Výsledky vyhledávání - "Marielle Maurice"

The Three In-frame ATG, Clustered in the Translation Initiation Sequence of Human Factor IX Gene, Are Required for an Optimal Protein Production

Autor: Nathalie Enjolras, Marielle Maurice, Claude Negrier, O. Attali, Marie-Hélène Rodriguez, Jean-Luc Plantier

Publikováno v: Thrombosis and Haemostasis. 82:1264-1269

SummaryThree in-frame potential methionine codons have been identified in human factor IX gene and are clustered at amino acids -46, -41 and -39. In view of initiating a gene therapy approach, human factor IX production has been evaluated after modif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e49851734a7486233ea2a6f0b9211cc
https://doi.org/10.1055/s-0037-1614373

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Inverse Targeting of Retroviral Vectors: Selective Gene Transfer in a Mixed Population of Hematopoietic and Nonhematopoietic Cells

Autor: Adele K. Fielding, Marielle Maurice, Frances J. Morling, François-Löic Cosset, Stephen J. Russell

Publikováno v: Blood. 91:1802-1809

We previously reported that retroviral vectors displaying epidermal growth factor (EGF) as part of a chimeric envelope glycoprotein are sequestered upon binding to EGF receptor (EGFR)-positive target cells, leading to loss of infectivity. In the curr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07a9648b7a109b7d383a3d3ef14c644e
https://doi.org/10.1182/blood.v91.5.1802

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Inverse Targeting of Retroviral Vectors: Selective Gene Transfer in a Mixed Population of Hematopoietic and Nonhematopoietic Cells

Autor: Marielle Maurice, François-Loïc Cosset, Frances Joanne Morling, Stephen J. Russell, Adele Kay Fielding

Publikováno v: Blood. 91:1802-1809

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96f01b279c3f6bd65cc7cd2c10ea98f6
https://doi.org/10.1182/blood.v91.5.1802.1802_1802_1809

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Relationship between SU subdomains that regulate the receptor-mediated transition from the native (fusion-inhibited) to the fusion-active conformation of the murine leukemia virus glycoprotein

Autor: Dimitri Lavillette, Marielle Maurice, Bertrand Boson, Alessia Ruggieri, François-Loïc Cosset

Publikováno v: Journal of virology. 76(19)

Envelope glycoproteins (Env) of retroviruses are trimers of SU (surface) and TM (transmembrane) heterodimers and are expressed on virions in fusion-competent forms that are likely to be metastable. Activation of the viral receptor-binding domain (RBD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723dcfb93a7653fd516fbbd13612b494
https://pubmed.ncbi.nlm.nih.gov/12208946

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Microenvironmental changes during differentiation of mesenchymal stem cells towards chondrocytes

Autor: Farida Djouad, Christian Jorgensen, Pierre Charbord, Marielle Maurice, François Canovas, Pascale Louis-Plence, Bruno Delorme, Claire Bony, Florence Apparailly, Danièle Noël

Publikováno v: Arthritis Research & Therapy

Chondrogenesis is a process involving stem-cell differentiation through the coordinated effects of growth/differentiation factors and extracellular matrix (ECM) components. Recently, mesenchymal stem cells (MSCs) were found within the cartilage, whic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6095008b62000abd49435f26858f6ba0
https://doi.org/10.1186/ar2153

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Retrovirus targeting by tropism restriction to melanoma cells

Autor: Mary Collins, Marielle Maurice, François-Loïc Cosset, J. Kupsch, Francisco Martin, Stuart J. D. Neil

Publikováno v: Europe PubMed Central
Scopus-Elsevier

Targeted vectors will be necessary for many gene therapy applications. To target retroviruses to melanomas, we fused a single-chain variable fragment antibody (scFv) directed against the surface glycoprotein high-molecular-weight melanoma-associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857f22213cbac67b6fd062135731c2c9
http://europepmc.org/abstract/med/10400790

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A proline-rich motif downstream of the receptor binding domain modulates conformation and fusogenicity of murine retroviral envelopes

Autor: Stephen J. Russell, François-Loïc Cosset, Dimitri Lavillette, Marielle Maurice, Marc Sitbon, Catherine Roche

Publikováno v: Scopus-Elsevier
Europe PubMed Central
Journal of virology
Journal of virology, 1998, 72 (12), pp.9955--9965
ResearcherID
Journal of Virology
Journal of Virology, American Society for Microbiology, 1998, 72 (12), pp.9955--9965. ⟨10.1128/JVI.72.12.9955-9965.1998⟩

The entry of retroviruses into cells depends on receptor recognition by the viral envelope surface subunit SU followed by membrane fusion, which is thought to be mediated by a fusion peptide located at the amino terminus of the envelope transmembrane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7b7b36af00e04d7b09aa6e132cebe9
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031744323&partnerID=MN8TOARS

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Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide

Autor: Marielle Maurice, Patrick Salmon, François-Loïc Cosset, Stephen J. Russell, Didier Trono, Els Verhoeyen

In contrast to oncoretroviruses, lentiviruses such as human immunodeficiency virus 1 (HIV-1) are able to integrate their genetic material into the genome of nonproliferating cells that are metabolically active. Likewise, vectors derived from HIV-1 ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebec39b01e4a66820be2a7c53091fc0f
https://infoscience.epfl.ch/record/53749

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