Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marielle Rath"'
Autor:
Ricardo Scheufen Tieghi, José Teófilo Moreira-Filho, Holli-Joi Martin, James Wellnitz, Miguel Canamary Otoch, Marielle Rath, Alexander Tropsha, Eugene N. Muratov, Nicole Kleinstreuer
Publikováno v:
Toxics, Vol 12, Iss 11, p 803 (2024)
Skin sensitization is a significant concern for chemical safety assessments. Traditional animal assays often fail to predict human responses accurately, and ethical constraints limit the collection of human data, necessitating a need for reliable in
Externí odkaz:
https://doaj.org/article/20b0abe052704ae18ced286a45beb8c5
Autor:
Marielle Rath, James Wellnitz, Holli-Joi Martin, Cleber Melo-Filho, Joshua Hochuli, Guilherme Martins da Silva, Jon-Michael Beasley, Travis Maxfield, Zoe Sessions, Konstantin Popov, Alexey Zakharov, Artem Cherkasov, Vinicius Alves, Eugene Muratov, Alexander Tropsha
Computational models that predict PK properties, such as those related to drug absorption, metabolism, distribution, and excretion, are critical to flagging drug candidates with poor PK profiles that emerge as hits in high-throughput screening campai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e30dfd74488af335c17be2422dc43c9f
https://doi.org/10.26434/chemrxiv-2023-rnc4l
https://doi.org/10.26434/chemrxiv-2023-rnc4l
Autor:
Vinicius Alves, Adam Yasgar, James Wellnitz, Ganesha Bantukallu, Marielle Rath, Rodolpho Braga, Stephen Capuzzi, Anton Simeonov, Eugene Muratov, Alexey Zakharov, Alexander Tropsha
Hits from high-throughput screening (HTS) of chemical libraries are often false positives due to their interference with the assay detection technology. In response to this problem, we generated the largest publicly available library of chemical liab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::173ad08e519d5b3f67df0b3ce38cb638
https://doi.org/10.26434/chemrxiv-2023-r78sj
https://doi.org/10.26434/chemrxiv-2023-r78sj