Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Marielle Heinrich"'
Autor:
Sabine Lutz-Bonengel, Timo Sänger, Marielle Heinrich, Ulrike Schmidt, Tina Braun, Pekka Saukko
Publikováno v:
International Journal of Legal Medicine. 123:413-418
Single-nucleotide extension is a widespread method for typing Y-chromosomal single-nucleotide polymorphisms. In our study, we validated a multiplex minisequencing assay in a reduced-volume and in a low-volume approach. A four-plex assay was performed
Publikováno v:
International Journal of Legal Medicine. 123:521-525
The aim of the present study was to examine an ultrasound-accelerated fixation technique that reduces the exposure time of the tissue to formaldehyde with respect to the analysis of nucleic acids. We extracted and analysed DNA and RNA from three seri
Autor:
Stefan Pollak, Timo Sänger, Ulrike Schmidt, Sabine Lutz-Bonengel, Marielle Heinrich, Peter M. Schneider
Publikováno v:
International Journal of Legal Medicine. 122:315-321
The segregation of mitochondrial genomes and the inheritance of mitochondrial DNA are constant matters of debate. To obtain more information about this issue and to answer the question whether or not it is possible to distinguish mitochondrial DNA (m
Autor:
Sabine Lutz-Bonengel, Harald Niederstätter, Timo Sänger, Helena Müller, Marielle Heinrich, Walther Parson, Marie Follo, Joachim W. Ellwart, Ulrike Schmidt, Bernhard Bonengel
Publikováno v:
International Journal of Legal Medicine. 122:189-197
The nature of mitochondrial DNA heteroplasmy is still unclear. It could either be caused by two mitochondrial DNA (mtDNA) haplotypes coexisting within a single cell or by an admixture of homoplasmic cells, each of which contains only one type of mtDN
Publikováno v:
Forensic Science International: Genetics. 1:163-169
Relative quantification of mRNA using quantitative real-time reverse transcription (RT)-PCR is a commonly used method for analysis and comparison of gene expression levels. This method requires a normalisation of data against expression levels of a c
Publikováno v:
International Journal of Legal Medicine. 121:136-142
Recently, several authors described the observation that RNA degradation does not correlate with the postmortem interval (PMI), but rather with other parameters like environmental impact and the circumstances of death. Therefore, the question arose i
Publikováno v:
International Journal of Legal Medicine. 121:68-73
Low volume (LV) amplification (1 microL) of nuclear DNA (nucDNA) on a chemically structured chip is an appropriate and highly sensitive method to simultaneously amplify amelogenin and 15 forensically relevant short tandem repeats (STR). In this study
Autor:
Juan J. Sanchez, Bertrand Ludes, Bernardette Hoste, Conceiçao Vide, B. Mevåg, Berit Myhre Dupuy, Nathalie Siebert, Harald Niederstätter, Maria Brion, Niels Morling, Walther Parson, Carsten Hohoff, C.R. Thacker, Klaus Bender, Marielle Heinrich, Angel Carracedo
Publikováno v:
Forensic Science International. 153:103-108
A collaborative study was carried out by the European DNA Profiling Group (EDNAP) in order to evaluate the performance of Y-chromosome binary polymorphism analysis in different European laboratories. Four blood samples were sent to the laboratories,
Autor:
Sahar Elias, Carsten Hohoff, Micaela Poetsch, Sławomir Lewicki, Katja Anslinger, Tadeusz Dobosz, Manfred Kayser, Oscar Lao, R. Wegener, Beate Stradmann-Bellinghausen, Rüdiger Lessig, Agnieszka Maciejewska, Grazyna Bargel, Piotr Kuzniar, Lotte Henke, Arleta Lebioda, Jeanett Edelmann, Marielle Heinrich, Dorota Monies, Christa Augustin, Anna Jonkisz, Magdalena Zoledziewska, Rafał Płoski, Jürgen Henke, Ulrike Schmidt, Marcin Wozniak, Dagmar Schmid, Reinhard Szibor, Anett Illing, Lutz Roewer, Peter M. Schneider, Ryszard Pawłowski
Publikováno v:
Human Genetics, 117(5), 428-443. Springer-Verlag
To test for human population substructure and to investigate human population history we have analysed Y-chromosome diversity using seven microsatellites (Y-STRs) and ten binary markers (Y-SNPs) in samples from eight regionally distributed population
Autor:
Marielle Heinrich, Benedikt Vennemann, T. Fracasso, Antje Koppelkamm, Ulrike Schmidt, Sabine Lutz-Bonengel
Publikováno v:
International journal of legal medicine. 124(5)
Gene expression analyses based on messenger RNA (mRNA) profiling require accurate data normalisation. When using endogenous reference genes, these have to be validated carefully. Therefore, we examined the transcript stability of 10 potential referen