Boisson, Sabrina Ben Larbi, Mélanie Magnan, Sylvain Cuvellier, Marine Théret, Basil J. Petrof, Isabelle Desguerre, Julien Gondin, Rémi Mounier, Bénédicte Chazaud
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2163-2176.e6 (2018)
Summary: Chronic inflammation and fibrosis characterize Duchenne muscular dystrophy (DMD). We show that pro-inflammatory macrophages are associated with fibrosis in mouse and human DMD muscle. DMD-derived Ly6Cpos macrophages exhibit a profibrotic act
Externí odkaz:
https://doaj.org/article/8e90014639484c8aa3029ac9df16f5ce
Autor:
Marielle Saclier, Michela Lapi, Chiara Bonfanti, Giuliana Rossi, Stefania Antonini, Graziella Messina
Publikováno v:
Cells, Vol 9, Iss 3, p 708 (2020)
Macrophages (MPs) are immune cells which are crucial for tissue repair. In skeletal muscle regeneration, pro-inflammatory cells first infiltrate to promote myogenic cell proliferation, then they switch into an anti-inflammatory phenotype to sustain m
Externí odkaz:
https://doaj.org/article/b9643c20eda44b10b92122597c82618b
Publikováno v:
Journal of Neuromuscular Diseases
Journal of Neuromuscular Diseases, IOS Press, 2021, 8 (4), pp.513-524. ⟨10.3233/JND-200562⟩
Journal of Neuromuscular Diseases, 2021, 8 (4), pp.513-524. ⟨10.3233/JND-200562⟩
Journal of Neuromuscular Diseases, IOS Press, 2021, 8 (4), pp.513-524. ⟨10.3233/JND-200562⟩
Journal of Neuromuscular Diseases, 2021, 8 (4), pp.513-524. ⟨10.3233/JND-200562⟩
International audience; Background: The mdx-C57/B6 mouse model does not show the clinical signs of Duchenne muscular dystrophy (DMD), although muscles exhibit hallmarks of permanent regeneration and alterations in muscle function. The DMDmdx4Cv strai
Autor:
Simona Secomandi, Guido Roberto Gallo, Marcella Sozzoni, Alessio Iannucci, Elena Galati, Linelle Abueg, Jennifer Balacco, Manuela Caprioli, William Chow, Claudio Ciofi, Joanna Collins, Olivier Fedrigo, Luca Ferretti, Arkarachai Fungtammasan, Bettina Haase, Kerstin Howe, Woori Kwak, Gianluca Lombardo, Patrick Masterson, Graziella Messina, Anders Pape Møller, Jacquelyn Mountcastle, Timothy A. Mousseau, Joan Ferrer-Obiol, Anna Olivieri, Arang Rhie, Diego Rubolini, Marielle Saclier, Roscoe Stanyon, David Stucki, Françoise Thibaud-Nissen, James Torrance, Antonio Torroni, Kristina Weber, Roberto Ambrosini, Andrea Bonisoli-Alquati, Erich D. Jarvis, Luca Gianfranceschi, Giulio Formenti
Insights into the evolution of non-model organisms are often limited by the lack of reference genomes. As part of the Vertebrate Genomes Project, we present a new reference genome and a pangenome produced with High-Fidelity long reads for the barn sw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a058f0319f61cf953d1b6e1afa3a68
https://doi.org/10.1101/2022.03.28.486082
https://doi.org/10.1101/2022.03.28.486082
Autor:
Marielle Saclier, Giuseppe Angelini, Chiara Bonfanti, Giada Mura, Giulia Temponi, Graziella Messina
Publikováno v:
The Journal of pathology. 257(3)
Muscular dystrophies are genetic diseases characterized by chronic inflammation and fibrosis. Macrophages are immune cells that sustain muscle regeneration upon acute injury but seem deleterious in the context of chronic muscle injury such as in musc
Autor:
Diletta Dolfini, Antonio Vallarola, Giovanna Rigillo, Valentina Basile, Lucia Latella, Elisabetta Sauta, Alessia Ciarrocchi, Susanna Molinari, Graziella Messina, Carol Imbriano, Roberto Mantovani, Marielle Saclier, Silvia Belluti, Mirko Ronzio
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The transcription factor NF-Y promotes cell proliferation and its activity often declines during differentiation through the regulation of NF-YA, the DNA binding subunit of the complex. In stem cell compartments, the shorter NF-YA splice variant is a