Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marielle Christ"'
Autor:
Guillaume Ravel, Fabienne Condevaux, Jacques Descotes, Marie-France Perron-Lepage, Marielle Christ
Publikováno v:
Journal of Immunotoxicology. 1:141-148
Pre-existing or contributing risk factors, including genetic predisposition and environmental influences, are largely thought to play a crucial (though ill-elucidated) role in the development of autoimmunity. Trichloroethylene (TCE) is a widely used
Publikováno v:
Toxicology. 200:247-254
The popliteal lymph node assay (PLNA) is being considered as a tool to predict the potential of drugs for inducing systemic autoimmune and hypersensitivity reactions. Despite the use of different technical approaches and the evaluation of over 130 co
Publikováno v:
Toxicology. 196:211-216
Although the wide clinical experience shows that vaccines are generally safe, concern has been expressed for a causal link between vaccines and autoimmune diseases. Even though the mechanisms of autoimmunity are ill-elucidated, the role of pre-existi
Publikováno v:
Toxicology Letters. 146:93-100
The induction or exacerbation of autoimmune diseases is a potential adverse effect of immunostimulating drugs. Vaccines have been suspected of such actions. Epidemiological studies, however, have so far failed to demonstrate any causal relationship b
Autor:
Marielle Christ, Philippe Martel, François Tron, Maryvonne Daveau, Danièle Gilbert, Pascal Joly, G Raux
Publikováno v:
Journal of Autoimmunity. 14:79-82
Association of kappa light chain immunoglobulin allotypes with bullous pemphigoid was examined in 101 Caucasian patients. Km alleles were determined by polymerase chain reaction amplification followed by restriction enzyme digestion. The frequency of
Autor:
Karine Aupeix, Jean-Marie Freyssinet, Marielle Christ, D. Weltin, José E. Mejía, Jean Marchal, Pierre Bischoff
Publikováno v:
Immunobiology. 194:415-428
Oxysterols constitute a large family of natural compounds, endowed with various biological activities including cholesterol regulation, immunosuppression and antitumoral potency. In the present study, we examine and compare the cytotoxic effects of t
Autor:
Hongsheng Tian, Marielle Christ, Leo T. Furcht, Sharon M. Wahl, Keith L. Hines, Ashok B. Kulkarni, Stefan Karlsson, James B. McCarthy, Nancy McCartney-Francis, Jerrold M. Ward
Publikováno v:
Proceedings of the National Academy of Sciences. 91:5187-5191
Pronounced mononuclear leukocyte (MNL) infiltration occurs in multiple organs of mice homozygous for a transforming growth factor beta 1 (TGF-beta 1) loss-of-function gene mutation [TGF-beta 1 (-/-)], followed by cachexia and eventually death. Consis
Publikováno v:
ImmunoMethods. 3:13-22
Cytokine interactions are central to the development of immune and inflammatory responses. While in vitro assays provide evidence about specific activities of individual cytokines, they are less informative concerning cytokine interactions that const
Autor:
Marielle Christ
Publikováno v:
Toxicology. 174(1)
As any new drug in development, gene transfer products have to be tested for their potential toxicity in preclinical studies. Strategies for preclinical safety evaluation of gene transfer compounds are similar to those undertaken for biotechnology-de